NaturalProductMech

WS9326A

naturalproductmech:mibig-f329415ee7 MINTED SEEDED

Structure

Standard InChIKeyBVVWVQZZLUNSNV-QMXPZCTJSA-N
SMILESCCC/C=C\C1=CC=CC=C1/C=C/C(=O)N[C@H]2[C@H](OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)/C(=C\C3=CC=C(C=C3)O)/N(C2=O)C)CC(C)C)CC4=CC=CC=C4)[C@H](C)O)CC(=O)N)CO)C
Stereochemistryfully defined
Cross-referenceschembl:CHEMBL3740058, pubchem:6918144, CHEBI:210268, npatlas:NPA018526, pubchem:6441210

Filing pathway

Unclassified — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces calvus
NCBITaxon:67282
SOURCE_ASSERTION mibig:BGC0001297 PMID:1381344
Streptomyces sp. SNM55
NCBITaxon:1571707
SOURCE_ASSERTION mibig:BGC0002377 PMID:33963654

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Arthrobacter
NCBITaxon:1663
LOTUS DOI:10.1021/ACS.JNATPROD.5B00540
Streptomyces asterosporus
NCBITaxon:67282
LOTUS DOI:10.1002/CBIC.201700428
Streptomyces asterosporus
NCBITaxon:67282
LOTUS DOI:10.1021/OL302298K

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0001297 Streptomyces calvus
NCBITaxon:67282
CLUSTER_UNSTATED genbank:KT362217.1
mibig:BGC0002377 Streptomyces sp. SNM55
NCBITaxon:1571707
CLUSTER_UNSTATED genbank:MH243323.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001297, BGC0002377. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001297MIBIG4
BGC0002377MIBIG2

This page is generated from data/natural_products/unclassified/ws9326a.yaml, which is generated from the committed inventories. Neither is edited by hand.