Acetogenesis

WikiPathways:WP5019

Acetogenesis is a carbon fixation and fermentation pathway in Acetobacterium woodii that reduces carbon dioxide to formate, carries the methyl branch through tetrahydrofolate intermediates, produces carbon monoxide on the carbonyl branch, and forms acetate through acetyl-CoA and acetyl phosphate. The corrinoid-mediated methyl transfer and carbonyl condensation are represented as one aggregate assembly step, with no free methyl-radical intermediate.

Pathway type
acetogenesis
Organism scope

Read the source YAML

Pathway network

55 nodes · 60 asserted directed edges

Arrows show recorded subject → object relationships, not necessarily metabolic flow. Select a node for details or an arrow for evidence. Scroll, zoom or find a node to explore.

Pathway network: Acetogenesis 55 nodes · 60 asserted directed edges. Every arrow links to its evidence table row; nodes link to their component details. Isolated declared components are retained. CHEBI:15350 — consumes → WikiPathways:WP5019/e7431; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/e7431 — produces → CHEBI:30089; Evidence: WikiPathways:WP5019produces CHEBI:15638 — consumes → WikiPathways:WP5019/id192c7b4a; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/id192c7b4a — produces → CHEBI:1989; Evidence: WikiPathways:WP5019produces CHEBI:16526 — consumes → WikiPathways:WP5019/id48aa4469; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/id48aa4469 — produces → CHEBI:17245; Evidence: WikiPathways:WP5019produces CHEBI:15351 — consumes → WikiPathways:WP5019/id48bab90b; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/id48bab90b — produces → CHEBI:15350; Evidence: WikiPathways:WP5019produces CHEBI:17908 — consumes → WikiPathways:WP5019/id4f3af248; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/id4f3af248 — produces → CHEBI:17513; Evidence: WikiPathways:WP5019produces CHEBI:15637 — consumes → WikiPathways:WP5019/id59fbd0e3; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/id59fbd0e3 — produces → CHEBI:15638; Evidence: WikiPathways:WP5019produces CHEBI:57540 — consumes → WikiPathways:WP5019/idb70e2922; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/idb70e2922 — produces → CHEBI:16908; Evidence: WikiPathways:WP5019produces CHEBI:15740 — consumes → WikiPathways:WP5019/idcb0cc195; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/idcb0cc195 — produces → CHEBI:15637; Evidence: WikiPathways:WP5019produces CHEBI:1989 — consumes → WikiPathways:WP5019/ide2e37f0; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/ide2e37f0 — produces → CHEBI:15641; Evidence: WikiPathways:WP5019produces CHEBI:17245 — consumes → WikiPathways:WP5019/ideb932d04; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/ideb932d04 — produces → CHEBI:15351; Evidence: WikiPathways:WP5019produces CHEBI:16526 — consumes → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/idee9950c3 — produces → CHEBI:15740; Evidence: WikiPathways:WP5019produces CHEBI:18276 — consumes → WikiPathways:WP5019/idf6f6d75; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/idf6f6d75 — produces → CHEBI:15378; Evidence: WikiPathways:WP5019produces WikiPathways:WP5019/e7431 — produces → CHEBI:30616; Evidence: WikiPathways:WP5019produces WikiPathways:WP5019/id48aa4469 — produces → CHEBI:17908; Evidence: WikiPathways:WP5019produces UniProtKB:H6LJY6 — catalyzes → WikiPathways:WP5019/id48bab90b; Evidence: WikiPathways:WP5019catalyzes WikiPathways:WP5019/ide2e37f0 — produces → CHEBI:57540; Evidence: WikiPathways:WP5019produces WikiPathways:WP5019/idcb0cc195 — produces → CHEBI:43474; Evidence: WikiPathways:WP5019produces UniProtKB:H6LB59 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019enables UniProtKB:H6LB60 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019enables UniProtKB:H6LB64 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019, WikiPathways:WP5019enables UniProtKB:H6LB65 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019, WikiPathways:WP5019enables UniProtKB:H6LFG4 — catalyzes → WikiPathways:WP5019/idb70e2922; Evidence: WikiPathways:WP5019catalyzes UniProtKB:H6LFG3 — catalyzes → WikiPathways:WP5019/idf6f6d75; Evidence: WikiPathways:WP5019catalyzes WikiPathways:WP5019/id48bab90b — produces → CHEBI:15346; Evidence: WikiPathways:WP5019produces UniProtKB:H6LBE7 — catalyzes → WikiPathways:WP5019/e7431; Evidence: WikiPathways:WP5019catalyzes WikiPathways:WP5019/id192c7b4a — produces → CHEBI:57540; Evidence: WikiPathways:WP5019produces UniProtKB:H6LB62 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019enables UniProtKB:H6LB61 — enables → WikiPathways:WP5019/idee9950c3; Evidence: WikiPathways:WP5019enables UniProtKB:H6LFG4 — catalyzes → WikiPathways:WP5019/id4f3af248; Evidence: WikiPathways:WP5019catalyzes WikiPathways:WP5019/idee9950c3 — produces → CHEBI:15378; Evidence: WikiPathways:WP5019produces WikiPathways:WP5019/idcb0cc195 — produces → CHEBI:456216; Evidence: WikiPathways:WP5019produces UniProtKB:H6LBX5 — catalyzes → WikiPathways:WP5019/id59fbd0e3; Evidence: WikiPathways:WP5019catalyzes UniProtKB:H6LBX4 — catalyzes → WikiPathways:WP5019/idcb0cc195; Evidence: WikiPathways:WP5019catalyzes UniProtKB:H6LBX6 — catalyzes → WikiPathways:WP5019/id192c7b4a; Evidence: WikiPathways:WP5019catalyzes UniProtKB:H6LD21 — catalyzes → WikiPathways:WP5019/id48aa4469; Evidence: WikiPathways:WP5019catalyzes CHEBI:17513 — consumes → WikiPathways:WP5019/id48aa4469; Evidence: WikiPathways:WP5019consumes CHEBI:15641 — consumes → WikiPathways:WP5019/ideb932d04; Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.; Evidence: WikiPathways:WP5019consumes CHEBI:15346 — consumes → WikiPathways:WP5019/ideb932d04; Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.; Evidence: WikiPathways:WP5019consumes WikiPathways:WP5019/ideb932d04 — produces → CHEBI:20506; Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.; Evidence: WikiPathways:WP5019produces UniProtKB:H6LD20 — enables → WikiPathways:WP5019/ideb932d04; Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.; Evidence: WikiPathways:WP5019enables UniProtKB:H6LD23 — enables → WikiPathways:WP5019/ideb932d04; Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.; Evidence: WikiPathways:WP5019enables UniProtKB:H6LD18 — enables → WikiPathways:WP5019/ideb932d04; Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.; Evidence: WikiPathways:WP5019enables UniProtKB:H6LD19 — enables → WikiPathways:WP5019/ideb932d04; Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.; Evidence: