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vicenistatin

naturalproductmech:mibig-02d70de917 MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyFINGADBUNZWVLV-VVAVUVFHSA-N
SMILESC[C@@H]1[C@H]([C@H](C[C@@H](O1)OC2C/C=C(/C/C(=C/C=C/CCC(CNC(=O)/C=C/C=C/C2C)C)/C)\C)O)NC
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA017222, pubchem:6438888

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, nrps, other, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces parvus
NCBITaxon:66428
BGC_CHARACTERIZED mibig:BGC0002634 PMID:35042332
Streptomyces halstedii
NCBITaxon:1944
SOURCE_ASSERTION mibig:BGC0000167 PMID:15112997

Occurrences 0

None cited.

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002634 Streptomyces parvus
NCBITaxon:66428
CLUSTER_DEMONSTRATED genbank:OL310481.1
mibig:BGC0000167 Streptomyces halstedii
NCBITaxon:1944
CLUSTER_UNSTATED genbank:AB086653.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 2 producers (1 causal) 0 cited occurrences BIOSYNTHETIC LOCUS 2 gene clusters 0 curated pathway steps NATURAL PRODUCT vicenistatin naturalproductmech:mibig-02d70de917 Unclassified TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

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Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000167, BGC0002634. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002634MIBIG2
BGC0000167MIBIG5

This page is generated from data/natural_products/unclassified/vicenistatin.yaml, which is generated from the committed inventories. Neither is edited by hand.