Ubiquinol-6 biosynthesis from 4-hydroxybenzoate

WikiPathways:WP287

Ubiquinol-6 biosynthesis from 4-hydroxybenzoate prenylates 4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate, then modifies the aromatic ring through hydroxylation, methylation, decarboxylation, and reduction steps to form ubiquinol-6 in Saccharomyces cerevisiae.

Pathway type
cofactor biosynthesis
Organism scope

Read the source YAML

Pathway network

37 nodes · 52 asserted directed edges

Arrows show recorded subject → object relationships, not necessarily metabolic flow. Select a node for details or an arrow for evidence. Scroll, zoom or find a node to explore.

Pathway network: Ubiquinol-6 biosynthesis from 4-hydroxybenzoate 37 nodes · 52 asserted directed edges. Every arrow links to its evidence table row; nodes link to their component details. Isolated declared components are retained. CHEBI:61472 — consumes → WikiPathways:WP287/id1105b8d9; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id1105b8d9 — produces → CHEBI:61473; Evidence: WikiPathways:WP287produces CHEBI:30763 — consumes → WikiPathways:WP287/id46b5e257; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id46b5e257 — produces → CHEBI:84492; Evidence: WikiPathways:WP287produces CHEBI:84492 — consumes → WikiPathways:WP287/id4c332e28; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id4c332e28 — produces → CHEBI:58373; Evidence: WikiPathways:WP287produces CHEBI:57916 — consumes → WikiPathways:WP287/id55520bdd; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id55520bdd — produces → CHEBI:1109; Evidence: WikiPathways:WP287produces CHEBI:58373 — consumes → WikiPathways:WP287/id646fb25b; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id646fb25b — produces → CHEBI:57916; Evidence: WikiPathways:WP287produces CHEBI:1109 — consumes → WikiPathways:WP287/id74367dd4; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id74367dd4 — produces → CHEBI:61472; Evidence: WikiPathways:WP287produces CHEBI:64253 — consumes → WikiPathways:WP287/id86d34e80; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id86d34e80 — produces → CHEBI:52970; Evidence: WikiPathways:WP287produces CHEBI:61473 — consumes → WikiPathways:WP287/idac01794e; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/idac01794e — produces → CHEBI:64253; Evidence: WikiPathways:WP287produces CHEBI:15378 — consumes → WikiPathways:WP287/id55520bdd; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id74367dd4 — produces → CHEBI:58349; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id74367dd4 — produces → CHEBI:15377; Evidence: WikiPathways:WP287produces SGD:S000003487 — catalyzes → WikiPathways:WP287/id74367dd4; Evidence: WikiPathways:WP287catalyzes CHEBI:59789 — consumes → WikiPathways:WP287/id646fb25b; Evidence: WikiPathways:WP287consumes CHEBI:59789 — consumes → WikiPathways:WP287/id86d34e80; Evidence: WikiPathways:WP287consumes SGD:S000003487 — catalyzes → WikiPathways:WP287/id4c332e28; Evidence: WikiPathways:WP287catalyzes CHEBI:17499 — consumes → WikiPathways:WP287/idac01794e; Evidence: WikiPathways:WP287consumes CHEBI:15379 — consumes → WikiPathways:WP287/idac01794e; Evidence: WikiPathways:WP287consumes CHEBI:58179 — consumes → WikiPathways:WP287/id46b5e257; Evidence: WikiPathways:WP287consumes CHEBI:15379 — consumes → WikiPathways:WP287/id4c332e28; Evidence: WikiPathways:WP287consumes CHEBI:15378 — consumes → WikiPathways:WP287/id4c332e28; Evidence: WikiPathways:WP287consumes CHEBI:15378 — consumes → WikiPathways:WP287/id74367dd4; Evidence: WikiPathways:WP287consumes CHEBI:57783 — consumes → WikiPathways:WP287/id74367dd4; Evidence: WikiPathways:WP287consumes CHEBI:15379 — consumes → WikiPathways:WP287/id74367dd4; Evidence: