glycolysis I (from glucose 6-phosphate)

gomodel:YeastPathways_GLYCOLYSIS

SGD glycolysis I (from glucose 6-phosphate) in Saccharomyces cerevisiae S288C links PGI1, PFK27, FBP1, FBA1, TPI1, TDH1, TDH2, TDH3, PGK1, GPM1, ENO1, ENO2, CDC19, and PYK2 activities across fructose-phosphate, triose-phosphate, phosphoglycerate, phosphoenolpyruvate, and pyruvate chemistry.

Pathway type

central carbon metabolism

Organism scope

Saccharomyces cerevisiae S288C NCBITaxon:559292

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Pathway network

56 nodes · 148 asserted directed edges

Arrows show recorded subject → object relationships, not necessarily metabolic flow. Select a node for details or an arrow for evidence. Scroll, zoom or find a node to explore.

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Components and activities

Declared biological components and source reaction directions
Node	Kind or role	Source direction
Saccharomyces cerevisiae S288C `NCBITaxon:559292`	taxon
cytosol `GO:0005829`	cellular component
GPM1 Scer `SGD:S000001635`	protein
phosphonatoenolpyruvate `CHEBI:58702`	small molecule
glycolytic process through glucose-6-phosphate `GO:0061620`	biological process
NAD(1-) `CHEBI:57540`	small molecule
FBP1 Scer `SGD:S000004369`	protein
hydrogenphosphate `CHEBI:43474`	small molecule
ADP(3-) `CHEBI:456216`	small molecule
3-phosphonato-D-glycerate(3-) `CHEBI:58272`	small molecule
PGK1 Scer `SGD:S000000605`	protein
3-phosphonato-D-glyceroyl phosphate(4-) `CHEBI:57604`	small molecule
CPX-554 Scer `SGD:S000218025`	complex
PGI1 Scer `SGD:S000000400`	protein
PYK2 Scer `SGD:S000005874`	protein
water `CHEBI:15377`	small molecule
glycerone phosphate(2-) `CHEBI:57642`	small molecule
pyruvate `CHEBI:15361`	small molecule
beta-D-fructofuranose 1,6-bisphosphate(4-) `CHEBI:32966`	small molecule
hydron `CHEBI:15378`	small molecule
ATP(4-) `CHEBI:30616`	small molecule
FBA1 Scer `SGD:S000001543`	protein
D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	small molecule
NADH(2-) `CHEBI:57945`	small molecule
2-phosphonato-D-glycerate(3-) `CHEBI:58289`	small molecule
D-glucopyranose 6-phosphate `CHEBI:4170`	small molecule
ENO1 Scer `SGD:S000003486`	protein
beta-D-fructofuranose 6-phosphate(2-) `CHEBI:57634`	small molecule
TDH1 Scer `SGD:S000003588`	protein
TDH2 Scer `SGD:S000003769`	protein
TPI1 Scer `SGD:S000002457`	protein
TDH3 Scer `SGD:S000003424`	protein
CDC19 Scer `SGD:S000000036`	protein
ENO2 Scer `SGD:S000001217`	protein
ATP-dependent 6-phosphofructokinase subunit alpha `UniProtKB:P16861`	protein
ATP-dependent 6-phosphofructokinase subunit beta `UniProtKB:P16862`	protein
cytoplasm `GO:0005737`	cellular component
mitochondrial outer membrane `GO:0005741`	cellular component
mitochondrial intermembrane space `GO:0005758`	cellular component
mitochondrion `GO:0005739`	cellular component
magnesium(2+) `CHEBI:18420`	cofactor
potassium(1+) `CHEBI:29103`	cofactor
zinc(2+) `CHEBI:29105`	cofactor
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	molecular activity
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	molecular activity
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	molecular activity
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	molecular activity
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	molecular activity
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	molecular activity
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	molecular activity
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	molecular activity
phosphoglycerate mutase activity `gomodel:RXN-15513`	molecular activity
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	molecular activity
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	molecular activity
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	molecular activity
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	molecular activity
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	molecular activity