WikiPathways:WP5019enables UniProtKB:H6LD21 — has_cofactor → CHEBI:49883; UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00001966); Evidence: UniProtKB:H6LD21has cofactor UniProtKB:H6LFG3 — has_cofactor → CHEBI:190135; UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00034078); Evidence: UniProtKB:H6LFG3has cofactor UniProtKB:H6LFG3 — has_cofactor → CHEBI:49883; UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00001966); Evidence: UniProtKB:H6LFG3has cofactor UniProtKB:H6LBE7 — has_cofactor → CHEBI:18420; UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (HAMAP-Rule:MF_00020) Mg(2+). Can also accept Mn(2+). UniProt note evidence: ECO:0000256 (HAMAP-Rule:MF_00020); Evidence: UniProtKB:H6LBE7has cofactor UniProtKB:H6LBE7 — has_cofactor → CHEBI:29035; UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (HAMAP-Rule:MF_00020) Mg(2+). Can also accept Mn(2+). UniProt note evidence: ECO:0000256 (HAMAP-Rule:MF_00020); Evidence: UniProtKB:H6LBE7has cofactor formate; CHEBI:15740; Declared type: small_molecule small molecule formate ATP(4-); CHEBI:30616; Declared type: small_molecule small molecule ATP(4-) H(+); CHEBI:15378; Declared type: small_molecule small molecule H(+) 5-methyltetrahydrofolate; CHEBI:15641; Declared type: small_molecule small molecule 5-methyltetrahydrofolate FdhF1; UniProtKB:H6LB59; Declared type: protein protein FdhF1 Fhs1; UniProtKB:H6LBX4; Declared type: protein protein Fhs1 coenzyme A; CHEBI:15346; Declared type: small_molecule small molecule coenzyme A ADP(3-); CHEBI:456216; Declared type: small_molecule small molecule ADP(3-) HycB2; UniProtKB:H6LB62; Declared type: protein protein HycB2 5,10-methylenetetrahydrofolate; CHEBI:1989; Declared type: small_molecule small molecule 5,10- methylenetetrahydrofolate HycB1; UniProtKB:H6LB60; Declared type: protein protein HycB1 dihydrogen; CHEBI:18276; Declared type: small_molecule small molecule dihydrogen acetate; CHEBI:30089; Declared type: small_molecule small molecule acetate carbon dioxide; CHEBI:16526; Declared type: small_molecule small molecule carbon dioxide carbon monoxide; CHEBI:17245; Declared type: small_molecule small molecule carbon monoxide AcsA; UniProtKB:H6LD21; Declared type: protein protein AcsA 5,10-methenyltetrahydrofolate; CHEBI:15638; Declared type: small_molecule small molecule 5,10- methenyltetrahydrofolate HydA1; UniProtKB:H6LFG3; Declared type: protein protein HydA1 HycB3; UniProtKB:H6LB64; Declared type: protein protein HycB3 10-formyltetrahydrofolate; CHEBI:15637; Declared type: small_molecule small molecule 10-formyltetrahydrofolate 5,6,7,8-tetrahydrofolic acid; CHEBI:20506; Declared type: small_molecule small molecule 5,6,7,8-tetrahydrofolic acid hydrogenphosphate; CHEBI:43474; Declared type: small_molecule small molecule hydrogenphosphate acetyl-CoA; CHEBI:15351; Declared type: small_molecule small molecule acetyl-CoA HydA2; UniProtKB:H6LB65; Declared type: protein protein HydA2 HydB; UniProtKB:H6LFG4; Declared type: protein protein HydB FdhF2; UniProtKB:H6LB61; Declared type: protein protein FdhF2 NADH; CHEBI:16908; Declared type: small_molecule small molecule NADH NAD(+); CHEBI:57540; Declared type: small_molecule small molecule NAD(+) oxidized ferredoxin; CHEBI:17908; Declared type: small_molecule small molecule oxidized ferredoxin reduced ferredoxin; CHEBI:17513; Declared type: small_molecule small molecule reduced ferredoxin FolD; UniProtKB:H6LBX6; Declared type: protein protein FolD FchA; UniProtKB:H6LBX5; Declared type: protein protein FchA AcsE; UniProtKB:H6LD20; Declared type: protein protein AcsE AcsD; UniProtKB:H6LD18; Declared type: protein protein AcsD AcsC; UniProtKB:H6LD19; Declared type: protein protein AcsC AcsB1; UniProtKB:H6LD23; Declared type: protein protein AcsB1 Pta; UniProtKB:H6LJY6; Declared type: protein protein Pta acetyl phosphate; CHEBI:15350; Declared type: small_molecule small molecule acetyl phosphate AckA; UniProtKB:H6LBE7; Declared type: protein protein AckA tetra-mu3-sulfido-tetrairon; CHEBI:49883; Declared type: cofactor cofactor tetra-mu3-sulfido-tetrairon di-mu-sulfido-diiron; CHEBI:190135; Declared type: cofactor cofactor di-mu-sulfido-diiron magnesium(2+); CHEBI:18420; Declared type: cofactor cofactor magnesium(2+) manganese(2+); CHEBI:29035; Declared type: cofactor cofactor manganese(2+) acetyl phosphate to acetate GPML interaction; WikiPathways:WP5019/e7431; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity acetyl phosphate to acetate GPML interaction 5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction; WikiPathways:WP5019/id192c7b4a; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 5,10- methenyltetrahydrofolate to 5,10- methylenetetrahydrofolate GPML interaction carbon dioxide to carbon monoxide GPML interaction; WikiPathways:WP5019/id48aa4469; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity carbon dioxide to carbon monoxide GPML interaction acetyl-CoA to acetyl phosphate GPML interaction; WikiPathways:WP5019/id48bab90b; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity acetyl-CoA to acetyl phosphate GPML interaction oxidized ferredoxin reduction GPML interaction; WikiPathways:WP5019/id4f3af248; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity oxidized ferredoxin reduction GPML interaction 10-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate GPML interaction; WikiPathways:WP5019/id59fbd0e3; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 10-formyltetrahydrofolate to 5,10- methenyltetrahydrofolate GPML interaction NADH production GPML interaction; WikiPathways:WP5019/idb70e2922; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity NADH production GPML interaction formate to 10-formyltetrahydrofolate GPML interaction; WikiPathways:WP5019/idcb0cc195; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity formate to 10-formyltetrahydrofolate GPML interaction 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction; WikiPathways:WP5019/ide2e37f0; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate); WikiPathways:WP5019/ideb932d04; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate) carbon dioxide to formate GPML interaction; WikiPathways:WP5019/idee9950c3; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity carbon dioxide to formate GPML interaction dihydrogen to proton GPML interaction; WikiPathways:WP5019/idf6f6d75; Declared type: molecular_activity; Source reaction direction: left_to_right molecular activity dihydrogen to proton GPML interaction