WikiPathways:WP287consumes SGD:S000005456 — catalyzes → WikiPathways:WP287/id86d34e80; Evidence: WikiPathways:WP287catalyzes WikiPathways:WP287/id4c332e28 — produces → CHEBI:15377; Evidence: WikiPathways:WP287produces SGD:S000005324 — catalyzes → WikiPathways:WP287/id46b5e257; Evidence: WikiPathways:WP287catalyzes WikiPathways:WP287/id86d34e80 — produces → CHEBI:57856; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id86d34e80 — produces → CHEBI:15378; Evidence: WikiPathways:WP287produces SGD:S000005456 — catalyzes → WikiPathways:WP287/id646fb25b; Evidence: WikiPathways:WP287catalyzes SGD:S000005651 — catalyzes → WikiPathways:WP287/idac01794e; Evidence: WikiPathways:WP287catalyzes WikiPathways:WP287/id1105b8d9 — produces → CHEBI:57856; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id1105b8d9 — produces → CHEBI:15378; Evidence: WikiPathways:WP287produces CHEBI:59789 — consumes → WikiPathways:WP287/id1105b8d9; Evidence: WikiPathways:WP287consumes WikiPathways:WP287/id55520bdd — produces → CHEBI:16526; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id46b5e257 — produces → CHEBI:33019; Evidence: WikiPathways:WP287produces SGD:S000004578 — catalyzes → WikiPathways:WP287/id1105b8d9; Evidence: WikiPathways:WP287catalyzes WikiPathways:WP287/idac01794e — produces → CHEBI:15339; Evidence: WikiPathways:WP287produces WikiPathways:WP287/idac01794e — produces → CHEBI:15377; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id646fb25b — produces → CHEBI:57856; Evidence: WikiPathways:WP287produces WikiPathways:WP287/id646fb25b — produces → CHEBI:15378; Evidence: WikiPathways:WP287produces SGD:S000003487 — has_cofactor → CHEBI:57692; UniProtKB reviewed (Swiss-Prot) annotation. Reviewed source qualification: The caution limits deamination in other taxa and does not negate the yeast FAD cofactor annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03193); ECO:0000269 (PubMed:26808124); Evidence: UniProtKB:P53318, UniProtKB:P53318has cofactor SGD:S000005456 — has_cofactor → CHEBI:18420; UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03190); Evidence: UniProtKB:P27680, UniProtKB:P27680has cofactor SGD:S000005324 — has_cofactor → CHEBI:18420; UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03189); ECO:0000269 (PubMed:1740455); Evidence: UniProtKB:P32378, UniProtKB:P32378has cofactor SGD:S000005651 — has_cofactor → CHEBI:24875; UniProtKB reviewed (Swiss-Prot) annotation. Reviewed source qualification: Carbon catabolite repression was an indirect phenotype, not the enzyme function; retain the inferred iron cofactor annotation without adding regulatory causality. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03194) Binds 2 iron ions per subunit. UniProt note evidence: ECO:0000255 (HAMAP-Rule:MF_03194); Evidence: UniProtKB:P41735, UniProtKB:P41735has cofactor COQ6; SGD:S000003487; Declared type: protein protein COQ6 COQ3; SGD:S000005456; Declared type: protein protein COQ3 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate; CHEBI:58373; Declared type: small_molecule small molecule 3,4-dihydroxy-5-all-trans- hexaprenylbenzoate ubiquinol-6; CHEBI:52970; Declared type: small_molecule small molecule ubiquinol-6 COQ2; SGD:S000005324; Declared type: protein protein COQ2 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate; CHEBI:57916; Declared type: small_molecule small molecule 3-methoxy-4-hydroxy-5-all- trans-hexaprenylbenzoate diphosphate(3-); CHEBI:33019; Declared type: small_molecule small molecule diphosphate(3-) CAT5; SGD:S000005651; Declared type: protein protein CAT5 hydrogen donor; CHEBI:17499; Declared type: small_molecule small molecule hydrogen donor COQ5; SGD:S000004578; Declared type: protein protein COQ5 S-adenosyl-L-methionine