Mechanistic edges

Mechanistic edges and their cited evidence
Subject	Predicate and description	Object	Evidence
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	provides_input_for	triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002413 gomodel:TRIOSEPISOMERIZATION-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/0; endpoint types: /individuals/28/type; /individuals/35/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 BFO:0000066 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004587. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/1; endpoint types: /individuals/124/type; /individuals/130/type`
GPM1 Scer `SGD:S000001635`	enables	phosphoglycerate mutase activity `gomodel:RXN-15513`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 RO:0002333 gomodel:YKL152C-MONOMER_RXN-15513_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/2; endpoint types: /individuals/34/type; /individuals/43/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	has_output	phosphonatoenolpyruvate `CHEBI:58702`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002234 gomodel:CHEBI_58702_2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/3; endpoint types: /individuals/110/type; /individuals/25/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/4; endpoint types: /individuals/28/type; /individuals/143/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/5; endpoint types: /individuals/34/type; /individuals/112/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/6; endpoint types: /individuals/110/type; /individuals/112/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_input	NAD(1-) `CHEBI:57540`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004607. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/7; endpoint types: /individuals/143/type; /individuals/144/type`
FBP1 Scer `SGD:S000004369`	enables	fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002333 gomodel:YLR377C-MONOMER_F16BDEPHOS-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/8; endpoint types: /individuals/29/type; /individuals/44/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_input	hydrogenphosphate `CHEBI:43474`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004581. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/9; endpoint types: /individuals/124/type; /individuals/126/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN BFO:0000066 gomodel:reaction_2PGADEHYDRAT-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/10; endpoint types: /individuals/110/type; /individuals/100/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	has_output	ADP(3-) `CHEBI:456216`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002234 gomodel:CHEBI_456216_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/11; endpoint types: /individuals/111/type; /individuals/13/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	has_output	3-phosphonato-D-glycerate(3-) `CHEBI:58272`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002234 gomodel:CHEBI_58272_PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/12; endpoint types: /individuals/33/type; /individuals/22/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	has_input	ADP(3-) `CHEBI:456216`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004638. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/13; endpoint types: /individuals/171/type; /individuals/173/type`
PGK1 Scer `SGD:S000000605`	enables	phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002333 gomodel:YCR012W-MONOMER_PHOSGLYPHOS-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/14; endpoint types: /individuals/33/type; /individuals/38/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	has_input	3-phosphonato-D-glyceroyl phosphate(4-) `CHEBI:57604`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002233 gomodel:CHEBI_57604_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/15; endpoint types: /individuals/33/type; /individuals/17/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	provides_input_for	6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002413 gomodel:6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/16; endpoint types: /individuals/29/type; /individuals/111/type`
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/17; endpoint types: /individuals/32/type; /individuals/112/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_input	NAD(1-) `CHEBI:57540`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002233 gomodel:CHEBI_57540_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/18; endpoint types: /individuals/30/type; /individuals/16/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/19; endpoint types: /individuals/143/type; /individuals/112/type`
CPX-554 Scer `SGD:S000218025`	enables	6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002333 gomodel:YeastPathways_GLYCOLYSIS/6690711d00000315. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/20; endpoint types: /individuals/111/type; /individuals/192/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/21; endpoint types: /individuals/35/type; /individuals/124/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/22; endpoint types: /individuals/111/type; /individuals/112/type`
PGI1 Scer `SGD:S000000400`	enables	glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN RO:0002333 gomodel:YBR196C-MONOMER_PGLUCISOM-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/23; endpoint types: /individuals/32/type; /individuals/37/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN BFO:0000066 gomodel:reaction_PHOSGLYPHOS-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/24; endpoint types: /individuals/33/type; /individuals/107/type`
PYK2 Scer `SGD:S000005874`	enables	pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002333 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004641. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/25; endpoint types: /individuals/171/type; /individuals/176/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 BFO:0000066 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004631. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/26; endpoint types: /individuals/162/type; /individuals/166/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	has_output	water `CHEBI:15377`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002234 gomodel:CHEBI_15377_2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/27; endpoint types: /individuals/110/type; /individuals/1/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	has_output	glycerone phosphate(2-) `CHEBI:57642`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002234 gomodel:CHEBI_57642_F16ALDOLASE-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/28; endpoint types: /individuals/28/type; /individuals/20/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	has_output	pyruvate `CHEBI:15361`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004639. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/29; endpoint types: /individuals/171/type; /individuals/174/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/30; endpoint types: /individuals/29/type; /individuals/112/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	has_output	water `CHEBI:15377`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004628. