NaturalProductMech

spiruchostatin A

naturalproductmech:mibig-e45a0be092 MINTED SEEDED

Structure

Standard InChIKeyXFLBOEMFLGLWFF-RCYPOCGFSA-N
SMILES[H][C@]12CSSCC\C=C\C(CC(=O)N[C@H](C)C(=O)N1)OC(=O)CC(O)C(NC2=O)C(C)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA07276, pubchem:60209141

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pseudomonas sp. Q71576
NCBITaxon:1231908
SOURCE_ASSERTION mibig:BGC0001045 PMID:24973954

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pseudomonas
NCBITaxon:286
LOTUS DOI:10.1016/S0040-4039(00)01874-8

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001045 Pseudomonas sp. Q71576
NCBITaxon:1231908
CLUSTER_UNSTATED genbank:JQ045344.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001045MIBIG5

This page is generated from data/natural_products/unclassified/spiruchostatin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.