zwitterion; CHEBI:59789; Declared type: small_molecule small molecule S-adenosyl-L-methionine zwitterion 4-hydroxybenzoate; CHEBI:30763; Declared type: small_molecule small molecule 4-hydroxybenzoate 3-hexaprenyl-4-hydroxybenzoate; CHEBI:84492; Declared type: small_molecule small molecule 3-hexaprenyl-4- hydroxybenzoate all-trans-hexaprenyl diphosphate(3-); CHEBI:58179; Declared type: small_molecule small molecule all-trans-hexaprenyl diphosphate(3-) dioxygen; CHEBI:15379; Declared type: small_molecule small molecule dioxygen hydron; CHEBI:15378; Declared type: small_molecule small molecule hydron water; CHEBI:15377; Declared type: small_molecule small molecule water NADP(3-); CHEBI:58349; Declared type: small_molecule small molecule NADP(3-) S-adenosyl-L-homocysteine zwitterion; CHEBI:57856; Declared type: small_molecule small molecule S-adenosyl-L-homocysteine zwitterion 2-hexaprenyl-6-methoxyphenol; CHEBI:1109; Declared type: small_molecule small molecule 2-hexaprenyl-6-methoxyphenol carbon dioxide; CHEBI:16526; Declared type: small_molecule small molecule carbon dioxide 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol; CHEBI:61472; Declared type: small_molecule small molecule 2-methoxy-6-all-trans- hexaprenyl-1,4-benzoquinol NADPH(4-); CHEBI:57783; Declared type: small_molecule small molecule NADPH(4-) 3-demethylubiquinol-6; CHEBI:64253; Declared type: small_molecule small molecule 3-demethylubiquinol-6 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol; CHEBI:61473; Declared type: small_molecule small molecule 6-methoxy-3-methyl-2-all- trans- hexaprenyl-1,4-benzoquinol acceptor; CHEBI:15339; Declared type: small_molecule small molecule acceptor FAD(3-); CHEBI:57692; Declared type: cofactor cofactor FAD(3-) magnesium(2+); CHEBI:18420; Declared type: cofactor cofactor magnesium(2+) iron cation; CHEBI:24875; Declared type: cofactor cofactor iron cation 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction; WikiPathways:WP287/id1105b8d9; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 2-methoxy-6-all-trans- hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all- trans- hexaprenyl-1,4-benzoquinol GPML interaction 4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction; WikiPathways:WP287/id46b5e257; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 4-hydroxybenzoate to 3- hexaprenyl-4-hydroxybenzoate GPML interaction 3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction; WikiPathways:WP287/id4c332e28; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 3-hexaprenyl-4- hydroxybenzoate to 3,4-dihydroxy-5-all-trans- hexaprenylbenzoate GPML interaction 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction; WikiPathways:WP287/id55520bdd; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 3-methoxy-4-hydroxy-5-all- trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction; WikiPathways:WP287/id646fb25b; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 3,4-dihydroxy-5-all-trans- hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all- trans-hexaprenylbenzoate GPML interaction 2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction; WikiPathways:WP287/id74367dd4; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans- hexaprenyl-1,4-benzoquinol GPML interaction 3-demethylubiquinol-6 to ubiquinol-6 GPML interaction; WikiPathways:WP287/id86d34e80; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 3-demethylubiquinol-6 to ubiquinol-6 GPML interaction 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction; WikiPathways:WP287/idac01794e; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 6-methoxy-3-methyl-2-all- trans- hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction

