intermediate layer of mitotic spindle pole body

GO:0061498 · Cytoskeleton · Multiprotein complex · Proposed

The layer of the mitotic spindle pole body between the central plaque and the outer plaque. [GO:0061498]

Part of: mitotic spindle pole body (GO:0044732)

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast is a characterized fungal model for mitotic spindle-pole-body plaque topology, including the intermediate layer between the central and outer plaques. [DOI:10.1146/annurev.cellbio.20.022003.114106]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast reference system for the mitotic SPB and its layered cytoplasmic plaque side. [DOI:10.1146/annurev.cellbio.20.022003.114106]

The mitotic intermediate layer is a mitosis-specific SPB intermediate layer between the central and outer plaques.

Subject	Predicate	Object	Evidence
intermediate layer of mitotic spindle pole body	is a	intermediate layer of spindle pole body	`GO:0061498` GO:0061498 is_a GO:0005821 in the Gene Ontology cellular-component hierarchy.
intermediate layer of mitotic spindle pole body	is part of	mitotic spindle pole body	`GO:0061498` GO:0061498 defines the intermediate layer by its position in the mitotic spindle pole body.

INTERPRETATION (RESOLVED): Keep the mitotic SPB intermediate layer narrower than the general SPB intermediate layer. GO:0061498 denotes the intermediate layer of the mitotic spindle pole body, is narrower than GO:0005821, and is part of the GO:0044732 mitotic spindle pole body.
CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for mitotic SPB intermediate-layer constituents. The first GO-backed mitotic intermediate-layer record captures the cell-cycle-specific layer without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for budding-yeast protein constituents.

GO:0061498 Gene Ontology cellular-component term for the intermediate layer of the mitotic spindle pole body.
GO:0005821 Gene Ontology parent term for the general SPB intermediate layer.
GO:0044732 Gene Ontology cellular-component term for the mitotic spindle pole body that includes GO:0061498 by parthood.
GO:0005823 Gene Ontology cellular-component term for the central plaque of the spindle pole body.
GO:0005824 Gene Ontology cellular-component term for the outer plaque of the spindle pole body.
DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.

2026-09-29T10:10:00Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T10:10:48Z codex · EXPANDED_RECORD — Added GO-backed intermediate-layer parentage and mitotic-SPB parthood, Saccharomyces scope, GO and literature evidence, a nonmechanistic mitotic intermediate-layer topology graph, and boundary/component discussions.