phospholipid biosynthesis II (Kennedy pathway)

gomodel:YeastPathways_PWY3O-259

Phospholipid biosynthesis II (Kennedy pathway) in Saccharomyces cerevisiae S288C phosphorylates ethanolaminium to O-phosphonatoethanaminium, converts that intermediate and CTP to CDP-ethanolamine, and transfers phosphoethanolamine from CDP-ethanolamine to 1,2-diacyl-sn-glycerol to form phosphatidylethanolamine.

Pathway type
lipid biosynthesis
Organism scope

Read the source YAML

Pathway network

23 nodes · 28 asserted directed edges

Arrows show recorded subject → object relationships, not necessarily metabolic flow. Select a node for details or an arrow for evidence. Scroll, zoom or find a node to explore.

Pathway network: phospholipid biosynthesis II (Kennedy pathway) 23 nodes · 28 asserted directed edges. Every arrow links to its evidence table row; nodes link to their component details. Isolated declared components are retained. SGD:S000002554 — enables → gomodel:ETHANOLAMINE-KINASE-RXN; Evidence: gomodel:YeastPathways_PWY3O-259enables gomodel:2.7.7.14-RXN — part_of → GO:0046474; Evidence: gomodel:YeastPathways_PWY3O-259part of gomodel:ETHANOLAMINE-KINASE-RXN — has_output → CHEBI:15378; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:2.7.7.14-RXN — has_input → CHEBI:58190; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:ETHANOLAMINE-KINASE-RXN — has_input → CHEBI:30616; Evidence: gomodel:YeastPathways_PWY3O-259has input SGD:S000001165 — enables → gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN; Evidence: gomodel:YeastPathways_PWY3O-259enables gomodel:ETHANOLAMINE-KINASE-RXN — occurs_in → GO:0005829; Evidence: gomodel:YeastPathways_PWY3O-259occurs in gomodel:ETHANOLAMINE-KINASE-RXN — has_output → CHEBI:58190; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — has_input → CHEBI:17815; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:ETHANOLAMINE-KINASE-RXN — has_output → CHEBI:456216; Evidence: gomodel:YeastPathways_PWY3O-259has output SGD:S000003239 — enables → gomodel:2.7.7.14-RXN; Evidence: gomodel:YeastPathways_PWY3O-259enables gomodel:2.7.7.14-RXN — occurs_in → GO:0005829; Evidence: gomodel:YeastPathways_PWY3O-259occurs in gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — has_output → CHEBI:60377; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — has_output → CHEBI:15378; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:ETHANOLAMINE-KINASE-RXN — has_input → CHEBI:57603; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — has_output → CHEBI:16038; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — part_of → GO:0046474; Evidence: gomodel:YeastPathways_PWY3O-259part of gomodel:2.7.7.14-RXN — has_input → CHEBI:15378; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:2.7.7.14-RXN — has_output → CHEBI:29888; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:2.7.7.14-RXN — has_output → CHEBI:57876; Evidence: gomodel:YeastPathways_PWY3O-259has output gomodel:2.7.7.14-RXN — has_input → CHEBI:37563; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN — has_input → CHEBI:57876; Evidence: gomodel:YeastPathways_PWY3O-259has input gomodel:ETHANOLAMINE-KINASE-RXN — part_of → GO:0046474; Evidence: gomodel:YeastPathways_PWY3O-259part of SGD:S000002554 — located_in → GO:0005737; Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095); Evidence: UniProtKB:Q03764, UniProtKB:Q03764located in SGD:S000001165 — located_in → GO:0000139; Physical protein location from reviewed UniProt. evidence code not specified by source Topology: Multi-pass membrane protein.; Evidence: UniProtKB:P22140, UniProtKB:P22140located in SGD:S000003239 — located_in → GO:0005737; Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095); Evidence: UniProtKB:P33412, UniProtKB:P33412located in SGD:S000003239 — located_in → GO:0005634; Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095); Evidence: UniProtKB:P33412, UniProtKB:P33412located in SGD:S000001165 — has_cofactor → CHEBI:18420; UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000269 (PubMed:1847919); Evidence: UniProtKB:P22140, UniProtKB:P22140has cofactor EKI1 Scer; SGD:S000002554; Declared type: protein protein EKI1 Scer glycerophospholipid biosynthetic process; GO:0046474; Declared type: biological_process biological process glycerophospholipid biosynthetic process hydron; CHEBI:15378; Declared type: small_molecule small molecule hydron O-phosphonatoethanaminium(1-); CHEBI:58190; Declared type: small_molecule small molecule O-phosphonatoethanaminium(1- ) ATP(4-); CHEBI:30616; Declared type: small_molecule small molecule ATP(4-) cytosol; GO:0005829; Declared type: cellular_component cellular component cytosol EPT1 Scer; SGD:S000001165; Declared type: protein protein EPT1 Scer 1,2-diacyl-sn-glycerol; CHEBI:17815; Declared type: lipid lipid 1,2-diacyl-sn-glycerol ADP(3-); CHEBI:456216; Declared type: small_molecule small molecule ADP(3-) ECT1 Scer; SGD:S000003239; Declared type: protein protein ECT1 Scer cytidine 5'-monophosphate(2-); CHEBI:60377; Declared type: small_molecule small molecule cytidine 5'-monophosphate(2-) ethanolaminium(1+); CHEBI:57603; Declared type: small_molecule small molecule ethanolaminium(1+) phosphatidylethanolamine; CHEBI:16038; Declared type: lipid lipid phosphatidylethanolamine diphosphoric acid; CHEBI:29888; Declared type: small_molecule small molecule diphosphoric acid CDP-ethanolamine(1-); CHEBI:57876; Declared type: small_molecule small molecule CDP-ethanolamine(1-) CTP(4-); CHEBI:37563; Declared type: small_molecule small molecule CTP(4-) cytoplasm; GO:0005737; Declared type: cellular_component cellular component cytoplasm Golgi membrane; GO:0000139; Declared type: cellular_component cellular component Golgi membrane nucleus; GO:0005634; Declared type: cellular_component cellular component nucleus magnesium(2+); CHEBI:18420; Declared type: cofactor cofactor magnesium(2+) ethanolamine-phosphate cytidylyltransferase activity; gomodel:2.7.7.14-RXN; Declared type: molecular_activity molecular activity ethanolamine-phosphate cytidylyltransferase activity ethanolamine kinase activity; gomodel:ETHANOLAMINE-KINASE-RXN; Declared type: molecular_activity molecular activity ethanolamine kinase activity ethanolaminephosphotransferase activity; gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN; Declared type: molecular_activity molecular activity ethanolaminephosphotransfera se activity