Components and activities

Declared biological components and source reaction directions
NodeKind or roleSource direction
Acetobacterium woodii
NCBITaxon:33952		taxon
formate
CHEBI:15740		small molecule
ATP(4-)
CHEBI:30616		small molecule
H(+)
CHEBI:15378		small molecule
5-methyltetrahydrofolate
CHEBI:15641		small molecule
FdhF1
UniProtKB:H6LB59		protein
Fhs1
UniProtKB:H6LBX4		protein
coenzyme A
CHEBI:15346		small molecule
ADP(3-)
CHEBI:456216		small molecule
HycB2
UniProtKB:H6LB62		protein
5,10-methylenetetrahydrofolate
CHEBI:1989		small molecule
HycB1
UniProtKB:H6LB60		protein
dihydrogen
CHEBI:18276		small molecule
acetate
CHEBI:30089		small molecule
carbon dioxide
CHEBI:16526		small molecule
carbon monoxide
CHEBI:17245		small molecule
AcsA
UniProtKB:H6LD21		protein
5,10-methenyltetrahydrofolate
CHEBI:15638		small molecule
HydA1
UniProtKB:H6LFG3		protein
HycB3
UniProtKB:H6LB64		protein
10-formyltetrahydrofolate
CHEBI:15637		small molecule
5,6,7,8-tetrahydrofolic acid
CHEBI:20506		small molecule
hydrogenphosphate
CHEBI:43474		small molecule
acetyl-CoA
CHEBI:15351		small molecule
HydA2
UniProtKB:H6LB65		protein
HydB
UniProtKB:H6LFG4		protein
FdhF2
UniProtKB:H6LB61		protein
NADH
CHEBI:16908		small molecule
NAD(+)
CHEBI:57540		small molecule
oxidized ferredoxin
CHEBI:17908		small molecule
reduced ferredoxin
CHEBI:17513		small molecule
FolD
UniProtKB:H6LBX6		protein
FchA
UniProtKB:H6LBX5		protein
AcsE
UniProtKB:H6LD20		protein
AcsD
UniProtKB:H6LD18		protein
AcsC
UniProtKB:H6LD19		protein
AcsB1
UniProtKB:H6LD23		protein
Pta
UniProtKB:H6LJY6		protein
acetyl phosphate
CHEBI:15350		small molecule
AckA
UniProtKB:H6LBE7		protein
tetra-mu3-sulfido-tetrairon
CHEBI:49883		cofactor
di-mu-sulfido-diiron
CHEBI:190135		cofactor
magnesium(2+)
CHEBI:18420		cofactor
manganese(2+)
CHEBI:29035		cofactor
acetyl phosphate to acetate GPML interaction
WikiPathways:WP5019/e7431		molecular activityleft to right
5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction
WikiPathways:WP5019/id192c7b4a		molecular activityleft to right
carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469		molecular activityleft to right
acetyl-CoA to acetyl phosphate GPML interaction
WikiPathways:WP5019/id48bab90b		molecular activityleft to right
oxidized ferredoxin reduction GPML interaction
WikiPathways:WP5019/id4f3af248		molecular activityleft to right
10-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate GPML interaction
WikiPathways:WP5019/id59fbd0e3		molecular activityleft to right
NADH production GPML interaction
WikiPathways:WP5019/idb70e2922		molecular activityleft to right
formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195		molecular activityleft to right
5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction
WikiPathways:WP5019/ide2e37f0		molecular activityleft to right
Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04		molecular activityleft to right
carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3		molecular activityleft to right
dihydrogen to proton GPML interaction
WikiPathways:WP5019/idf6f6d75		molecular activityleft to right

