NaturalProductMech

tolaasin F

naturalproductmech:mibig-a27f568cc1 MINTED SEEDED

Structure

Standard InChIKeyGNSYIOGOBDUEMK-HGHFYUPGSA-N
SMILESO=C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N1)=O)CCO)=O)=O)[C@@H](C)OC([C@H](CCCCN)NC([C@H]1CCN)=O)=O)/C(NC([C@@H](C(C)C)NC([C@H](CC(C)C)NC([C@@H](CCC(N)=O)NC([C@@H](C(C)C)NC([C@@H](C(C)C)NC([C@@H](CC(C)C)NC([C@@H](CO)NC([C@@H](C(C)C)NC([C@@H](CC(C)C)NC([C@@H](CO)NC([C@H]2N(C(/C(NC(CC(CCCCC)O)=O)=C/C)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=C/C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pseudomonas costantinii
NCBITaxon:168469
BGC_CHARACTERIZED mibig:BGC0000447 PMID:24222604

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pseudomonas tolaasii
NCBITaxon:29442
LOTUS DOI:10.1002/CBIC.201300553

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000447 Pseudomonas costantinii
NCBITaxon:168469
CLUSTER_DEMONSTRATED genbank:HE967327.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000447MIBIG5

This page is generated from data/natural_products/unclassified/tolaasin-f.yaml, which is generated from the committed inventories. Neither is edited by hand.