central plaque of spindle pole body

GO:0005823 · Cytoskeleton · Multiprotein complex · Proposed

One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope. [GO:0005823]

Part of: spindle pole body (GO:0005816)

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast is a characterized fungal model for the nuclear-envelope-embedded central plaque of the spindle pole body. [DOI:10.1146/annurev.cellbio.20.022003.114106]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast reference system in which the layered SPB and its central core architecture have been characterized. [DOI:10.1146/annurev.cellbio.20.022003.114106]

The central plaque is the nuclear-envelope-embedded laminate of the budding-yeast spindle pole body.

Subject	Predicate	Object	Evidence
central plaque of spindle pole body	is part of	spindle pole body	`GO:0005823` GO:0005823 defines the central plaque as one of the laminate structures that form the spindle pole body.
central plaque of spindle pole body	is embedded in	nuclear envelope	`GO:0005823` GO:0005823 defines the SPB central plaque as embedded in the nuclear envelope.

INTERPRETATION (RESOLVED): Keep the central plaque distinct from the inner and outer spindle-pole-body plaques. GO:0005823 denotes the nuclear-envelope-embedded laminate of the spindle pole body, while the adjacent inner and outer plaques are separately named SPB laminates with different cytoplasmic or nuclear topology.
CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for central-plaque and SPB-core constituents. The first GO-backed central-plaque record captures the lamina as a named SPB substructure without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for budding-yeast central-plaque or SPB-core constituents.

GO:0005823 Gene Ontology cellular-component term for the central plaque of the spindle pole body.
GO:0005816 Gene Ontology cellular-component term for the spindle pole body that includes the central plaque.
GO:0005635 Gene Ontology cellular-component term for the nuclear envelope where the central plaque is embedded.
GO:0005822 Gene Ontology cellular-component term for the inner plaque of the spindle pole body, the nuclear-facing sibling plaque.
GO:0005824 Gene Ontology cellular-component term for the outer plaque of the spindle pole body, the cytoplasmic sibling plaque.
DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.
DOI:10.1091/mbc.E17-06-0397 Viswanath et al. 2017, The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling, Molecular Biology of the Cell.

2026-09-29T07:36:59Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T07:38:12Z codex · EXPANDED_RECORD — Added spindle-pole-body parthood, Saccharomyces scope, GO and literature evidence, a nonmechanistic topology graph, and plaque component-boundary discussions.
2026-09-29T07:52:20Z codex · ADDRESSED_REVIEW — Resolved PR #1770 review issues #1771 and #1772 by citing the inner and outer plaque GO terms in the boundary discussion and narrowing the component TODO to central-plaque and SPB-core constituents.