Components and activities

Declared biological components and source reaction directions
NodeKind or roleSource direction
Saccharomyces cerevisiae
NCBITaxon:4932		taxon
COQ6
SGD:S000003487		protein
COQ3
SGD:S000005456		protein
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:58373		small molecule
ubiquinol-6
CHEBI:52970		small molecule
COQ2
SGD:S000005324		protein
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:57916		small molecule
diphosphate(3-)
CHEBI:33019		small molecule
CAT5
SGD:S000005651		protein
hydrogen donor
CHEBI:17499		small molecule
COQ5
SGD:S000004578		protein
S-adenosyl-L-methionine zwitterion
CHEBI:59789		small molecule
4-hydroxybenzoate
CHEBI:30763		small molecule
3-hexaprenyl-4-hydroxybenzoate
CHEBI:84492		small molecule
all-trans-hexaprenyl diphosphate(3-)
CHEBI:58179		small molecule
dioxygen
CHEBI:15379		small molecule
hydron
CHEBI:15378		small molecule
water
CHEBI:15377		small molecule
NADP(3-)
CHEBI:58349		small molecule
S-adenosyl-L-homocysteine zwitterion
CHEBI:57856		small molecule
2-hexaprenyl-6-methoxyphenol
CHEBI:1109		small molecule
carbon dioxide
CHEBI:16526		small molecule
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61472		small molecule
NADPH(4-)
CHEBI:57783		small molecule
3-demethylubiquinol-6
CHEBI:64253		small molecule
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61473		small molecule
acceptor
CHEBI:15339		small molecule
FAD(3-)
CHEBI:57692		cofactor
magnesium(2+)
CHEBI:18420		cofactor
iron cation
CHEBI:24875		cofactor
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9		molecular activityleft to right
4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257		molecular activityleft to right
3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28		molecular activityleft to right
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction
WikiPathways:WP287/id55520bdd		molecular activityleft to right
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b		molecular activityleft to right
2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4		molecular activityleft to right
3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80		molecular activityleft to right
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e		molecular activityleft to right

Mechanistic edges

Mechanistic edges and their cited evidence
SubjectPredicate and descriptionObjectEvidence
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61472		consumes

2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9
  • WikiPathways:WP287

    Source assertion: GPML id1105b8d9 connects normalized CHEBI:61472 as an input of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='id1105b8d9']/Graphics; /Pathway/DataNode[@GraphId='f8109']
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9		produces

6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61473
  • WikiPathways:WP287

    Source assertion: GPML id1105b8d9 connects normalized CHEBI:61473 as an output of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='id1105b8d9']/Graphics; /Pathway/DataNode[@GraphId='ae06e']
4-hydroxybenzoate
CHEBI:30763		consumes

4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257
  • WikiPathways:WP287

    Source assertion: GPML id46b5e257 connects normalized CHEBI:30763 as an input of interaction id46b5e257.

    Source location/Pathway/Interaction[@GraphId='id46b5e257']/Graphics; /Pathway/DataNode[@GraphId='b9cc2']
4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257		produces

3-hexaprenyl-4-hydroxybenzoate
CHEBI:84492
  • WikiPathways:WP287

    Source assertion: GPML id46b5e257 connects normalized CHEBI:84492 as an output of interaction id46b5e257.

    Source location/Pathway/Interaction[@GraphId='id46b5e257']/Graphics; /Pathway/DataNode[@GraphId='f13a3']
3-hexaprenyl-4-hydroxybenzoate
CHEBI:84492		consumes

3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28
  • WikiPathways:WP287

    Source assertion: GPML id4c332e28 connects normalized CHEBI:84492 as an input of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id4c332e28']/Graphics; /Pathway/DataNode[@GraphId='f13a3']
3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28		produces

3,4-dihydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:58373
  • WikiPathways:WP287

    Source assertion: GPML id4c332e28 connects normalized CHEBI:58373 as an output of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id4c332e28']/Graphics; /Pathway/DataNode[@GraphId='b725a']
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:57916		consumes

3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction
WikiPathways:WP287/id55520bdd
  • WikiPathways:WP287

    Source assertion: GPML id55520bdd connects normalized CHEBI:57916 as an input of interaction id55520bdd.

