3'-deoxy-3',4'-didehydro-CTP

CHEBI:156336 ·resolve ·ANTIVIRAL ·EXACT SEEDED

An organic triphosphate resulting from the formal condensation of the 5'-hydroxy group of 3'-deoxy-3',4'-didehydro-cytidine with triphosphoric acid. It is a chain terminator for RNA-dependent RNA polymerases. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:38337 CHEBI:38337
CHEBI:62894 CHEBI:62894

Chemical structure

Computed structure properties
Molecular formula	C9H14N3O13P3
Charge	0
Average mass	465.141 Da
Monoisotopic mass	464.97395 Da
Source	ChEBI
InChIKey	DGUQXKKDZHTKIE-HTRCEHHLSA-N

SMILES

Nc1ccn([C@@H]2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)=C[C@H]2O)c(=O)n1

InChI

InChI=1S/C9H14N3O13P3/c10-7-1-2-12(9(14)11-7)8-6(13)3-5(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-3,6,8,13H,4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t6-,8-/m1/s1

Also called

({[({[(4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-4,5-dihydrofuran-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid (EXACT_SYNONYM)— chebi
3'-deoxy-3',4'-didehydro-cytidine triphosphate (EXACT_SYNONYM)— chebi
3'-deoxy-3',4'-didehydro-cytidine-5'-triphosphate (EXACT_SYNONYM)— chebi
[[(2R,3R)-2-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-2,3-dihydrofuran-5-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate (EXACT_SYNONYM)— chebi
ddh-CTP (EXACT_SYNONYM)— chebi
ddhC-triphosphate (EXACT_SYNONYM)— chebi
ddhCTP (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

chemspider:107448068

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:22587 CHEBI:22587

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:156336`	3'-deoxy-3',4'-didehydro-CTP	`antibioticmech:chebi-45db2cb2e4`	2026-08-30

Mechanism summary

Mode of action: VIRAL_POLYMERASE_INHIBITION microbial target — Assigned from ChEBI role CHEBI:170010 (EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.