cleavage apparatus septin structure

GO:0032161 · Cytoskeleton · Filament · Proposed

Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis. [GO:0032161]

Part of: cell cortex (GO:0005938); GO:0032153 — cell division site (no local record); GO:0032156 — septin cytoskeleton (no local record)

UniProt location names: UniProt Consortium, CC BY 4.0. Reference label and route sources.

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
septin proteins	Protein	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Septin GTPases that assemble into cytokinetic structures at the cleavage plane. `GO:0032161` GO:0032161 defines cleavage-apparatus septin structures as composed of septins and septin-associated proteins at the cleavage plane.

Mechanism graphs

Cleavage-plane septin-structure topology (ASSEMBLY)

Septin proteins assemble into septin-containing cytokinetic structures localized to the cell-division cleavage plane.

Subject	Predicate	Object	Evidence
septin proteins	assemble into	cleavage apparatus septin structure	`GO:0032161` GO:0032161 defines these cleavage-plane structures as composed of septins and septin-associated proteins.
cleavage apparatus septin structure	localizes to	cleavage plane	`GO:0032161` GO:0032161 localizes the generic septin structure class to the cleavage plane.
cleavage apparatus septin structure	is part of	cell division site	`GO:0032153` — cell division site OLS reports GO:0032161 as part_of GO:0032153.
cleavage apparatus septin structure	is part of	septin cytoskeleton	`GO:0032156` — septin cytoskeleton OLS reports GO:0032161 as part_of GO:0032156.

Discussions

INTERPRETATION (RESOLVED): Keep the generic cleavage apparatus septin structure distinct from localized bud-neck, prospore, and medial-cortex septin structures. GO:0032161 denotes the generic class of septin- and septin-associated-protein structures at cytokinetic cleavage planes. OLS lists GO:0000144, GO:0032174, GO:0032177, GO:0032169, and GO:0036391 as direct child terms for localized cleavage-plane septin structures.
CURATION_TODO (OPEN): Resolve the exact boundary and source-neutral groundings for cleavage-apparatus septins and septin-associated proteins. GO:0032161 includes septin-associated proteins as well as septins, but this first generic record keeps only the reviewed-label-only septin protein cohort rather than guessing which associated proteins are genuine constituents across all cleavage-plane child structures.

Evidence

GO:0032161 Gene Ontology cellular-component term for the cleavage apparatus septin structure.
GO:0110165 OLS reports GO:0110165 cellular anatomical structure as the direct GO:0032161 parent.
GO:0005938 OLS reports a direct GO:0032161 part_of relation to the cell cortex.
GO:0032153 — cell division site OLS reports a direct GO:0032161 part_of relation to the cell division site.
GO:0032156 — septin cytoskeleton OLS reports a direct GO:0032161 part_of relation to the septin cytoskeleton.
GO:0000144 OLS reports the cellular bud neck septin ring as a direct GO:0032161 child term.
GO:0032174 OLS reports the cellular bud neck septin collar as a direct GO:0032161 child term.
GO:0032177 OLS reports the cellular bud neck split septin rings as a direct GO:0032161 child term.
GO:0032169 OLS reports the prospore septin ring as a direct GO:0032161 child term.
GO:0036391 OLS reports the medial cortex septin ring as a direct GO:0032161 child term.

Curation history

2026-09-30T13:37:00Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-30T13:37:55Z codex · EXPANDED_RECORD — Added cellular-anatomical-structure parentage, cell-cortex, cell-division-site, and septin-cytoskeleton parthood, a reviewed-label-only septin constituent, GO-backed cleavage-plane topology, and boundary and component-grounding discussions.
2026-09-30T13:52:51Z codex · ADDRESSED_REVIEW — Resolved #1828 from PR #1827 by typing the GO:0032156 septin cytoskeleton graph node as STRUCTURE instead of CELLULAR_LOCALIZATION.

Source: data/structures/cytoskeleton/cleavage_apparatus_septin_structure.yaml