    Source location/Pathway/Interaction[@GraphId='id55520bdd']/Graphics; /Pathway/DataNode[@GraphId='ca84f']
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction
WikiPathways:WP287/id55520bdd		produces

2-hexaprenyl-6-methoxyphenol
CHEBI:1109
  • WikiPathways:WP287

    Source assertion: GPML id55520bdd connects normalized CHEBI:1109 as an output of interaction id55520bdd.

    Source location/Pathway/Interaction[@GraphId='id55520bdd']/Graphics; /Pathway/DataNode[@GraphId='aff04']
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:58373		consumes

3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b
  • WikiPathways:WP287

    Source assertion: GPML id646fb25b connects normalized CHEBI:58373 as an input of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='id646fb25b']/Graphics; /Pathway/DataNode[@GraphId='b725a']
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b		produces

3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate
CHEBI:57916
  • WikiPathways:WP287

    Source assertion: GPML id646fb25b connects normalized CHEBI:57916 as an output of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='id646fb25b']/Graphics; /Pathway/DataNode[@GraphId='ca84f']
2-hexaprenyl-6-methoxyphenol
CHEBI:1109		consumes

2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4
  • WikiPathways:WP287

    Source assertion: GPML id74367dd4 connects normalized CHEBI:1109 as an input of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id74367dd4']/Graphics; /Pathway/DataNode[@GraphId='aff04']
2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4		produces

2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61472
  • WikiPathways:WP287

    Source assertion: GPML id74367dd4 connects normalized CHEBI:61472 as an output of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id74367dd4']/Graphics; /Pathway/DataNode[@GraphId='f8109']
3-demethylubiquinol-6
CHEBI:64253		consumes

3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80
  • WikiPathways:WP287

    Source assertion: GPML id86d34e80 connects normalized CHEBI:64253 as an input of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id86d34e80']/Graphics; /Pathway/DataNode[@GraphId='e611b']
3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80		produces

ubiquinol-6
CHEBI:52970
  • WikiPathways:WP287

    Source assertion: GPML id86d34e80 connects normalized CHEBI:52970 as an output of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id86d34e80']/Graphics; /Pathway/DataNode[@GraphId='c6f']
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol
CHEBI:61473		consumes

6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e
  • WikiPathways:WP287

    Source assertion: GPML idac01794e connects normalized CHEBI:61473 as an input of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='idac01794e']/Graphics; /Pathway/DataNode[@GraphId='ae06e']
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e		produces

3-demethylubiquinol-6
CHEBI:64253
  • WikiPathways:WP287

    Source assertion: GPML idac01794e connects normalized CHEBI:64253 as an output of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='idac01794e']/Graphics; /Pathway/DataNode[@GraphId='e611b']
hydron
CHEBI:15378		consumes

3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction
WikiPathways:WP287/id55520bdd
  • WikiPathways:WP287

    Source assertion: GPML id1cd7c8ca connects normalized CHEBI:15378 as an input of interaction id55520bdd.

    Source location/Pathway/Interaction[@GraphId='id1cd7c8ca']/Graphics; /Pathway/DataNode[@GraphId='b03a6']
2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4		produces

NADP(3-)
CHEBI:58349
  • WikiPathways:WP287

    Source assertion: GPML id20ea8209 connects normalized CHEBI:58349 as an output of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id20ea8209']/Graphics; /Pathway/DataNode[@GraphId='f5dc0']
2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4		produces

water
CHEBI:15377
  • WikiPathways:WP287

    Source assertion: GPML id20ea8209 connects normalized CHEBI:15377 as an output of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id20ea8209']/Graphics; /Pathway/DataNode[@GraphId='a40ba']
COQ6
SGD:S000003487		catalyzes

2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4
  • WikiPathways:WP287

    Source assertion: GPML id2a2637f6 connects normalized SGD:S000003487 as a catalyst of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id2a2637f6']/Graphics; /Pathway/DataNode[@GraphId='a9a']
S-adenosyl-L-methionine zwitterion
CHEBI:59789		consumes

