NaturalProductMech

sirodesmin PL

naturalproductmech:mibig-6dc3684890 MINTED SEEDED

Structure

Standard InChIKeyKTAIGLOGMSQPCG-OQIMMBKLSA-N
SMILESC[C@@H]1C(C(=O)[C@]2(O1)C[C@@H]3[C@]([C@@H]2OC(=O)C)(C[C@]45N3C(=O)[C@](N(C4=O)C)(SS5)CO)O)(C)C
Stereochemistryfully defined
Cross-referencespubchem:15608374

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Leptosphaeria maculans
NCBITaxon:5022
SOURCE_ASSERTION mibig:BGC0001044 DOI:10.1128/aem.55.6.1555-1559.1989

Occurrences 7

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1016/0021-9673(90)85168-U
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1016/0031-9422(90)80017-B
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1016/0040-4039(88)85192-X
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1016/J.BMC.2008.07.060
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1021/JA00187A068
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1039/P19800001739
Leptosphaeria maculans
NCBITaxon:5022
LOTUS DOI:10.1111/J.1365-2958.2004.04215.X

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001044 Leptosphaeria maculans
NCBITaxon:5022
CLUSTER_UNSTATED genbank:AY553235.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001044MIBIG4

This page is generated from data/natural_products/unclassified/sirodesmin-pl.yaml, which is generated from the committed inventories. Neither is edited by hand.