waikikiamide B
naturalproductmech:mibig-7d6d6d4f4a MINTED SEEDED
Structure
| Standard InChIKey | DKMOFXIZKXGGIM-DKGQAOFKSA-N |
|---|---|
| SMILES | COC1=CC2=CC3=C(C(=O)O[C@H](C)C3)C(O)=C2C2=C1[C@H]1[C@@]3(O2)C(=NC2=C3C=CC3=C2C=CC(C)(C)O3)C(C)(C)[C@@H]2C[C@]34CCCN3C(=O)[C@@]21NC4=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA032307 |
Filing pathway
Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus sp. FM242 NCBITaxon:2741095 |
SOURCE_ASSERTION | mibig:BGC0002253 | PMID:32433885 |
| Aspergillus sp. FM242 NCBITaxon:2741095 |
SOURCE_ASSERTION | mibig:BGC0002254 | PMID:32433885 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aspergillus NCBITaxon:5052 |
LOTUS | DOI:10.1021/ACS.ORGLETT.0C01411 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002253 | Aspergillus sp. FM242 NCBITaxon:2741095 |
CLUSTER_UNSTATED | genbank:MT457560.1 |
| mibig:BGC0002254 | Aspergillus sp. FM242 NCBITaxon:2741095 |
CLUSTER_UNSTATED | genbank:MT457561.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0002253, BGC0002254. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002253 | MIBIG | 3 |
| BGC0002254 | MIBIG | 3 |
This page is generated from data/natural_products/unclassified/waikikiamide-b.yaml, which is generated from the committed inventories. Neither is edited by hand.