3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b
  • WikiPathways:WP287

    Source assertion: GPML id2b26e18c connects normalized CHEBI:59789 as an input of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='id2b26e18c']/Graphics; /Pathway/DataNode[@GraphId='e06c8']
S-adenosyl-L-methionine zwitterion
CHEBI:59789		consumes

3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80
  • WikiPathways:WP287

    Source assertion: GPML id2dd44a25 connects normalized CHEBI:59789 as an input of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id2dd44a25']/Graphics; /Pathway/DataNode[@GraphId='a9290']
COQ6
SGD:S000003487		catalyzes

3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28
  • WikiPathways:WP287

    Source assertion: GPML id3498e219 connects normalized SGD:S000003487 as a catalyst of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id3498e219']/Graphics; /Pathway/DataNode[@GraphId='f061c']
hydrogen donor
CHEBI:17499		consumes

6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e
  • WikiPathways:WP287

    Source assertion: GPML id55f10a3 connects normalized CHEBI:17499 as an input of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='id55f10a3']/Graphics; /Pathway/DataNode[@GraphId='daca3']
dioxygen
CHEBI:15379		consumes

6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e
  • WikiPathways:WP287

    Source assertion: GPML id55f10a3 connects normalized CHEBI:15379 as an input of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='id55f10a3']/Graphics; /Pathway/DataNode[@GraphId='e9b89']
all-trans-hexaprenyl diphosphate(3-)
CHEBI:58179		consumes

4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257
  • WikiPathways:WP287

    Source assertion: GPML id56a4dcf9 connects normalized CHEBI:58179 as an input of interaction id46b5e257.

    Source location/Pathway/Interaction[@GraphId='id56a4dcf9']/Graphics; /Pathway/DataNode[@GraphId='ac7c1']
dioxygen
CHEBI:15379		consumes

3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28
  • WikiPathways:WP287

    Source assertion: GPML id5775a183 connects normalized CHEBI:15379 as an input of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id5775a183']/Graphics; /Pathway/DataNode[@GraphId='fa6af']
hydron
CHEBI:15378		consumes

3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28
  • WikiPathways:WP287

    Source assertion: GPML id5775a183 connects normalized CHEBI:15378 as an input of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id5775a183']/Graphics; /Pathway/DataNode[@GraphId='e5334']
hydron
CHEBI:15378		consumes

2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4
  • WikiPathways:WP287

    Source assertion: GPML id58dff702 connects normalized CHEBI:15378 as an input of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id58dff702']/Graphics; /Pathway/DataNode[@GraphId='c99ad']
NADPH(4-)
CHEBI:57783		consumes

2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4
  • WikiPathways:WP287

    Source assertion: GPML id58dff702 connects normalized CHEBI:57783 as an input of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id58dff702']/Graphics; /Pathway/DataNode[@GraphId='c718e']
dioxygen
CHEBI:15379		consumes

2-hexaprenyl-6-methoxyphenol to 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id74367dd4
  • WikiPathways:WP287

    Source assertion: GPML id58dff702 connects normalized CHEBI:15379 as an input of interaction id74367dd4.

    Source location/Pathway/Interaction[@GraphId='id58dff702']/Graphics; /Pathway/DataNode[@GraphId='c2a0a']
COQ3
SGD:S000005456		catalyzes

3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80
  • WikiPathways:WP287

    Source assertion: GPML id5d515d46 connects normalized SGD:S000005456 as a catalyst of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id5d515d46']/Graphics; /Pathway/DataNode[@GraphId='f94']
3-hexaprenyl-4-hydroxybenzoate to 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id4c332e28		produces

water
CHEBI:15377
  • WikiPathways:WP287

    Source assertion: GPML id65cb6048 connects normalized CHEBI:15377 as an output of interaction id4c332e28.