Mechanistic edges

Mechanistic edges and their cited evidence
SubjectPredicate and descriptionObjectEvidence
acetyl phosphate
CHEBI:15350		consumes

acetyl phosphate to acetate GPML interaction
WikiPathways:WP5019/e7431
  • WikiPathways:WP5019

    Source assertion: GPML e7431 connects normalized CHEBI:15350 as an input of interaction e7431.

    Source location/Pathway/Interaction[@GraphId='e7431']/Graphics; /Pathway/DataNode[@GraphId='b4740']
acetyl phosphate to acetate GPML interaction
WikiPathways:WP5019/e7431		produces

acetate
CHEBI:30089
  • WikiPathways:WP5019

    Source assertion: GPML e7431 connects normalized CHEBI:30089 as an output of interaction e7431.

    Source location/Pathway/Interaction[@GraphId='e7431']/Graphics; /Pathway/DataNode[@GraphId='d0ddf']
5,10-methenyltetrahydrofolate
CHEBI:15638		consumes

5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction
WikiPathways:WP5019/id192c7b4a
  • WikiPathways:WP5019

    Source assertion: GPML id192c7b4a connects normalized CHEBI:15638 as an input of interaction id192c7b4a.

    Source location/Pathway/Interaction[@GraphId='id192c7b4a']/Graphics; /Pathway/DataNode[@GraphId='e2598']
5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction
WikiPathways:WP5019/id192c7b4a		produces

5,10-methylenetetrahydrofolate
CHEBI:1989
  • WikiPathways:WP5019

    Source assertion: GPML id192c7b4a connects normalized CHEBI:1989 as an output of interaction id192c7b4a.

    Source location/Pathway/Interaction[@GraphId='id192c7b4a']/Graphics; /Pathway/DataNode[@GraphId='c1016']
carbon dioxide
CHEBI:16526		consumes

carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469
  • WikiPathways:WP5019

    Source assertion: GPML id48aa4469 connects normalized CHEBI:16526 as an input of interaction id48aa4469.

    Source location/Pathway/Interaction[@GraphId='id48aa4469']/Graphics; /Pathway/DataNode[@GraphId='fe5e2']
carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469		produces

carbon monoxide
CHEBI:17245
  • WikiPathways:WP5019

    Source assertion: GPML id48aa4469 connects normalized CHEBI:17245 as an output of interaction id48aa4469.

    Source location/Pathway/Interaction[@GraphId='id48aa4469']/Graphics; /Pathway/DataNode[@GraphId='dcb01']
acetyl-CoA
CHEBI:15351		consumes

acetyl-CoA to acetyl phosphate GPML interaction
WikiPathways:WP5019/id48bab90b
  • WikiPathways:WP5019

    Source assertion: GPML id48bab90b connects normalized CHEBI:15351 as an input of interaction id48bab90b.

    Source location/Pathway/Interaction[@GraphId='id48bab90b']/Graphics; /Pathway/DataNode[@GraphId='f601f']
acetyl-CoA to acetyl phosphate GPML interaction
WikiPathways:WP5019/id48bab90b		produces

acetyl phosphate
CHEBI:15350
  • WikiPathways:WP5019

    Source assertion: GPML id48bab90b connects normalized CHEBI:15350 as an output of interaction id48bab90b.

    Source location/Pathway/Interaction[@GraphId='id48bab90b']/Graphics; /Pathway/DataNode[@GraphId='b4740']
oxidized ferredoxin
CHEBI:17908		consumes

oxidized ferredoxin reduction GPML interaction
WikiPathways:WP5019/id4f3af248
  • WikiPathways:WP5019

    Source assertion: GPML id4f3af248 connects normalized CHEBI:17908 as an input of interaction id4f3af248.

    Source location/Pathway/Interaction[@GraphId='id4f3af248']/Graphics; /Pathway/DataNode[@GraphId='afcfe']
oxidized ferredoxin reduction GPML interaction
WikiPathways:WP5019/id4f3af248		produces

reduced ferredoxin
CHEBI:17513
  • WikiPathways:WP5019

    Source assertion: GPML id4f3af248 connects normalized CHEBI:17513 as an output of interaction id4f3af248.

    Source location/Pathway/Interaction[@GraphId='id4f3af248']/Graphics; /Pathway/DataNode[@GraphId='f1eb8']
10-formyltetrahydrofolate
CHEBI:15637		consumes

10-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate GPML interaction
WikiPathways:WP5019/id59fbd0e3
  • WikiPathways:WP5019

    Source assertion: GPML id59fbd0e3 connects normalized CHEBI:15637 as an input of interaction id59fbd0e3.