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/31; endpoint types: /individuals/162/type; /individuals/164/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_output	3-phosphonato-D-glyceroyl phosphate(4-) `CHEBI:57604`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002234 gomodel:CHEBI_57604_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/32; endpoint types: /individuals/124/type; /individuals/17/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN BFO:0000066 gomodel:reaction_PEPDEPHOS-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/33; endpoint types: /individuals/31/type; /individuals/105/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 BFO:0000066 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004643. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/34; endpoint types: /individuals/171/type; /individuals/177/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	has_input	beta-D-fructofuranose 1,6-bisphosphate(4-) `CHEBI:32966`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002233 gomodel:CHEBI_32966_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/35; endpoint types: /individuals/28/type; /individuals/9/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	has_input	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002233 gomodel:CHEBI_15378_PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/36; endpoint types: /individuals/31/type; /individuals/5/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	has_output	ATP(4-) `CHEBI:30616`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004640. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/37; endpoint types: /individuals/171/type; /individuals/175/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/38; endpoint types: /individuals/35/type; /individuals/112/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_input	NAD(1-) `CHEBI:57540`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004580. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/39; endpoint types: /individuals/124/type; /individuals/125/type`
FBA1 Scer `SGD:S000001543`	enables	fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002333 gomodel:YKL060C-MONOMER_F16ALDOLASE-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/40; endpoint types: /individuals/28/type; /individuals/42/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	has_output	D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002234 gomodel:CHEBI_59776_TRIOSEPISOMERIZATION-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/41; endpoint types: /individuals/35/type; /individuals/27/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	has_output	ATP(4-) `CHEBI:30616`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002234 gomodel:CHEBI_30616_PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/42; endpoint types: /individuals/33/type; /individuals/8/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	has_output	pyruvate `CHEBI:15361`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002234 gomodel:CHEBI_15361_PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/43; endpoint types: /individuals/31/type; /individuals/0/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	provides_input_for	pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/44; endpoint types: /individuals/162/type; /individuals/171/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	has_input	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004637. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/45; endpoint types: /individuals/171/type; /individuals/172/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/46; endpoint types: /individuals/124/type; /individuals/112/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN BFO:0000066 gomodel:reaction_F16ALDOLASE-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/47; endpoint types: /individuals/28/type; /individuals/102/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/48; endpoint types: /individuals/33/type; /individuals/112/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	has_output	beta-D-fructofuranose 1,6-bisphosphate(4-) `CHEBI:32966`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002234 gomodel:CHEBI_32966_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/49; endpoint types: /individuals/111/type; /individuals/9/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_output	NADH(2-) `CHEBI:57945`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002234 gomodel:CHEBI_57945_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/50; endpoint types: /individuals/30/type; /individuals/21/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	provides_input_for	fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002413 gomodel:F16ALDOLASE-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/51; endpoint types: /individuals/111/type; /individuals/28/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/52; endpoint types: /individuals/28/type; /individuals/124/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	has_input	water `CHEBI:15377`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002233 gomodel:CHEBI_15377_F16BDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/53; endpoint types: /individuals/29/type; /individuals/2/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	has_output	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002234 gomodel:CHEBI_15378_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/54; endpoint types: /individuals/111/type; /individuals/3/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	has_output	phosphonatoenolpyruvate `CHEBI:58702`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002234 gomodel:CHEBI_58702_2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/55; endpoint types: /individuals/162/type; /individuals/25/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN BFO:0000066 gomodel:reaction_GAPOXNPHOSPHN-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/56; endpoint types: /individuals/30/type; /individuals/104/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002413 gomodel:GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/57; endpoint types: /individuals/35/type; /individuals/30/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	provides_input_for	phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002413 gomodel:PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/58; endpoint types: /individuals/143/type; /individuals/33/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	has_input	2-phosphonato-D-glycerate(3-) `CHEBI:58289`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004627. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/59; endpoint types: /individuals/162/type; /individuals/163/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_input	D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002233 gomodel:CHEBI_59776_TRIOSEPISOMERIZATION-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/60; endpoint types: /individuals/143/type; /individuals/27/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_output	3-phosphonato-D-glyceroyl phosphate(4-) `CHEBI:57604`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002234 gomodel:CHEBI_57604_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/61; endpoint types: /individuals/30/type; /individuals/17/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN BFO:0000066 gomodel:reaction_6PFRUCTPHOS-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/62; endpoint types: /individuals/111/type; /individuals/101/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_input	hydrogenphosphate `CHEBI:43474`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002233 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004608. