viridicatumtoxin
CHEBI:85616 EXACT SEEDED antimicrobial unspecified
A tetracycline-like polyketide antibiotic that is produced by several species of Penicillium and Aspergillus.
Structure
| Standard InChIKey | SUWQGLGDFGHZNH-WBWZXODPSA-N |
|---|---|
| SMILES | COC1=C2C3=C(C(O)=C1)C(O)=C1C(=O)[C@]4(O)C(=O)C(C(N)=O)=C(O)C[C@]4(O)[C@@H](O)C1=C3C[C@]21C(C)=CCCC1(C)C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA03651, pubchem:54679209 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Penicillium aethiopicum NCBITaxon:36650 |
BGC_CHARACTERIZED | mibig:BGC0000168 | DOI:10.1016/j.chembiol.2010.03.015 |
Occurrences 9
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Penicillium brasilianum NCBITaxon:104259 |
LOTUS | DOI:10.1038/JA.2012.83 |
| Penicillium brasilianum NCBITaxon:104259 |
CHEBI | PMID:23168407 |
| Aspergillus ustus NCBITaxon:40382 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0116089 |
| Aspergillus ustus NCBITaxon:40382 |
CHEBI | PMID:25706180 |
| Aspergillus unilateralis NCBITaxon:41057 |
LOTUS | DOI:10.1002/CHIN.200523199 |
| Eupenicillium NCBITaxon:5073 |
LOTUS | DOI:10.1021/NP500111W |
| Penicillium aethiopicum NCBITaxon:36650 |
LOTUS | DOI:10.1016/J.CHEMBIOL.2010.03.015 |
| Penicillium aethiopicum NCBITaxon:36650 |
LOTUS | DOI:10.1021/JA3028636 |
| Penicillium aethiopicum NCBITaxon:36650 |
CHEBI | PMID:22590971 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000168 | Penicillium aethiopicum NCBITaxon:36650 |
CLUSTER_DEMONSTRATED | genbank:GU574477.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| HERG Channel Activity | ACTIVE | pubchem.aid:376 |
Elsewhere in the fleet
- AntibioticMech — CHEBI:85616 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000168 | MIBIG | 5 |
| CHEBI:85616 | CHEBI | 3-star |
This page is generated from data/natural_products/unclassified/viridicatumtoxin.yaml, which is generated from the committed inventories. Neither is edited by hand.