    Source location/Pathway/Interaction[@GraphId='id59fbd0e3']/Graphics; /Pathway/DataNode[@GraphId='f0345']
10-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate GPML interaction
WikiPathways:WP5019/id59fbd0e3		produces

5,10-methenyltetrahydrofolate
CHEBI:15638
  • WikiPathways:WP5019

    Source assertion: GPML id59fbd0e3 connects normalized CHEBI:15638 as an output of interaction id59fbd0e3.

    Source location/Pathway/Interaction[@GraphId='id59fbd0e3']/Graphics; /Pathway/DataNode[@GraphId='e2598']
NAD(+)
CHEBI:57540		consumes

NADH production GPML interaction
WikiPathways:WP5019/idb70e2922
  • WikiPathways:WP5019

    Source assertion: GPML idb70e2922 connects normalized CHEBI:57540 as an input of interaction idb70e2922.

    Source location/Pathway/Interaction[@GraphId='idb70e2922']/Graphics; /Pathway/DataNode[@GraphId='fc35e']
NADH production GPML interaction
WikiPathways:WP5019/idb70e2922		produces

NADH
CHEBI:16908
  • WikiPathways:WP5019

    Source assertion: GPML idb70e2922 connects normalized CHEBI:16908 as an output of interaction idb70e2922.

    Source location/Pathway/Interaction[@GraphId='idb70e2922']/Graphics; /Pathway/DataNode[@GraphId='ac93a']
formate
CHEBI:15740		consumes

formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195
  • WikiPathways:WP5019

    Source assertion: GPML idcb0cc195 connects normalized CHEBI:15740 as an input of interaction idcb0cc195.

    Source location/Pathway/Interaction[@GraphId='idcb0cc195']/Graphics; /Pathway/DataNode[@GraphId='a4940']
formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195		produces

10-formyltetrahydrofolate
CHEBI:15637
  • WikiPathways:WP5019

    Source assertion: GPML idcb0cc195 connects normalized CHEBI:15637 as an output of interaction idcb0cc195.

    Source location/Pathway/Interaction[@GraphId='idcb0cc195']/Graphics; /Pathway/DataNode[@GraphId='f0345']
5,10-methylenetetrahydrofolate
CHEBI:1989		consumes

5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction
WikiPathways:WP5019/ide2e37f0
  • WikiPathways:WP5019

    Source assertion: GPML ide2e37f0 connects normalized CHEBI:1989 as an input of interaction ide2e37f0.

    Source location/Pathway/Interaction[@GraphId='ide2e37f0']/Graphics; /Pathway/DataNode[@GraphId='c1016']
5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction
WikiPathways:WP5019/ide2e37f0		produces

5-methyltetrahydrofolate
CHEBI:15641
  • WikiPathways:WP5019

    Source assertion: GPML ide2e37f0 connects normalized CHEBI:15641 as an output of interaction ide2e37f0.

    Source location/Pathway/Interaction[@GraphId='ide2e37f0']/Graphics; /Pathway/DataNode[@GraphId='aed66']
carbon monoxide
CHEBI:17245		consumes

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML ideb932d04 connects normalized CHEBI:17245 as an input of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='ideb932d04']/Graphics; /Pathway/DataNode[@GraphId='dcb01']
Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04		produces

acetyl-CoA
CHEBI:15351
  • WikiPathways:WP5019

    Source assertion: GPML ideb932d04 connects normalized CHEBI:15351 as an output of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='ideb932d04']/Graphics; /Pathway/DataNode[@GraphId='f601f']
carbon dioxide
CHEBI:16526		consumes

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML idee9950c3 connects normalized CHEBI:16526 as an input of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='idee9950c3']/Graphics; /Pathway/DataNode[@GraphId='dca37']
carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3		produces

formate
CHEBI:15740
  • WikiPathways:WP5019

    Source assertion: GPML idee9950c3 connects normalized CHEBI:15740 as an output of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='idee9950c3']/Graphics; /Pathway/DataNode[@GraphId='a4940']
dihydrogen
CHEBI:18276		consumes

dihydrogen to proton GPML interaction
WikiPathways:WP5019/idf6f6d75
  • WikiPathways:WP5019

    Source assertion: GPML idf6f6d75 connects normalized CHEBI:18276 as an input of interaction idf6f6d75.

    Source location/Pathway/Interaction[@GraphId='idf6f6d75']/Graphics; /Pathway/DataNode[@GraphId='b7200']
dihydrogen to proton GPML interaction
WikiPathways:WP5019/idf6f6d75		produces

H(+)
CHEBI:15378
  • WikiPathways:WP5019

    Source assertion: GPML idf6f6d75 connects normalized CHEBI:15378 as an output of interaction idf6f6d75.

    Source location/Pathway/Interaction[@GraphId='idf6f6d75']/Graphics; /Pathway/DataNode[@GraphId='e4d29']
acetyl phosphate to acetate GPML interaction
WikiPathways:WP5019/e7431		produces

ATP(4-)
CHEBI:30616
  • WikiPathways:WP5019

    Source assertion: GPML id275b32d7 connects normalized CHEBI:30616 as an output of interaction e7431.

    Source location/Pathway/Interaction[@GraphId='id275b32d7']/Graphics; /Pathway/DataNode[@GraphId='cc2f1']
carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469		produces

oxidized ferredoxin
CHEBI:17908
  • WikiPathways:WP5019

    Source assertion: GPML id2f21bbbe connects normalized CHEBI:17908 as an output of interaction id48aa4469.

