NaturalProductMech

SW-163E

naturalproductmech:mibig-89c381d425 MINTED SEEDED

Structure

Standard InChIKeyPVGUHCMGVWCBAB-UHFFFAOYSA-N
SMILESCCSC1SCC2N(C)C(=O)C(C)NC(=O)C(COC(=O)C3(CC3C)N(C)C(=O)C1N(C)C(=O)C(C)NC(=O)C(COC(=O)C1(CC1C)N(C)C2=O)NC(=O)C1=C(O)C=C2C=CC=CC2=N1)NC(=O)C1=NC2=CC=CC=C2C=C1O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA016133, pubchem:6857739

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. SNA15896
NCBITaxon:497689
SOURCE_ASSERTION mibig:BGC0000434 PMID:19514719

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.7164/ANTIBIOTICS.54.615
Escherichia coli
NCBITaxon:562
LOTUS DOI:10.1021/JA902261A

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000434 Streptomyces sp. SNA15896
NCBITaxon:497689
CLUSTER_UNSTATED genbank:AB375771.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000434MIBIG5

This page is generated from data/natural_products/unclassified/sw-163e.yaml, which is generated from the committed inventories. Neither is edited by hand.