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/63; endpoint types: /individuals/143/type; /individuals/145/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_output	NADH(2-) `CHEBI:57945`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004583. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/64; endpoint types: /individuals/124/type; /individuals/128/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	has_output	hydrogenphosphate `CHEBI:43474`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002234 gomodel:CHEBI_43474_F16BDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/65; endpoint types: /individuals/29/type; /individuals/11/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_output	3-phosphonato-D-glyceroyl phosphate(4-) `CHEBI:57604`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002234 gomodel:CHEBI_57604_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/66; endpoint types: /individuals/143/type; /individuals/17/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	has_input	phosphonatoenolpyruvate `CHEBI:58702`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002233 gomodel:CHEBI_58702_2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/67; endpoint types: /individuals/31/type; /individuals/25/type`
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	has_input	D-glucopyranose 6-phosphate `CHEBI:4170`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN RO:0002233 gomodel:CHEBI_4170_PGLUCISOM-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/68; endpoint types: /individuals/32/type; /individuals/10/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/69; endpoint types: /individuals/162/type; /individuals/112/type`
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	provides_input_for	6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN RO:0002413 gomodel:6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/70; endpoint types: /individuals/32/type; /individuals/111/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	provides_input_for	phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 RO:0002413 gomodel:2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/71; endpoint types: /individuals/34/type; /individuals/110/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_output	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002234 gomodel:CHEBI_15378_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/72; endpoint types: /individuals/30/type; /individuals/4/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	has_output	D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002234 gomodel:CHEBI_59776_F16ALDOLASE-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/73; endpoint types: /individuals/28/type; /individuals/26/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_output	NADH(2-) `CHEBI:57945`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004610. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/74; endpoint types: /individuals/143/type; /individuals/147/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/75; endpoint types: /individuals/30/type; /individuals/112/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	has_output	ATP(4-) `CHEBI:30616`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002234 gomodel:CHEBI_30616_PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/76; endpoint types: /individuals/31/type; /individuals/7/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	provides_input_for	phosphoglycerate mutase activity `gomodel:RXN-15513`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002413 gomodel:RXN-15513. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/77; endpoint types: /individuals/33/type; /individuals/34/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	has_input	ATP(4-) `CHEBI:30616`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002233 gomodel:CHEBI_30616_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/78; endpoint types: /individuals/111/type; /individuals/6/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	has_output	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004609. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/79; endpoint types: /individuals/143/type; /individuals/146/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	has_input	2-phosphonato-D-glycerate(3-) `CHEBI:58289`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002233 gomodel:CHEBI_58289_3PGAREARR-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/80; endpoint types: /individuals/110/type; /individuals/23/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 BFO:0000066 gomodel:reaction_RXN-15513_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/81; endpoint types: /individuals/34/type; /individuals/108/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	provides_input_for	fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002413 gomodel:F16BDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/82; endpoint types: /individuals/111/type; /individuals/29/type`
ENO1 Scer `SGD:S000003486`	enables	phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002333 gomodel:YGR254W-MONOMER_2PGADEHYDRAT-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/83; endpoint types: /individuals/110/type; /individuals/40/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	has_output	2-phosphonato-D-glycerate(3-) `CHEBI:58289`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 RO:0002234 gomodel:CHEBI_58289_RXN-15513. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/84; endpoint types: /individuals/34/type; /individuals/24/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	has_input	ADP(3-) `CHEBI:456216`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002233 gomodel:CHEBI_456216_PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/85; endpoint types: /individuals/31/type; /individuals/14/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN BFO:0000066 gomodel:reaction_F16BDEPHOS-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/86; endpoint types: /individuals/29/type; /individuals/103/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	has_input	beta-D-fructofuranose 1,6-bisphosphate(4-) `CHEBI:32966`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002233 gomodel:CHEBI_32966_6PFRUCTPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/87; endpoint types: /individuals/29/type; /individuals/9/type`
6-phosphofructokinase activity `gomodel:6PFRUCTPHOS-RXN`	has_input	beta-D-fructofuranose 6-phosphate(2-) `CHEBI:57634`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:6PFRUCTPHOS-RXN RO:0002233 gomodel:CHEBI_57634_F16BDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/88; endpoint types: /individuals/111/type; /individuals/18/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	provides_input_for	pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002413 gomodel:PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/89; endpoint types: /individuals/110/type; /individuals/31/type`
TDH1 Scer `SGD:S000003588`	enables	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002333 gomodel:YJL052W-MONOMER_GAPOXNPHOSPHN-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/90; endpoint types: /individuals/30/type; /individuals/41/type`