    Source location/Pathway/Interaction[@GraphId='id2f21bbbe']/Graphics; /Pathway/DataNode[@GraphId='afcfe']
Pta
UniProtKB:H6LJY6		catalyzes

acetyl-CoA to acetyl phosphate GPML interaction
WikiPathways:WP5019/id48bab90b
  • WikiPathways:WP5019

    Source assertion: GPML id43d52636 connects normalized UniProtKB:H6LJY6 as a catalyst of interaction id48bab90b.

    Source location/Pathway/Interaction[@GraphId='id43d52636']/Graphics; /Pathway/DataNode[@GraphId='ede55']
5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate GPML interaction
WikiPathways:WP5019/ide2e37f0		produces

NAD(+)
CHEBI:57540
  • WikiPathways:WP5019

    Source assertion: GPML id5622490f connects normalized CHEBI:57540 as an output of interaction ide2e37f0.

    Source location/Pathway/Interaction[@GraphId='id5622490f']/Graphics; /Pathway/DataNode[@GraphId='fc35e']
formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195		produces

hydrogenphosphate
CHEBI:43474
  • WikiPathways:WP5019

    Source assertion: GPML id5767ed45 connects normalized CHEBI:43474 as an output of interaction idcb0cc195.

    Source location/Pathway/Interaction[@GraphId='id5767ed45']/Graphics; /Pathway/DataNode[@GraphId='f6014']
FdhF1
UniProtKB:H6LB59		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id58e440b7 connects normalized UniProtKB:H6LB59 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id58e440b7']/Graphics; /Pathway/DataNode[@GraphId='b132a']
HycB1
UniProtKB:H6LB60		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id58e440b7 connects normalized UniProtKB:H6LB60 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id58e440b7']/Graphics; /Pathway/DataNode[@GraphId='c8972']
HycB3
UniProtKB:H6LB64		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id58e440b7 connects normalized UniProtKB:H6LB64 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id58e440b7']/Graphics; /Pathway/DataNode[@GraphId='ed8bc']
  • WikiPathways:WP5019

    Source assertion: GPML id9ab97d5f connects normalized UniProtKB:H6LB64 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id9ab97d5f']/Graphics; /Pathway/DataNode[@GraphId='e5a95']
HydA2
UniProtKB:H6LB65		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id58e440b7 connects normalized UniProtKB:H6LB65 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id58e440b7']/Graphics; /Pathway/DataNode[@GraphId='ee690']
  • WikiPathways:WP5019

    Source assertion: GPML id9ab97d5f connects normalized UniProtKB:H6LB65 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id9ab97d5f']/Graphics; /Pathway/DataNode[@GraphId='b2df1']
HydB
UniProtKB:H6LFG4		catalyzes

NADH production GPML interaction
WikiPathways:WP5019/idb70e2922
  • WikiPathways:WP5019

    Source assertion: GPML id752f0f0e connects normalized UniProtKB:H6LFG4 as a catalyst of interaction idb70e2922.

    Source location/Pathway/Interaction[@GraphId='id752f0f0e']/Graphics; /Pathway/DataNode[@GraphId='c50df']
HydA1
UniProtKB:H6LFG3		catalyzes

dihydrogen to proton GPML interaction
WikiPathways:WP5019/idf6f6d75
  • WikiPathways:WP5019

    Source assertion: GPML id84c19ee7 connects normalized UniProtKB:H6LFG3 as a catalyst of interaction idf6f6d75.

    Source location/Pathway/Interaction[@GraphId='id84c19ee7']/Graphics; /Pathway/DataNode[@GraphId='e7d5b']
acetyl-CoA to acetyl phosphate GPML interaction
WikiPathways:WP5019/id48bab90b		produces

coenzyme A
CHEBI:15346
  • WikiPathways:WP5019

    Source assertion: GPML id8e876ee4 connects normalized CHEBI:15346 as an output of interaction id48bab90b.

    Source location/Pathway/Interaction[@GraphId='id8e876ee4']/Graphics; /Pathway/DataNode[@GraphId='baa9c']
AckA
UniProtKB:H6LBE7		catalyzes

acetyl phosphate to acetate GPML interaction
WikiPathways:WP5019/e7431
  • WikiPathways:WP5019

    Source assertion: GPML id8ed8b579 connects normalized UniProtKB:H6LBE7 as a catalyst of interaction e7431.

    Source location/Pathway/Interaction[@GraphId='id8ed8b579']/Graphics; /Pathway/DataNode[@GraphId='e5ea4']
5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction
WikiPathways:WP5019/id192c7b4a		produces

NAD(+)
CHEBI:57540
  • WikiPathways:WP5019

    Source assertion: GPML id927fb03c connects normalized CHEBI:57540 as an output of interaction id192c7b4a.

    Source location/Pathway/Interaction[@GraphId='id927fb03c']/Graphics; /Pathway/DataNode[@GraphId='fc35e']
HycB2
UniProtKB:H6LB62		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id9ab97d5f connects normalized UniProtKB:H6LB62 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id9ab97d5f']/Graphics; /Pathway/DataNode[@GraphId='bf4ae']
FdhF2
UniProtKB:H6LB61		enables

carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3
  • WikiPathways:WP5019

    Source assertion: GPML id9ab97d5f connects normalized UniProtKB:H6LB61 as an enabling enzyme component of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='id9ab97d5f']/Graphics; /Pathway/DataNode[@GraphId='c83d5']
HydB
UniProtKB:H6LFG4		catalyzes

oxidized ferredoxin reduction GPML interaction
WikiPathways:WP5019/id4f3af248
  • WikiPathways:WP5019

    Source assertion: GPML idba9e932 connects normalized UniProtKB:H6LFG4 as a catalyst of interaction id4f3af248.