    Source location/Pathway/Interaction[@GraphId='id65cb6048']/Graphics; /Pathway/DataNode[@GraphId='f6167']
COQ2
SGD:S000005324		catalyzes

4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257
  • WikiPathways:WP287

    Source assertion: GPML id6ba28781 connects normalized SGD:S000005324 as a catalyst of interaction id46b5e257.

    Source location/Pathway/Interaction[@GraphId='id6ba28781']/Graphics; /Pathway/DataNode[@GraphId='c77']
3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80		produces

S-adenosyl-L-homocysteine zwitterion
CHEBI:57856
  • WikiPathways:WP287

    Source assertion: GPML id7872d0a9 connects normalized CHEBI:57856 as an output of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id7872d0a9']/Graphics; /Pathway/DataNode[@GraphId='e5d57']
3-demethylubiquinol-6 to ubiquinol-6 GPML interaction
WikiPathways:WP287/id86d34e80		produces

hydron
CHEBI:15378
  • WikiPathways:WP287

    Source assertion: GPML id7872d0a9 connects normalized CHEBI:15378 as an output of interaction id86d34e80.

    Source location/Pathway/Interaction[@GraphId='id7872d0a9']/Graphics; /Pathway/DataNode[@GraphId='f7037']
COQ3
SGD:S000005456		catalyzes

3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b
  • WikiPathways:WP287

    Source assertion: GPML id79c3d548 connects normalized SGD:S000005456 as a catalyst of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='id79c3d548']/Graphics; /Pathway/DataNode[@GraphId='ab9']
CAT5
SGD:S000005651		catalyzes

6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e
  • WikiPathways:WP287

    Source assertion: GPML id7c4a96b5 connects normalized SGD:S000005651 as a catalyst of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='id7c4a96b5']/Graphics; /Pathway/DataNode[@GraphId='d8e']
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9		produces

S-adenosyl-L-homocysteine zwitterion
CHEBI:57856
  • WikiPathways:WP287

    Source assertion: GPML id8e1968ee connects normalized CHEBI:57856 as an output of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='id8e1968ee']/Graphics; /Pathway/DataNode[@GraphId='bc043']
2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9		produces

hydron
CHEBI:15378
  • WikiPathways:WP287

    Source assertion: GPML id8e1968ee connects normalized CHEBI:15378 as an output of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='id8e1968ee']/Graphics; /Pathway/DataNode[@GraphId='b4452']
S-adenosyl-L-methionine zwitterion
CHEBI:59789		consumes

2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9
  • WikiPathways:WP287

    Source assertion: GPML ida32188de connects normalized CHEBI:59789 as an input of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='ida32188de']/Graphics; /Pathway/DataNode[@GraphId='ebc42']
3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate to 2-hexaprenyl-6-methoxyphenol GPML interaction
WikiPathways:WP287/id55520bdd		produces

carbon dioxide
CHEBI:16526
  • WikiPathways:WP287

    Source assertion: GPML idaa021088 connects normalized CHEBI:16526 as an output of interaction id55520bdd.

    Source location/Pathway/Interaction[@GraphId='idaa021088']/Graphics; /Pathway/DataNode[@GraphId='fef77']
4-hydroxybenzoate to 3-hexaprenyl-4-hydroxybenzoate GPML interaction
WikiPathways:WP287/id46b5e257		produces

diphosphate(3-)
CHEBI:33019
  • WikiPathways:WP287

    Source assertion: GPML idb548d439 connects normalized CHEBI:33019 as an output of interaction id46b5e257.

    Source location/Pathway/Interaction[@GraphId='idb548d439']/Graphics; /Pathway/DataNode[@GraphId='d77']
COQ5
SGD:S000004578		catalyzes

2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol to 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol GPML interaction
WikiPathways:WP287/id1105b8d9
  • WikiPathways:WP287

    Source assertion: GPML idc2f01468 connects normalized SGD:S000004578 as a catalyst of interaction id1105b8d9.

