central plaque of mitotic spindle pole body

GO:0061493 · Cytoskeleton · Multiprotein complex · Proposed

One of three laminate structures that form the mitotic spindle pole body; the central plaque is embedded in the nuclear envelope. [DOI:10.1146/annurev.cellbio.20.022003.114106]

Part of: mitotic spindle pole body (GO:0044732)

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast is a characterized fungal model for the nuclear-envelope-embedded central plaque of the mitotic spindle pole body. [DOI:10.1146/annurev.cellbio.20.022003.114106]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast reference system in which the layered mitotic SPB and its central core architecture have been reviewed. [DOI:10.1146/annurev.cellbio.20.022003.114106]

The mitotic central plaque is a mitosis-specific SPB central plaque embedded in the budding-yeast nuclear envelope.

Subject	Predicate	Object	Evidence
central plaque of mitotic spindle pole body	is a	central plaque of spindle pole body	`GO:0061493` GO:0061493 is_a GO:0005823 in the Gene Ontology cellular-component hierarchy.
central plaque of mitotic spindle pole body	is part of	mitotic spindle pole body	`GO:0061493` GO:0061493 identifies a central-plaque substructure of the mitotic spindle pole body.
central plaque of mitotic spindle pole body	is embedded in	nuclear envelope	`DOI:10.1146/annurev.cellbio.20.022003.114106` Jaspersen and Winey 2004 reviewed the budding-yeast SPB central plaque as the nuclear-envelope-embedded SPB core. `DOI:10.1091/mbc.E17-06-0397` Viswanath et al. 2017 modeled the central plaque as the core of the budding-yeast SPB.

INTERPRETATION (RESOLVED): Keep the mitotic SPB central plaque narrower than the general SPB central plaque and avoid the malformed GO:0061493 definition text. GO:0061493 denotes the central plaque of the mitotic spindle pole body, is narrower than GO:0005823, and is part of the GO:0044732 mitotic spindle pole body. Its current definition text describes the inner plaque instead of the central plaque, so the local definition follows the existing GO:0005823 central-plaque boundary and SPB literature.
CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for mitotic central-plaque and SPB-core constituents. This first GO-backed mitotic central-plaque record captures the cell-cycle-specific layer without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for budding-yeast central-plaque and SPB-core proteins.

GO:0061493 Gene Ontology cellular-component term for the central plaque of the mitotic spindle pole body.
GO:0005823 Gene Ontology parent term for the general central plaque of the spindle pole body.
GO:0044732 Gene Ontology cellular-component term for the mitotic spindle pole body that includes GO:0061493 by parthood.
GO:0061497 Gene Ontology cellular-component sibling term for the inner plaque of the mitotic spindle pole body.
GO:0061499 Gene Ontology cellular-component sibling term for the outer plaque of the mitotic spindle pole body.
GO:0005635 Gene Ontology cellular-component term for the nuclear envelope in which the SPB central plaque is embedded.
DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.
DOI:10.1091/mbc.E17-06-0397 Viswanath et al. 2017, The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling, Molecular Biology of the Cell.

2026-09-29T16:16:06Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T16:17:17Z codex · EXPANDED_RECORD — Added GO-backed central-plaque parentage and mitotic-SPB parthood, Saccharomyces scope, GO and literature evidence, a nonmechanistic mitotic central-plaque topology graph, and boundary/component discussions.
2026-09-29T16:41:52Z codex · ADDRESSED_REVIEW — Resolved PR #1789 review issue #1790 by citing GO:0061497 and GO:0061499 as exact mitotic sibling plaque terms in the GO:0061493 record evidence and boundary discussion.