Microbial pathway knowledge base

PathwayMech

Explore microbial pathways, their molecular participants, and the evidence behind their mechanistic connections.

Pathway records
271
Taxa represented
105
Mechanistic edges
14,384
Distinct references
5,875

Explore PathwayMech

Find a pathway, explore embedding spaces, follow its evidence, or contribute a record.

Pathway browser

Filter and search the published collection by pathway class, organism, protein grounding, or identifier.

Browse pathway records

Corpus text embedding map

Interactive 2D PaCMAP projection of BAAI/bge-large-en-v1.5 embeddings across all 271 pathway records.

Explore text embedding map

Sequence map (ESM-2 pLM)

Explore protein language model (ESM-2 650M) representations for UniProt-grounded pathway proteins and centroids.

Explore pLM sequence map

Source records & curation

Inspect the underlying YAML records and learn how to attach mechanistic evidence to individual pathway edges.

Explore source records

Downloads, schema & complete pathway graph

KGX TSV exports from the same 271 pathway records shown here: All nodes (TSV), All edges (TSV), Pathway index (JSON), and Version, row counts and file checksums.

LinkML Schema & Data Model: PathwayMech LinkML schema (pathwaymech.yaml) · Shared X-Mech primitives (mech_shared.yaml) · Curation history schema (history.yaml) · Source authority registry (sources.yaml) · Corpus text embedding coordinates (JSON) · ESM-2 sequence embedding coordinates (JSON).

Graph version: a0d9bb5b1e40ea4babe853d98af17593b1a68d26d3c7d3f09757bd92236983e9. Data: CC BY 4.0; upstream source terms still apply.