half bridge of spindle pole body
Structure adjacent to the plaques of the spindle pole body. [GO:0005825]
Part of: spindle pole body (GO:0005816)
Taxonomic distribution
NCBITaxon:4932Saccharomyces cerevisiae — COMMON: Budding yeast is a characterized fungal model in which SPB duplication starts at a half-bridge adjacent to the existing spindle pole body. [DOI:10.1146/annurev.cellbio.20.022003.114106]
Canonical examples
NCBITaxon:4932Saccharomyces cerevisiae — Budding-yeast reference system in which the layered SPB and its half-bridge-associated duplication pathway have been characterized. [DOI:10.1146/annurev.cellbio.20.022003.114106]
Functions
- spindle pole body duplication site — The half-bridge next to an existing budding-yeast SPB provides the site where new SPB assembly begins.
DOI:10.1146/annurev.cellbio.20.022003.114106Jaspersen and Winey 2004 reviewed the half-bridge-associated pathway for budding-yeast SPB duplication.
Mechanism graphs
Half-bridge site for new spindle pole body assembly (ASSEMBLY)
The half bridge is adjacent to the SPB plaques and marks where a new budding-yeast spindle pole body begins to assemble.
| Subject | Predicate | Object | Evidence |
|---|---|---|---|
| half bridge of spindle pole body | is part of | spindle pole body |
|
| half bridge of spindle pole body | templates assembly of | new spindle pole body |
|
Discussions
- INTERPRETATION (RESOLVED): Keep the spindle-pole-body half bridge distinct from the inner, central, and outer plaques. GO:0005825 denotes the half bridge adjacent to SPB plaques, while GO:0005822, GO:0005823, and GO:0005824 denote the nuclear inner, central, and cytoplasmic outer plaques.
- CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for half-bridge constituents. The first GO-backed half-bridge record captures the duplication-site substructure without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for the budding-yeast half-bridge proteins.
Evidence
GO:0005825Gene Ontology cellular-component term for the half bridge of the spindle pole body.GO:0005816Gene Ontology cellular-component term for the spindle pole body that includes the half bridge.GO:0005822Gene Ontology cellular-component term for the inner plaque of the spindle pole body.GO:0005823Gene Ontology cellular-component term for the central plaque of the spindle pole body.GO:0005824Gene Ontology cellular-component term for the outer plaque of the spindle pole body.DOI:10.1146/annurev.cellbio.20.022003.114106Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.
Curation history
2026-09-29T08:42:00Zcodex · CREATED_RECORD — Scaffolded by scripts/new_record.py2026-09-29T08:43:34Zcodex · EXPANDED_RECORD — Added spindle-pole-body parthood, Saccharomyces scope, a duplication-site function, GO and literature evidence, a nonmechanistic half-bridge topology graph, and plaque-boundary discussions.
Source: data/structures/cytoskeleton/half_bridge_of_spindle_pole_body.yaml