half bridge of mitotic spindle pole body
Structure adjacent to the plaques of the mitotic spindle pole body. [GO:0061496]
Part of: mitotic spindle pole body (GO:0044732)
Taxonomic distribution
NCBITaxon:4932Saccharomyces cerevisiae — COMMON: Budding yeast is a characterized fungal model in which mitotic SPB duplication begins at the half-bridge next to the existing spindle pole body. [DOI:10.1146/annurev.cellbio.20.022003.114106]
Canonical examples
NCBITaxon:4932Saccharomyces cerevisiae — Budding-yeast reference system in which half-bridge-linked SPB duplication has been characterized through the mitotic cell cycle. [DOI:10.1146/annurev.cellbio.20.022003.114106]
Functions
- mitotic spindle pole body duplication site — The mitotic half-bridge next to an existing budding-yeast SPB provides the site where daughter SPB assembly begins.
DOI:10.1146/annurev.cellbio.20.022003.114106Jaspersen and Winey 2004 reviewed budding-yeast SPB duplication during mitotic cell-cycle entry as a half-bridge-associated pathway.
Mechanism graphs
Mitotic half-bridge site for daughter spindle pole body assembly (ASSEMBLY)
The mitotic half bridge is a specialized spindle-pole-body half bridge that marks where a daughter SPB begins to assemble in budding yeast.
| Subject | Predicate | Object | Evidence |
|---|---|---|---|
| half bridge of mitotic spindle pole body | is a | half bridge of spindle pole body |
|
| half bridge of mitotic spindle pole body | is part of | mitotic spindle pole body |
|
| half bridge of mitotic spindle pole body | templates assembly of | daughter spindle pole body |
|
Discussions
- INTERPRETATION (RESOLVED): Keep the mitotic SPB half bridge narrower than the general SPB half bridge. GO:0061496 denotes the half bridge of the mitotic spindle pole body, is narrower than GO:0005825, and is part of the GO:0044732 mitotic spindle pole body.
- CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for mitotic half-bridge constituents. The first GO-backed mitotic half-bridge record captures the cell-cycle-specific substructure without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for its budding-yeast protein constituents.
Evidence
GO:0061496Gene Ontology cellular-component term for the half bridge of the mitotic spindle pole body.GO:0005825Gene Ontology parent term for the general half bridge of the spindle pole body.GO:0044732Gene Ontology cellular-component term for the mitotic spindle pole body that includes GO:0061496 by parthood.GO:0005816Gene Ontology cellular-component term for the broader spindle pole body.DOI:10.1146/annurev.cellbio.20.022003.114106Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.
Curation history
2026-09-29T09:14:08Zcodex · CREATED_RECORD — Scaffolded by scripts/new_record.py2026-09-29T09:15:11Zcodex · EXPANDED_RECORD — Added GO-backed half-bridge parentage and mitotic-SPB parthood, Saccharomyces scope, a mitotic duplication-site function, GO and literature evidence, a nonmechanistic mitotic half-bridge topology graph, and boundary/component discussions.
Source: data/structures/cytoskeleton/half_bridge_of_mitotic_spindle_pole_body.yaml