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	has_output	beta-D-fructofuranose 6-phosphate(2-) `CHEBI:57634`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN RO:0002234 gomodel:CHEBI_57634_PGLUCISOM-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/91; endpoint types: /individuals/32/type; /individuals/19/type`
TDH2 Scer `SGD:S000003769`	enables	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002333 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004586. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/92; endpoint types: /individuals/124/type; /individuals/129/type`
glucose-6-phosphate isomerase activity `gomodel:PGLUCISOM-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PGLUCISOM-RXN BFO:0000066 gomodel:reaction_PGLUCISOM-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/93; endpoint types: /individuals/32/type; /individuals/106/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_input	D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002233 gomodel:CHEBI_59776_TRIOSEPISOMERIZATION-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/94; endpoint types: /individuals/124/type; /individuals/27/type`
TPI1 Scer `SGD:S000002457`	enables	triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002333 gomodel:YDR050C-MONOMER_TRIOSEPISOMERIZATION-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/95; endpoint types: /individuals/35/type; /individuals/39/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	has_input	3-phosphonato-D-glycerate(3-) `CHEBI:58272`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 RO:0002233 gomodel:CHEBI_58272_PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/96; endpoint types: /individuals/34/type; /individuals/22/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	provides_input_for	phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002413 gomodel:PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/97; endpoint types: /individuals/30/type; /individuals/33/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN RO:0002413 gomodel:GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/98; endpoint types: /individuals/28/type; /individuals/30/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	provides_input_for	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/99; endpoint types: /individuals/35/type; /individuals/143/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN BFO:0000066 gomodel:reaction_TRIOSEPISOMERIZATION-RXN_location_lociGO_0005829. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/100; endpoint types: /individuals/35/type; /individuals/109/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	has_output	hydron `CHEBI:15378`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002234 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004582. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/101; endpoint types: /individuals/124/type; /individuals/127/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_input	D-glyceraldehyde 3-phosphate(2-) `CHEBI:59776`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002233 gomodel:CHEBI_59776_TRIOSEPISOMERIZATION-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/102; endpoint types: /individuals/30/type; /individuals/27/type`
pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/103; endpoint types: /individuals/31/type; /individuals/112/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579`	provides_input_for	phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004579 RO:0002413 gomodel:PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/104; endpoint types: /individuals/124/type; /individuals/33/type`
TDH3 Scer `SGD:S000003424`	enables	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 RO:0002333 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004611. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/105; endpoint types: /individuals/143/type; /individuals/148/type`
phosphopyruvate hydratase activity `gomodel:2PGADEHYDRAT-RXN`	provides_input_for	pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:2PGADEHYDRAT-RXN RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/106; endpoint types: /individuals/110/type; /individuals/171/type`
triose-phosphate isomerase activity `gomodel:TRIOSEPISOMERIZATION-RXN`	has_input	glycerone phosphate(2-) `CHEBI:57642`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:TRIOSEPISOMERIZATION-RXN RO:0002233 gomodel:CHEBI_57642_F16ALDOLASE-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/107; endpoint types: /individuals/35/type; /individuals/20/type`
phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	provides_input_for	pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002413 gomodel:PEPDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/108; endpoint types: /individuals/162/type; /individuals/31/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606`	occurs_in	cytosol `GO:0005829`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004606 BFO:0000066 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004613. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/109; endpoint types: /individuals/143/type; /individuals/149/type`
phosphoglycerate mutase activity `gomodel:RXN-15513`	provides_input_for	phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:RXN-15513 RO:0002413 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/110; endpoint types: /individuals/34/type; /individuals/162/type`
fructose-bisphosphate aldolase activity `gomodel:F16ALDOLASE-RXN`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16ALDOLASE-RXN BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/111; endpoint types: /individuals/28/type; /individuals/112/type`
CDC19 Scer `SGD:S000000036`	enables	pyruvate kinase activity `gomodel:PEPDEPHOS-RXN`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PEPDEPHOS-RXN RO:0002333 gomodel:YAL038W-MONOMER_PEPDEPHOS-RXN_controller. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/112; endpoint types: /individuals/31/type; /individuals/36/type`
ENO2 Scer `SGD:S000001217`	enables	phosphopyruvate hydratase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004626 RO:0002333 gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004629. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/113; endpoint types: /individuals/162/type; /individuals/165/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	part_of	glycolytic process through glucose-6-phosphate `GO:0061620`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 BFO:0000050 gomodel:YeastPathways_GLYCOLYSIS/YeastPathways_GLYCOLYSIS. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/114; endpoint types: /individuals/171/type; /individuals/112/type`
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity `gomodel:GAPOXNPHOSPHN-RXN`	has_input	hydrogenphosphate `CHEBI:43474`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:GAPOXNPHOSPHN-RXN RO:0002233 gomodel:CHEBI_43474_GAPOXNPHOSPHN-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/115; endpoint types: /individuals/30/type; /individuals/12/type`
fructose 1,6-bisphosphate 1-phosphatase activity `gomodel:F16BDEPHOS-RXN`	has_output	beta-D-fructofuranose 6-phosphate(2-) `CHEBI:57634`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:F16BDEPHOS-RXN RO:0002234 gomodel:CHEBI_57634_F16BDEPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/116; endpoint types: /individuals/29/type; /individuals/18/type`