Components and activities

Declared biological components and source reaction directions
NodeKind or roleSource direction
Saccharomyces cerevisiae S288C
NCBITaxon:559292		taxon
EKI1 Scer
SGD:S000002554		protein
glycerophospholipid biosynthetic process
GO:0046474		biological process
hydron
CHEBI:15378		small molecule
O-phosphonatoethanaminium(1-)
CHEBI:58190		small molecule
ATP(4-)
CHEBI:30616		small molecule
cytosol
GO:0005829		cellular component
EPT1 Scer
SGD:S000001165		protein
1,2-diacyl-sn-glycerol
CHEBI:17815		lipid
ADP(3-)
CHEBI:456216		small molecule
ECT1 Scer
SGD:S000003239		protein
cytidine 5'-monophosphate(2-)
CHEBI:60377		small molecule
ethanolaminium(1+)
CHEBI:57603		small molecule
phosphatidylethanolamine
CHEBI:16038		lipid
diphosphoric acid
CHEBI:29888		small molecule
CDP-ethanolamine(1-)
CHEBI:57876		small molecule
CTP(4-)
CHEBI:37563		small molecule
cytoplasm
GO:0005737		cellular component
Golgi membrane
GO:0000139		cellular component
nucleus
GO:0005634		cellular component
magnesium(2+)
CHEBI:18420		cofactor
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		molecular activity
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		molecular activity
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		molecular activity

Mechanistic edges

Mechanistic edges and their cited evidence
SubjectPredicate and descriptionObjectEvidence
EKI1 Scer
SGD:S000002554		enables

ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002333 gomodel:YDR147W-MONOMER_ETHANOLAMINE-KINASE-RXN_controller.

    Source location./YeastPathways_PWY3O-259.json#/facts/0; endpoint types: /individuals/13/type; /individuals/15/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		part_of

glycerophospholipid biosynthetic process
GO:0046474
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN BFO:0000050 gomodel:YeastPathways_PWY3O-259/YeastPathways_PWY3O-259.