    Source location/Pathway/Interaction[@GraphId='idba9e932']/Graphics; /Pathway/DataNode[@GraphId='c50df']
carbon dioxide to formate GPML interaction
WikiPathways:WP5019/idee9950c3		produces

H(+)
CHEBI:15378
  • WikiPathways:WP5019

    Source assertion: GPML idbe118003 connects normalized CHEBI:15378 as an output of interaction idee9950c3.

    Source location/Pathway/Interaction[@GraphId='idbe118003']/Graphics; /Pathway/DataNode[@GraphId='a8764']
formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195		produces

ADP(3-)
CHEBI:456216
  • WikiPathways:WP5019

    Source assertion: GPML idbf2124e2 connects normalized CHEBI:456216 as an output of interaction idcb0cc195.

    Source location/Pathway/Interaction[@GraphId='idbf2124e2']/Graphics; /Pathway/DataNode[@GraphId='bd02e']
FchA
UniProtKB:H6LBX5		catalyzes

10-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate GPML interaction
WikiPathways:WP5019/id59fbd0e3
  • WikiPathways:WP5019

    Source assertion: GPML f45ef connects normalized UniProtKB:H6LBX5 as a catalyst of interaction id59fbd0e3.

    Source location/Pathway/Interaction[@GraphId='f45ef']/Graphics; /Pathway/DataNode[@GraphId='c9408']
Fhs1
UniProtKB:H6LBX4		catalyzes

formate to 10-formyltetrahydrofolate GPML interaction
WikiPathways:WP5019/idcb0cc195
  • WikiPathways:WP5019

    Source assertion: GPML cb0d1 connects normalized UniProtKB:H6LBX4 as a catalyst of interaction idcb0cc195.

    Source location/Pathway/Interaction[@GraphId='cb0d1']/Graphics; /Pathway/DataNode[@GraphId='b6cbe']
FolD
UniProtKB:H6LBX6		catalyzes

5,10-methenyltetrahydrofolate to 5,10-methylenetetrahydrofolate GPML interaction
WikiPathways:WP5019/id192c7b4a
  • WikiPathways:WP5019

    Source assertion: GPML cffef connects normalized UniProtKB:H6LBX6 as a catalyst of interaction id192c7b4a.

    Source location/Pathway/Interaction[@GraphId='cffef']/Graphics; /Pathway/DataNode[@GraphId='c7e4d']
AcsA
UniProtKB:H6LD21		catalyzes

carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469
  • WikiPathways:WP5019

    Source assertion: GPML c0c8c connects normalized UniProtKB:H6LD21 as a catalyst of interaction id48aa4469.

    Source location/Pathway/Interaction[@GraphId='c0c8c']/Graphics; /Pathway/DataNode[@GraphId='de84f']
reduced ferredoxin
CHEBI:17513		consumes

carbon dioxide to carbon monoxide GPML interaction
WikiPathways:WP5019/id48aa4469
  • WikiPathways:WP5019

    Source assertion: GPML ad38c connects normalized CHEBI:17513 as an input of interaction id48aa4469.

    Source location/Pathway/Interaction[@GraphId='ad38c']/Graphics; /Pathway/DataNode[@GraphId='f1eb8']
5-methyltetrahydrofolate
CHEBI:15641		consumes

Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML id8e976caf connects normalized CHEBI:15641 as an input of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id8e976caf']/Graphics; /Pathway/DataNode[@GraphId='aed66']
coenzyme A
CHEBI:15346		consumes

Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML id2b845640 connects normalized CHEBI:15346 as an input of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id2b845640']/Graphics; /Pathway/DataNode[@GraphId='baa9c']
Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04		produces

Aggregate of native corrinoid-bound methyl transfer and acetyl-CoA assembly; free methyl radical is not an intermediate.

5,6,7,8-tetrahydrofolic acid
CHEBI:20506
  • WikiPathways:WP5019

    Source assertion: GPML id8e976caf connects normalized CHEBI:20506 as an output of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id8e976caf']/Graphics; /Pathway/DataNode[@GraphId='f4118']
AcsE
UniProtKB:H6LD20		enables

Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML id8e976caf connects normalized UniProtKB:H6LD20 as an enabling enzyme component of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id8e976caf']/Graphics; /Pathway/DataNode[@GraphId='b31af']
AcsB1
UniProtKB:H6LD23		enables

Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML ideb932d04 connects normalized UniProtKB:H6LD23 as an enabling enzyme component of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='ideb932d04']/Graphics; /Pathway/DataNode[@GraphId='c0d75']
AcsD
UniProtKB:H6LD18		enables

Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML id8e976caf connects normalized UniProtKB:H6LD18 as an enabling enzyme component of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id8e976caf']/Graphics; /Pathway/DataNode[@GraphId='f37ef']
AcsC
UniProtKB:H6LD19		enables

Component of the combined corrinoid methyl transfer/acetyl-CoA assembly, not an independently catalytic complex subunit.

Corrinoid-dependent methyl transfer and acetyl-CoA assembly (aggregate)
WikiPathways:WP5019/ideb932d04
  • WikiPathways:WP5019

    Source assertion: GPML id8e976caf connects normalized UniProtKB:H6LD19 as an enabling enzyme component of interaction ideb932d04.

