NaturalProductMech

waikikiamide C

naturalproductmech:mibig-689f97d555 MINTED SEEDED

Structure

Standard InChIKeyGKOOPMJBANLQKC-DXXYEOPISA-N
SMILESCO[C@H]1C2=C(N(O)C3=C2C=CC2=C3[C@@H](OC)[C@H](ON3C(=O)[C@@]4(C[C@@]56NC(=O)[C@]7(CCCN7C5=O)C[C@H]6C4(C)C)C4=C3C3=C(C=C4)OC(C)(C)C=C3)C(C)(C)O2)C(C)(C)[C@@H]2C[C@]34CCCN3C(=O)[C@]12NC4=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA032308

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Aspergillus sp. FM242
NCBITaxon:2741095
SOURCE_ASSERTION mibig:BGC0002253 PMID:32433885
Aspergillus sp. FM242
NCBITaxon:2741095
SOURCE_ASSERTION mibig:BGC0002254 PMID:32433885

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus
NCBITaxon:5052
LOTUS DOI:10.1021/ACS.ORGLETT.0C01411

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002253 Aspergillus sp. FM242
NCBITaxon:2741095
CLUSTER_UNSTATED genbank:MT457560.1
mibig:BGC0002254 Aspergillus sp. FM242
NCBITaxon:2741095
CLUSTER_UNSTATED genbank:MT457561.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002253, BGC0002254. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002253MIBIG3
BGC0002254MIBIG3

This page is generated from data/natural_products/unclassified/waikikiamide-c.yaml, which is generated from the committed inventories. Neither is edited by hand.