    Source location./YeastPathways_PWY3O-259.json#/facts/1; endpoint types: /individuals/42/type; /individuals/43/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		has_output

hydron
CHEBI:15378
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002234 gomodel:CHEBI_15378_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/2; endpoint types: /individuals/13/type; /individuals/1/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		has_input

O-phosphonatoethanaminium(1-)
CHEBI:58190
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002233 gomodel:CHEBI_58190_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/3; endpoint types: /individuals/42/type; /individuals/11/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		has_input

ATP(4-)
CHEBI:30616
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002233 gomodel:CHEBI_30616_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/4; endpoint types: /individuals/13/type; /individuals/6/type
EPT1 Scer
SGD:S000001165		enables

ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002333 gomodel:YHR123W-MONOMER_ETHANOLAMINEPHOSPHOTRANSFERASE-RXN_controller.

    Source location./YeastPathways_PWY3O-259.json#/facts/6; endpoint types: /individuals/14/type; /individuals/17/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		occurs_in

cytosol
GO:0005829
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN BFO:0000066 gomodel:reaction_ETHANOLAMINE-KINASE-RXN_location_lociGO_0005829.

    Source location./YeastPathways_PWY3O-259.json#/facts/7; endpoint types: /individuals/13/type; /individuals/40/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		has_output

O-phosphonatoethanaminium(1-)
CHEBI:58190
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002234 gomodel:CHEBI_58190_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/8; endpoint types: /individuals/13/type; /individuals/11/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		has_input

1,2-diacyl-sn-glycerol
CHEBI:17815
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002233 gomodel:CHEBI_17815_ETHANOLAMINEPHOSPHOTRANSFERASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/9; endpoint types: /individuals/14/type; /individuals/4/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		has_output

ADP(3-)
CHEBI:456216
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002234 gomodel:CHEBI_456216_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/10; endpoint types: /individuals/13/type; /individuals/8/type
ECT1 Scer
SGD:S000003239		enables

ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002333 gomodel:YGR007W-MONOMER_2.7.7.14-RXN_controller.

    Source location./YeastPathways_PWY3O-259.json#/facts/11; endpoint types: /individuals/42/type; /individuals/16/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		occurs_in

cytosol
GO:0005829
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN BFO:0000066 gomodel:reaction_2.7.7.14-RXN_location_lociGO_0005829.

    Source location./YeastPathways_PWY3O-259.json#/facts/12; endpoint types: /individuals/42/type; /individuals/39/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		has_output

cytidine 5'-monophosphate(2-)
CHEBI:60377
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002234 gomodel:CHEBI_60377_ETHANOLAMINEPHOSPHOTRANSFERASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/13; endpoint types: /individuals/14/type; /individuals/12/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		has_output

hydron
CHEBI:15378
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002234 gomodel:CHEBI_15378_ETHANOLAMINEPHOSPHOTRANSFERASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/14; endpoint types: /individuals/14/type; /individuals/2/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		has_input

ethanolaminium(1+)
CHEBI:57603
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN RO:0002233 gomodel:CHEBI_57603_ETHANOLAMINE-KINASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/15; endpoint types: /individuals/13/type; /individuals/9/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		has_output

phosphatidylethanolamine
CHEBI:16038
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002234 gomodel:CHEBI_16038_ETHANOLAMINEPHOSPHOTRANSFERASE-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/16; endpoint types: /individuals/14/type; /individuals/3/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		part_of

glycerophospholipid biosynthetic process
GO:0046474
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN BFO:0000050 gomodel:YeastPathways_PWY3O-259/YeastPathways_PWY3O-259.

    Source location./YeastPathways_PWY3O-259.json#/facts/17; endpoint types: /individuals/14/type; /individuals/43/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		has_input

hydron
CHEBI:15378
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002233 gomodel:CHEBI_15378_2.7.7.14-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/18; endpoint types: /individuals/42/type; /individuals/0/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		has_output

diphosphoric acid
CHEBI:29888
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002234 gomodel:CHEBI_29888_2.7.7.14-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/19; endpoint types: /individuals/42/type; /individuals/5/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		has_output

CDP-ethanolamine(1-)
CHEBI:57876
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002234 gomodel:CHEBI_57876_2.7.7.14-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/20; endpoint types: /individuals/42/type; /individuals/10/type
ethanolamine-phosphate cytidylyltransferase activity
gomodel:2.7.7.14-RXN		has_input

CTP(4-)
CHEBI:37563
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:2.7.7.14-RXN RO:0002233 gomodel:CHEBI_37563_2.7.7.14-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/21; endpoint types: /individuals/42/type; /individuals/7/type
ethanolaminephosphotransferase activity
gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN		has_input

CDP-ethanolamine(1-)
CHEBI:57876
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN RO:0002233 gomodel:CHEBI_57876_2.7.7.14-RXN.

