thiocoraline
naturalproductmech:mibig-e8046d131e MINTED SEEDED
Structure
| Standard InChIKey | UPGGKUQISSWRJJ-UHFFFAOYSA-N |
|---|---|
| SMILES | CSCC1N(C)C(=O)C2CSSCC(N(C)C(=O)CNC(=O)C(CSC1=O)NC(=O)C1=NC3=CC=CC=C3C=C1O)C(=O)N(C)C(CSC)C(=O)SCC(NC(=O)C1=C(O)C=C3C=CC=CC3=N1)C(=O)NCC(=O)N2C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA019774 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora sp. ML1 NCBITaxon:349725 |
BGC_CHARACTERIZED | mibig:BGC0000445 | PMID:16408310 |
Occurrences 5
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Micromonospora NCBITaxon:1873 |
LOTUS | DOI:10.7164/ANTIBIOTICS.50.734 |
| Streptomyces albus NCBITaxon:1888 |
LOTUS | DOI:10.1007/S00253-013-5440-6 |
| Streptomyces albus NCBITaxon:1888 |
LOTUS | DOI:10.1186/1471-2164-15-97 |
| Micromonospora marina NCBITaxon:307120 |
LOTUS | DOI:10.1038/SJ.BJC.6690451 |
| Micromonospora marina NCBITaxon:307120 |
LOTUS | DOI:10.7164/ANTIBIOTICS.50.734 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000445 | Micromonospora sp. ML1 NCBITaxon:349725 |
CLUSTER_DEMONSTRATED | genbank:AM113472.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000445 | MIBIG | 5 |
This page is generated from data/natural_products/unclassified/thiocoraline.yaml, which is generated from the committed inventories. Neither is edited by hand.