subglutinol A

naturalproductmech:mibig-eb42b809a5 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKey	SXNPXUJAUIINIU-JTLRLOPKSA-N
SMILES	CC1=C(OC(=O)C(=C1O)C[C@@H]2C(=C)CC[C@@H]3[C@@]2(CC[C@H]4[C@]3(C[C@H](O4)C=C(C)C)C)C)C
Stereochemistry	fully defined
Cross-references	npatlas:NPA003785

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, pks, nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Metarhizium robertsii ARSEF 23 NCBITaxon:655844	SOURCE_ASSERTION	mibig:BGC0002427	PMID:32286350
Penicillium shearii NCBITaxon:904690	SOURCE_ASSERTION	mibig:BGC0002614	PMID:32286350

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Fusarium subglutinans NCBITaxon:42677	LOTUS	DOI:10.1021/JO00127A001
Fusarium fujikuroi NCBITaxon:5127	LOTUS	DOI:10.1021/JO00127A001

Biosynthetic gene clusters 2

Accession	Host	Locus evidence	Genome
mibig:BGC0002427	Metarhizium robertsii ARSEF 23 NCBITaxon:655844	CLUSTER_DEMONSTRATED	genbank:ADNJ02000014.1
mibig:BGC0002614	Penicillium shearii NCBITaxon:904690	CLUSTER_DEMONSTRATED	genbank:LC600199.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Explore across X-Mech

AntibioticMech (subglutinol A) ↗ MediaIngredientMech (naturalproductmech:mibig-eb42b809a5) ↗ TaxonMech: Metarhizium robertsii ARSEF 23 (NCBITaxon:655844) ↗ TaxonMech: Penicillium shearii (NCBITaxon:904690) ↗ PathwayMech (mibig:BGC0002427) ↗ PathwayMech (mibig:BGC0002614) ↗

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002427, BGC0002614. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source concept	Source	Version
BGC0002427	MIBIG	2
BGC0002614	MIBIG	2

This page is generated from data/natural_products/unclassified/subglutinol-a.yaml, which is generated from the committed inventories. Neither is edited by hand.