    Source location./YeastPathways_PWY3O-259.json#/facts/22; endpoint types: /individuals/14/type; /individuals/10/type
ethanolamine kinase activity
gomodel:ETHANOLAMINE-KINASE-RXN		part_of

glycerophospholipid biosynthetic process
GO:0046474
  • gomodel:YeastPathways_PWY3O-259

    Source assertion: The model asserts gomodel:ETHANOLAMINE-KINASE-RXN BFO:0000050 gomodel:YeastPathways_PWY3O-259/YeastPathways_PWY3O-259.

    Source location./YeastPathways_PWY3O-259.json#/facts/23; endpoint types: /individuals/13/type; /individuals/43/type
EKI1 Scer
SGD:S000002554		located_in

Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095)

cytoplasm
GO:0005737
  • UniProtKB:Q03764

    Source assertion: UniProtKB:Q03764 annotates location Cytoplasm (SL-0086).

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/4094/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
  • UniProtKB:Q03764

    Source assertion: UniProtKB:Q03764 has the exact SGD cross-reference SGD:S000002554.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/4094/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
EPT1 Scer
SGD:S000001165		located_in

Physical protein location from reviewed UniProt. evidence code not specified by source Topology: Multi-pass membrane protein.

Golgi membrane
GO:0000139
  • UniProtKB:P22140

    Source assertion: UniProtKB:P22140 annotates location Golgi apparatus membrane (SL-0134).

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/575/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
  • UniProtKB:P22140

    Source assertion: UniProtKB:P22140 has the exact SGD cross-reference SGD:S000001165.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/575/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
ECT1 Scer
SGD:S000003239		located_in

Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095)

cytoplasm
GO:0005737
  • UniProtKB:P33412

    Source assertion: UniProtKB:P33412 annotates location Cytoplasm (SL-0086).

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/3468/comments/1/subcellularLocations/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
  • UniProtKB:P33412

    Source assertion: UniProtKB:P33412 has the exact SGD cross-reference SGD:S000003239.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/3468/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
ECT1 Scer
SGD:S000003239		located_in

Physical protein location from reviewed UniProt. ECO:0000269 (PubMed:14562095)

nucleus
GO:0005634
  • UniProtKB:P33412

    Source assertion: UniProtKB:P33412 annotates location Nucleus (SL-0191).

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/3468/comments/1/subcellularLocations/1; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
  • UniProtKB:P33412

    Source assertion: UniProtKB:P33412 has the exact SGD cross-reference SGD:S000003239.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_subcellular_location%2Ccc_function%2Ccc_caution%2Corganism_id#/results/3468/uniProtKBCrossReferences/0; sha256=95f72dcc644358c480e0e59f996cf88533558b5fa4256460a030e0a1eaf9678d
EPT1 Scer
SGD:S000001165		has_cofactor

UniProtKB reviewed (Swiss-Prot) annotation. UniProt evidence: ECO:0000269 (PubMed:1847919)

magnesium(2+)
CHEBI:18420
  • UniProtKB:P22140

    Source assertion: UniProtKB:P22140 annotates CHEBI:18420 as a cofactor of this protein.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/575/comments/0/cofactors/0
  • UniProtKB:P22140

    Source assertion: UniProtKB:P22140 has the exact SGD cross-reference SGD:S000001165.

    Source locationhttps://rest.uniprot.org/uniprotkb/stream?query=taxonomy_id%3A559292+AND+reviewed%3Atrue&format=json&fields=accession%2Cprotein_name%2Cxref_sgd%2Ccc_cofactor%2Corganism_id%2Ccc_caution [sha256:1378282d22c5518215707964664b55946f468ba74a227a6ea1bbf27db69ddbc4] #/results/575/uniProtKBCrossReferences/0

References

Curation history