phosphoglycerate kinase activity `gomodel:PHOSGLYPHOS-RXN`	has_input	ADP(3-) `CHEBI:456216`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:PHOSGLYPHOS-RXN RO:0002233 gomodel:CHEBI_456216_PHOSGLYPHOS-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/117; endpoint types: /individuals/33/type; /individuals/15/type`
pyruvate kinase activity `gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636`	has_input	phosphonatoenolpyruvate `CHEBI:58702`	gomodel:YeastPathways_GLYCOLYSIS Source assertion: The model asserts gomodel:YeastPathways_GLYCOLYSIS/6a4c244800004636 RO:0002233 gomodel:CHEBI_58702_2PGADEHYDRAT-RXN. Source location `./YeastPathways_GLYCOLYSIS.json#/facts/118; endpoint types: /individuals/171/type; /individuals/25/type`
CPX-554 Scer `SGD:S000218025`	has_part ECO:0000353: physical interaction evidence; source stoichiometry minValue: 4, maxValue: 4	ATP-dependent 6-phosphofructokinase subunit alpha `UniProtKB:P16861`	SGD:S000218025 Source assertion: Complex Portal CPX-554 lists P16861 as a protein component; complex evidence is ECO:0000353: physical interaction evidence. Source location `Complex Portal JSON #/participants/0; /evidenceType`
CPX-554 Scer `SGD:S000218025`	has_part ECO:0000353: physical interaction evidence; source stoichiometry minValue: 4, maxValue: 4	ATP-dependent 6-phosphofructokinase subunit beta `UniProtKB:P16862`	SGD:S000218025 Source assertion: Complex Portal CPX-554 lists P16862 as a protein component; complex evidence is ECO:0000353: physical interaction evidence. Source location `Complex Portal JSON #/participants/1; /evidenceType`
GPM1 Scer `SGD:S000001635`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095)	cytoplasm `GO:0005737`	UniProtKB:P00950 Source assertion: UniProtKB:P00950 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00950 Source assertion: UniProtKB:P00950 has the exact SGD cross-reference SGD:S000001635. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
GPM1 Scer `SGD:S000001635`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:16823961); ECO:0000269 (PubMed:16962558) Topology: Peripheral membrane protein. Orientation: Cytoplasmic side.	mitochondrial outer membrane `GO:0005741`	UniProtKB:P00950 Source assertion: UniProtKB:P00950 annotates location Mitochondrion outer membrane (SL-0172). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/comments/1/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00950 Source assertion: UniProtKB:P00950 has the exact SGD cross-reference SGD:S000001635. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
GPM1 Scer `SGD:S000001635`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:22984289)	mitochondrial intermembrane space `GO:0005758`	UniProtKB:P00950 Source assertion: UniProtKB:P00950 annotates location Mitochondrion intermembrane space (SL-0169). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/comments/1/subcellularLocations/2; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00950 Source assertion: UniProtKB:P00950 has the exact SGD cross-reference SGD:S000001635. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/51/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
PGK1 Scer `SGD:S000000605`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:11502169)	cytoplasm `GO:0005737`	UniProtKB:P00560 Source assertion: UniProtKB:P00560 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/35/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00560 Source assertion: UniProtKB:P00560 has the exact SGD cross-reference SGD:S000000605. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/35/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
PGK1 Scer `SGD:S000000605`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:16823961)	mitochondrion `GO:0005739`	UniProtKB:P00560 Source assertion: UniProtKB:P00560 annotates location Mitochondrion (SL-0173). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/35/comments/1/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00560 Source assertion: UniProtKB:P00560 has the exact SGD cross-reference SGD:S000000605. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/35/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
PGI1 Scer `SGD:S000000400`	located_in Physical protein location from reviewed UniProt. ECO:0000250 (UniProtKB:P78917)	cytosol `GO:0005829`	UniProtKB:P12709 Source assertion: UniProtKB:P12709 annotates location Cytoplasm, cytosol (SL-0091). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/351/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P12709 Source assertion: UniProtKB:P12709 has the exact SGD cross-reference SGD:S000000400. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/351/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ENO1 Scer `SGD:S000003486`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:11502169)	cytoplasm `GO:0005737`	UniProtKB:P00924 Source assertion: UniProtKB:P00924 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/46/comments/0/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00924 Source assertion: UniProtKB:P00924 has the exact SGD cross-reference SGD:S000003486. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/46/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
TDH1 Scer `SGD:S000003588`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:11502169)	cytoplasm `GO:0005737`	UniProtKB:P00360 Source assertion: UniProtKB:P00360 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/26/comments/2/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00360 Source assertion: UniProtKB:P00360 has the exact SGD cross-reference SGD:S000003588. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/26/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
TDH2 Scer `SGD:S000003769`	located_in Physical protein location from reviewed UniProt. ECO:0000250 (UniProtKB:P00360)	cytoplasm `GO:0005737`	UniProtKB:P00358 Source assertion: UniProtKB:P00358 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/24/comments/2/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00358 Source assertion: UniProtKB:P00358 has the exact SGD cross-reference SGD:S000003769. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/24/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
TDH3 Scer `SGD:S000003424`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:11502169)	cytoplasm `GO:0005737`	UniProtKB:P00359 Source assertion: UniProtKB:P00359 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/25/comments/2/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00359 Source assertion: UniProtKB:P00359 has the exact SGD cross-reference SGD:S000003424. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/25/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