    Source location/Pathway/Interaction[@GraphId='idc2f01468']/Graphics; /Pathway/DataNode[@GraphId='de1']
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e		produces

acceptor
CHEBI:15339
  • WikiPathways:WP287

    Source assertion: GPML idf1b486b8 connects normalized CHEBI:15339 as an output of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='idf1b486b8']/Graphics; /Pathway/DataNode[@GraphId='fc22f']
6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol to 3-demethylubiquinol-6 GPML interaction
WikiPathways:WP287/idac01794e		produces

water
CHEBI:15377
  • WikiPathways:WP287

    Source assertion: GPML idf1b486b8 connects normalized CHEBI:15377 as an output of interaction idac01794e.

    Source location/Pathway/Interaction[@GraphId='idf1b486b8']/Graphics; /Pathway/DataNode[@GraphId='e7e6e']
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b		produces

S-adenosyl-L-homocysteine zwitterion
CHEBI:57856
  • WikiPathways:WP287

    Source assertion: GPML idffbd7493 connects normalized CHEBI:57856 as an output of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='idffbd7493']/Graphics; /Pathway/DataNode[@GraphId='e120c']
3,4-dihydroxy-5-all-trans-hexaprenylbenzoate to 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate GPML interaction
WikiPathways:WP287/id646fb25b		produces

hydron
CHEBI:15378
  • WikiPathways:WP287

    Source assertion: GPML idffbd7493 connects normalized CHEBI:15378 as an output of interaction id646fb25b.

    Source location/Pathway/Interaction[@GraphId='idffbd7493']/Graphics; /Pathway/DataNode[@GraphId='d056a']
COQ6
SGD:S000003487		has_cofactor

UniProtKB reviewed (Swiss-Prot) annotation. Reviewed source qualification: The caution limits deamination in other taxa and does not negate the yeast FAD cofactor annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03193); ECO:0000269 (PubMed:26808124)

FAD(3-)
CHEBI:57692
  • UniProtKB:P53318

    Source assertion: UniProtKB:P53318 annotates CHEBI:57692 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2200/comments/0/cofactors/0
  • UniProtKB:P53318

    Source assertion: UniProtKB:P53318 has the exact SGD cross-reference SGD:S000003487.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2200/uniProtKBCrossReferences/0
COQ3
SGD:S000005456		has_cofactor

UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03190)

magnesium(2+)
CHEBI:18420
  • UniProtKB:P27680

    Source assertion: UniProtKB:P27680 annotates CHEBI:18420 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/767/comments/0/cofactors/0
  • UniProtKB:P27680

    Source assertion: UniProtKB:P27680 has the exact SGD cross-reference SGD:S000005456.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/767/uniProtKBCrossReferences/0
COQ2
SGD:S000005324		has_cofactor

UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03189); ECO:0000269 (PubMed:1740455)

magnesium(2+)
CHEBI:18420
  • UniProtKB:P32378

    Source assertion: UniProtKB:P32378 annotates CHEBI:18420 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/3413/comments/0/cofactors/0
  • UniProtKB:P32378

    Source assertion: UniProtKB:P32378 has the exact SGD cross-reference SGD:S000005324.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/3413/uniProtKBCrossReferences/0
CAT5
SGD:S000005651		has_cofactor

UniProtKB reviewed (Swiss-Prot) annotation. Reviewed source qualification: Carbon catabolite repression was an indirect phenotype, not the enzyme function; retain the inferred iron cofactor annotation without adding regulatory causality. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03194) Binds 2 iron ions per subunit. UniProt note evidence: ECO:0000255 (HAMAP-Rule:MF_03194)

iron cation
CHEBI:24875
  • UniProtKB:P41735

    Source assertion: UniProtKB:P41735 annotates CHEBI:24875 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/1807/comments/0/cofactors/0; /results/1807/comments/0/note
  • UniProtKB:P41735

    Source assertion: UniProtKB:P41735 has the exact SGD cross-reference SGD:S000005651.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/1807/uniProtKBCrossReferences/0

References

Curation history