meiotic spindle pole body

GO:0035974 · Cytoskeleton · Multiprotein complex · Proposed

The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome. [GO:0035974]

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding-yeast meiosis II spindle pole bodies remodel their cytoplasmic outer plaques into meiotic outer plaques that initiate prospore membrane assembly. [DOI:10.1093/emboj/19.14.3657]

NCBITaxon:4932 Saccharomyces cerevisiae — Reference fungal model in which meiosis II SPBs form meiotic outer plaques that dock prospore-membrane precursors. [DOI:10.1093/emboj/19.14.3657]

meiotic microtubule organization — Meiotic spindle pole bodies organize microtubules during the meiotic cell cycle.
- GO:0035974 GO:0035974 defines the meiotic spindle pole body as the microtubule-organizing center formed as part of the meiotic cell cycle.
prospore membrane initiation site — In budding yeast, meiosis II SPBs carry a meiotic outer plaque that nucleates prospore membrane formation.
- GO:0031322 GO:0031322 defines prospore-specific SPB remodeling as recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque.
- DOI:10.1093/emboj/19.14.3657 Knop and Strasser 2000 analyzed the budding-yeast SPB outer plaque as the assembly site for prospore membranes.

The meiotic SPB is a cell-cycle-specific SPB that carries a meiotic outer plaque for prospore membrane initiation in budding yeast.

Subject	Predicate	Object	Evidence
meiotic spindle pole body	is subtype of	spindle pole body	`GO:0035974` GO:0035974 is a cellular-component child of the general spindle pole body term. `GO:0005816` GO:0005816 identifies the broader fungal spindle pole body.
meiotic outer plaque	is part of	meiotic spindle pole body	`DOI:10.1093/emboj/19.14.3657` Knop and Strasser 2000 studied MOP formation on budding-yeast spindle pole bodies during meiosis.
meiotic outer plaque	anchors initiation of	prospore membrane	`GO:0031322` GO:0031322 describes outer-plaque remodeling into the meiotic outer plaque. `DOI:10.1093/emboj/19.14.3657` Knop and Strasser 2000 linked meiotic SPB remodeling to prospore membrane assembly.

INTERPRETATION (RESOLVED): Keep the meiotic spindle pole body narrower than the general fungal spindle pole body and distinct from the meiotic outer plaque substructure. GO:0035974 denotes the SPB formed as part of the meiotic cell cycle, while GO:0005816 covers the general fungal SPB. The locally minted meiotic outer plaque is a meiosis-II SPB substructure and prospore-membrane assembly site, not an equivalent name for the whole meiotic SPB.
CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for meiotic SPB and MOP constituents. This first GO-backed meiotic SPB record captures the named cell-cycle-specific structure without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for budding-yeast MOP or SPB-remodeling proteins.

GO:0035974 Gene Ontology cellular-component term for the meiotic spindle pole body.
GO:0005816 Gene Ontology parent term for the general fungal spindle pole body.
GO:0031322 Gene Ontology biological-process term for ascospore-type prospore-specific SPB remodeling; its definition names meiotic outer plaque formation.
GO:0005628 Gene Ontology cellular-component term for the prospore membrane that initiates from the meiotic outer plaque.
DOI:10.1093/emboj/19.14.3657 Knop and Strasser 2000, Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis, The EMBO Journal.

2026-09-29T14:42:11Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T14:44:19Z codex · EXPANDED_RECORD — Added GO-backed spindle-pole-body parentage, Saccharomyces scope, meiotic microtubule-organization and prospore-initiation functions, GO and literature evidence, a nonmechanistic MOP topology graph, and boundary/component discussions.