TDH3 Scer `SGD:S000003424`	located_in Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:16823961)	mitochondrion `GO:0005739`	UniProtKB:P00359 Source assertion: UniProtKB:P00359 annotates location Mitochondrion (SL-0173). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/25/comments/2/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00359 Source assertion: UniProtKB:P00359 has the exact SGD cross-reference SGD:S000003424. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/25/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ENO2 Scer `SGD:S000001217`	located_in Physical protein location from reviewed UniProt. evidence code not specified by source	cytoplasm `GO:0005737`	UniProtKB:P00925 Source assertion: UniProtKB:P00925 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/47/comments/0/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d` UniProtKB:P00925 Source assertion: UniProtKB:P00925 has the exact SGD cross-reference SGD:S000001217. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/47/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ATP-dependent 6-phosphofructokinase subunit alpha `UniProtKB:P16861`	located_in Physical protein location from reviewed UniProt. ECO:0000255 (HAMAP-Rule:MF_03184); ECO:0000269 (PubMed:18313953)	cytoplasm `GO:0005737`	UniProtKB:P16861 Source assertion: UniProtKB:P16861 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/450/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ATP-dependent 6-phosphofructokinase subunit alpha `UniProtKB:P16861`	located_in Physical protein location from reviewed UniProt. evidence code not specified by source Topology: Peripheral membrane protein. Orientation: Cytoplasmic side.	mitochondrial outer membrane `GO:0005741`	UniProtKB:P16861 Source assertion: UniProtKB:P16861 annotates location Mitochondrion outer membrane (SL-0172). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/450/comments/1/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ATP-dependent 6-phosphofructokinase subunit beta `UniProtKB:P16862`	located_in Physical protein location from reviewed UniProt. ECO:0000255 (HAMAP-Rule:MF_03184); ECO:0000269 (PubMed:18313953)	cytoplasm `GO:0005737`	UniProtKB:P16862 Source assertion: UniProtKB:P16862 annotates location Cytoplasm (SL-0086). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/451/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
ATP-dependent 6-phosphofructokinase subunit beta `UniProtKB:P16862`	located_in Physical protein location from reviewed UniProt. evidence code not specified by source Topology: Peripheral membrane protein. Orientation: Cytoplasmic side.	mitochondrial outer membrane `GO:0005741`	UniProtKB:P16862 Source assertion: UniProtKB:P16862 annotates location Mitochondrion outer membrane (SL-0172). Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/451/comments/1/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d`
FBP1 Scer `SGD:S000004369`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250 (UniProtKB:P00636) Binds 3 Mg(2+) ions per subunit. UniProt note evidence: ECO:0000250 (UniProtKB:P00636)	magnesium(2+) `CHEBI:18420`	UniProtKB:P09201 Source assertion: UniProtKB:P09201 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/222/comments/0/cofactors/0; /results/222/comments/0/note` UniProtKB:P09201 Source assertion: UniProtKB:P09201 has the exact SGD cross-reference SGD:S000004369. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/222/uniProtKBCrossReferences/0`
PGK1 Scer `SGD:S000000605`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250 (UniProtKB:P00558)	magnesium(2+) `CHEBI:18420`	UniProtKB:P00560 Source assertion: UniProtKB:P00560 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/35/comments/0/cofactors/0` UniProtKB:P00560 Source assertion: UniProtKB:P00560 has the exact SGD cross-reference SGD:S000000605. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/35/uniProtKBCrossReferences/0`
PYK2 Scer `SGD:S000005874`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250	magnesium(2+) `CHEBI:18420`	UniProtKB:P52489 Source assertion: UniProtKB:P52489 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2071/comments/0/cofactors/0` UniProtKB:P52489 Source assertion: UniProtKB:P52489 has the exact SGD cross-reference SGD:S000005874. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2071/uniProtKBCrossReferences/0`
PYK2 Scer `SGD:S000005874`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250	potassium(1+) `CHEBI:29103`	UniProtKB:P52489 Source assertion: UniProtKB:P52489 annotates CHEBI:29103 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2071/comments/1/cofactors/0` UniProtKB:P52489 Source assertion: UniProtKB:P52489 has the exact SGD cross-reference SGD:S000005874. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/2071/uniProtKBCrossReferences/0`
FBA1 Scer `SGD:S000001543`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250 Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. UniProt note evidence: ECO:0000250	zinc(2+) `CHEBI:29105`	UniProtKB:P14540 Source assertion: UniProtKB:P14540 annotates CHEBI:29105 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/387/comments/0/cofactors/0; /results/387/comments/0/note` UniProtKB:P14540 Source assertion: UniProtKB:P14540 has the exact SGD cross-reference SGD:S000001543. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/387/uniProtKBCrossReferences/0`
ENO1 Scer `SGD:S000003486`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000269 (PubMed:8605183) Mg(2+) is required for catalysis and for stabilizing the dimer. UniProt note evidence: ECO:0000269 (PubMed:8605183)	magnesium(2+) `CHEBI:18420`	UniProtKB:P00924 Source assertion: UniProtKB:P00924 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/46/comments/0/cofactors/0; /results/46/comments/0/note` UniProtKB:P00924 Source assertion: UniProtKB:P00924 has the exact SGD cross-reference SGD:S000003486. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/46/uniProtKBCrossReferences/0`
CDC19 Scer `SGD:S000000036`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000269 (PubMed:10413488)	magnesium(2+) `CHEBI:18420`	UniProtKB:P00549 Source assertion: UniProtKB:P00549 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/34/comments/0/cofactors/0` UniProtKB:P00549 Source assertion: UniProtKB:P00549 has the exact SGD cross-reference SGD:S000000036. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/34/uniProtKBCrossReferences/0`
CDC19 Scer `SGD:S000000036`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000305 (PubMed:9519410)	potassium(1+) `CHEBI:29103`	UniProtKB:P00549 Source assertion: UniProtKB:P00549 annotates CHEBI:29103 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/34/comments/1/cofactors/0` UniProtKB:P00549 Source assertion: UniProtKB:P00549 has the exact SGD cross-reference SGD:S000000036. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/34/uniProtKBCrossReferences/0`
ENO2 Scer `SGD:S000001217`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: not specified Mg(2+) is required for catalysis and for stabilizing the dimer.	magnesium(2+) `CHEBI:18420`	UniProtKB:P00925 Source assertion: UniProtKB:P00925 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/47/comments/0/cofactors/0; /results/47/comments/0/note` UniProtKB:P00925 Source assertion: UniProtKB:P00925 has the exact SGD cross-reference SGD:S000001217. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/47/uniProtKBCrossReferences/0`
ATP-dependent 6-phosphofructokinase subunit alpha `UniProtKB:P16861`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000250 (UniProtKB:P0A796); ECO:0000255 (HAMAP-Rule:MF_03184)	magnesium(2+) `CHEBI:18420`	UniProtKB:P16861 Source assertion: UniProtKB:P16861 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/450/comments/0/cofactors/0`
ATP-dependent 6-phosphofructokinase subunit beta `UniProtKB:P16862`	has_cofactor UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000255 (HAMAP-Rule:MF_03184)	magnesium(2+) `CHEBI:18420`	UniProtKB:P16862 Source assertion: UniProtKB:P16862 annotates CHEBI:18420 as a cofactor of this protein. Source location `https://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/451/comments/0/cofactors/0`

