teixobactin
naturalproductmech:mibig-04593f87e6 MINTED SEEDED
Structure
| Standard InChIKey | LMBFAGIMSUYTBN-IIRRRCHSSA-N |
|---|---|
| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H]1[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](C[C@H]2CN=C(N)N2)NC(=O)[C@H](C)NC1=O)[C@@H](C)CC |
| Stereochemistry | fully defined |
| Cross-references | pubchem:86341926, npatlas:NPA013751 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Eleftheria terrae NCBITaxon:1597781 |
SOURCE_ASSERTION | mibig:BGC0001207 | DOI:10.1038/nature14098 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001207 | Eleftheria terrae NCBITaxon:1597781 |
CLUSTER_UNSTATED | genbank:KP006601.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| Inhibition Assay from US Patent US9402878: "Depsipeptide and uses thereof" | IC50 100 uM | pubchem.aid:1803122 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001207 | MIBIG | 5 |
This page is generated from data/natural_products/unclassified/teixobactin.yaml, which is generated from the committed inventories. Neither is edited by hand.