    Source location/Pathway/Interaction[@GraphId='id8e976caf']/Graphics; /Pathway/DataNode[@GraphId='d0c8a']
AcsA
UniProtKB:H6LD21		has_cofactor

UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00001966)

tetra-mu3-sulfido-tetrairon
CHEBI:49883
  • UniProtKB:H6LD21

    Source assertion: UniProtKB:H6LD21 annotates CHEBI:49883 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=accession%3AH6LB59+OR+accession%3AH6LB60+OR+accession%3AH6LB61+OR+accession%3AH6LB62+OR+accession%3AH6LB64+OR+accession%3AH6LB65+OR+accession%3AH6LBE7+OR+accession%3AH6LBX4+OR+accession%3AH6LBX5+OR+accession%3AH6LBX6+OR+accession%3AH6LD21+OR+accession%3AH6LFG3+OR+accession%3AH6LFG4+OR+accession%3AH6LJY6+OR+accession%3AP9WJN3&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:58c69edf7b795ede960dadfaf0093c56d2e871e90536ef0184f021222ecc1321] #/results/6/comments/0/cofactors/0
HydA1
UniProtKB:H6LFG3		has_cofactor

UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00034078)

di-mu-sulfido-diiron
CHEBI:190135
  • UniProtKB:H6LFG3

    Source assertion: UniProtKB:H6LFG3 annotates CHEBI:190135 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=accession%3AH6LB59+OR+accession%3AH6LB60+OR+accession%3AH6LB61+OR+accession%3AH6LB62+OR+accession%3AH6LB64+OR+accession%3AH6LB65+OR+accession%3AH6LBE7+OR+accession%3AH6LBX4+OR+accession%3AH6LBX5+OR+accession%3AH6LBX6+OR+accession%3AH6LD21+OR+accession%3AH6LFG3+OR+accession%3AH6LFG4+OR+accession%3AH6LJY6+OR+accession%3AP9WJN3&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:58c69edf7b795ede960dadfaf0093c56d2e871e90536ef0184f021222ecc1321] #/results/7/comments/0/cofactors/0
HydA1
UniProtKB:H6LFG3		has_cofactor

UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (ARBA:ARBA00001966)

tetra-mu3-sulfido-tetrairon
CHEBI:49883
  • UniProtKB:H6LFG3

    Source assertion: UniProtKB:H6LFG3 annotates CHEBI:49883 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=accession%3AH6LB59+OR+accession%3AH6LB60+OR+accession%3AH6LB61+OR+accession%3AH6LB62+OR+accession%3AH6LB64+OR+accession%3AH6LB65+OR+accession%3AH6LBE7+OR+accession%3AH6LBX4+OR+accession%3AH6LBX5+OR+accession%3AH6LBX6+OR+accession%3AH6LD21+OR+accession%3AH6LFG3+OR+accession%3AH6LFG4+OR+accession%3AH6LJY6+OR+accession%3AP9WJN3&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:58c69edf7b795ede960dadfaf0093c56d2e871e90536ef0184f021222ecc1321] #/results/7/comments/1/cofactors/0
AckA
UniProtKB:H6LBE7		has_cofactor

UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (HAMAP-Rule:MF_00020) Mg(2+). Can also accept Mn(2+). UniProt note evidence: ECO:0000256 (HAMAP-Rule:MF_00020)

magnesium(2+)
CHEBI:18420
  • UniProtKB:H6LBE7

    Source assertion: UniProtKB:H6LBE7 annotates CHEBI:18420 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=accession%3AH6LB59+OR+accession%3AH6LB60+OR+accession%3AH6LB61+OR+accession%3AH6LB62+OR+accession%3AH6LB64+OR+accession%3AH6LB65+OR+accession%3AH6LBE7+OR+accession%3AH6LBX4+OR+accession%3AH6LBX5+OR+accession%3AH6LBX6+OR+accession%3AH6LD21+OR+accession%3AH6LFG3+OR+accession%3AH6LFG4+OR+accession%3AH6LJY6+OR+accession%3AP9WJN3&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:58c69edf7b795ede960dadfaf0093c56d2e871e90536ef0184f021222ecc1321] #/results/1/comments/0/cofactors/0; /results/1/comments/0/note
AckA
UniProtKB:H6LBE7		has_cofactor

UniProtKB unreviewed (TrEMBL) annotation. UniProt evidence: ECO:0000256 (HAMAP-Rule:MF_00020) Mg(2+). Can also accept Mn(2+). UniProt note evidence: ECO:0000256 (HAMAP-Rule:MF_00020)

manganese(2+)
CHEBI:29035
  • UniProtKB:H6LBE7

    Source assertion: UniProtKB:H6LBE7 annotates CHEBI:29035 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=accession%3AH6LB59+OR+accession%3AH6LB60+OR+accession%3AH6LB61+OR+accession%3AH6LB62+OR+accession%3AH6LB64+OR+accession%3AH6LB65+OR+accession%3AH6LBE7+OR+accession%3AH6LBX4+OR+accession%3AH6LBX5+OR+accession%3AH6LBX6+OR+accession%3AH6LD21+OR+accession%3AH6LFG3+OR+accession%3AH6LFG4+OR+accession%3AH6LJY6+OR+accession%3AP9WJN3&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:58c69edf7b795ede960dadfaf0093c56d2e871e90536ef0184f021222ecc1321] #/results/1/comments/0/cofactors/1; /results/1/comments/0/note

References

Curation history