biosafety level 5

METPO:1001106 · CLASS · REVIEWED

A biosafety level that is proposed as a classification beyond BSL-4 for hypothetical biological agents requiring enhanced containment.

BSL-5 proposed enhanced-hazard classification

DOI-backed graph linking hypothetical pathogen hazards exceeding BSL-4 thresholds to the proposed BSL-5 enhanced-containment classification.

BSL-5 proposed enhanced-hazard classification Interactive directed graph showing evidence-backed causal relationships for biosafety level 5.

Edge evidence

  • enhanced pathogen hazard motivates biosafety level 5

    Hazards exceeding BSL-4 thresholds motivate the proposed BSL-5 enhanced-containment classification.

    • DOI:10.1146/annurev.micro.62.081307.162938 virulence factors Supports increasingly severe virulence-factor combinations as the rationale for hazard classes above BSL-4.
  • biosafety level 5 is a biosafety level rdfs:subClassOf

    BSL-5 is a proposed member of the biosafety-level classification.

    • DOI:10.1146/annurev.micro.62.081307.162938 virulence factors Supports BSL-5 as a proposed extension of the biosafety-level classification axis.

Provenance

Source
METPO (2025-11-25)
Definition source
DOI:10.1146/annurev.micro.62.081307.162938

Parent traits (1)

Synonyms (1)

  • 5 RELATED_SYNONYM · metpo.owl

kg-microbe context

Matched 1 kg-microbe node via direct_metpo.

  • METPO:1001106 [-1.943, -2.943, -2.758, +0.700, …]

512-dim DeepWalkSkipGramEnsmallen embedding from kg-microbe (2026-04-25).

Nearest neighbors in embedding space

Top-8 cosine-similar METPO traits from the 2026-04-25 deepwalk (512-D).

Curation history

  1. · SEEDED_FROM_METPO · seed_from_metpo

    imported from data/raw/metpo.owl (CLASS)

  2. · CURATED_CAUSAL_GRAPH · claude

    Added DOI-backed causal graph linking enhanced pathogen hazards to the proposed BSL-5 enhanced-containment classification.

  3. · GROUND_CAUSAL_PREDICATES · claude

    Grounded 1 causal-edge predicate_id field(s) via mappings/predicate_grounding.tsv (rdfs:subClassOf×1).