References

gomodel:YeastPathways_GLYCOLYSIS SGD GO-CAM glycolysis I (from glucose 6-phosphate) model (source version: Pinned Noctua JSON archive; model date 2026-07-30; member ./YeastPathways_GLYCOLYSIS.json)
SGD:S000218025 Complex Portal CPX-554: 6-phosphofructokinase complex (source version: Inspected API snapshot 2026-10-05; release dates 2014-10-16)
UniProtKB:P00950 Reviewed UniProtKB P00950 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00560 Reviewed UniProtKB P00560 location annotations (source version: UniProt release 2026_03)
UniProtKB:P12709 Reviewed UniProtKB P12709 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00924 Reviewed UniProtKB P00924 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00360 Reviewed UniProtKB P00360 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00358 Reviewed UniProtKB P00358 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00359 Reviewed UniProtKB P00359 location annotations (source version: UniProt release 2026_03)
UniProtKB:P00925 Reviewed UniProtKB P00925 location annotations (source version: UniProt release 2026_03)
UniProtKB:P16861 Reviewed UniProtKB P16861 location annotations (source version: UniProt release 2026_03)
UniProtKB:P16862 Reviewed UniProtKB P16862 location annotations (source version: UniProt release 2026_03)
UniProtKB:P09201 UniProtKB P09201 cofactor annotations (source version: 2026_03)
UniProtKB:P52489 UniProtKB P52489 cofactor annotations (source version: 2026_03)
UniProtKB:P14540 UniProtKB P14540 cofactor annotations (source version: 2026_03)
UniProtKB:P00549 UniProtKB P00549 cofactor annotations (source version: 2026_03)

Curation history

2026-10-05T06:05:08Z Codex; review-causal-graph; Reviewed every native GO-CAM fact; preserved precise input/output, causal, location, membership and complex-part relations with traceable structured source evidence. Kept distinct generic physical instances and recorded source-scope exclusions in the cohort review ledger. Reviewed exact Complex Portal composition, source evidence grades, and independent physical complex locations.
2026-10-05T06:17:04Z Codex; review-complex-composition; Reviewed exact Complex Portal composition, source evidence grades, and independent physical complex locations; reused existing proteins through reviewed UniProt SGD cross-references.
2026-10-05T06:43:56Z Codex
- EDIT — Audit causal activity compartments and preserve scoped protein location evidence
  Reviewed all 14 activity location assignments and 15 mapped physical proteins against reviewed S288C UniProt release2026_03 location/function/caution batch SHA256 95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d. Added 16 independently supported location edges and quarantined 0 generic cytosol source assertions. Mapped physical protein locations via exact SGD cross-references; retained source ECO grades, molecular form and conditional notes. Physical protein location alone never generates activity location. Explicitly inspected functional assertions support bounded activity projections. Every original activity location and exclusion is recorded in reports/causal_graph_review/gocam-location-review.json. No independent location annotation is treated as an evidence gap, not a negative result. Cytoplasm is not narrowed to cytosol. Microsome fractions are not projected as in-vivo organelles. Semantic validation passed all85 records;4 independent source-role acceptance tests passed.
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