nuclear microtubule

GO:0005880 · Cytoskeleton · Filament · Proposed

Any microtubule in the nucleus of a cell. [GO:0005880]

Part of: nucleus (GO:0005634)

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast spindle pole bodies nucleate nuclear microtubules from their inner plaques. [DOI:10.1146/annurev.cellbio.20.022003.114106]

NCBITaxon:4932 Saccharomyces cerevisiae — Reference fungal model in which nuclear microtubules are organized by the nuclear face of the spindle pole body. [DOI:10.1146/annurev.cellbio.20.022003.114106]

nuclear microtubule array organization — Nuclear microtubules form non-cytoplasmic tubulin-polymer arrays that can be organized from nuclear microtubule-organizing centers such as the budding-yeast SPB inner plaque.
- GO:0005880 GO:0005880 defines nuclear microtubules as microtubules in the nucleus.
- DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004 reviewed the budding-yeast SPB inner plaque as the nuclear site for microtubule nucleation.

Budding-yeast spindle pole body inner plaques face the nucleus and organize nuclear microtubule nucleation.

Subject	Predicate	Object	Evidence
nuclear microtubule	is subtype of	microtubule	`GO:0005880` GO:0005880 is a cellular-component child of the generic microtubule term. `GO:0005874` GO:0005874 identifies the broader microtubule structure.
inner plaque of spindle pole body	organizes	nuclear microtubule	`DOI:10.1146/annurev.cellbio.20.022003.114106` Jaspersen and Winey 2004 reviewed the SPB inner plaque as the budding-yeast nuclear microtubule nucleation site.

INTERPRETATION (RESOLVED): Keep nuclear microtubules distinct from cytoplasmic microtubules and from array-specific spindle microtubules. GO:0005880 denotes microtubules in the nucleus and therefore differs from the cytoplasmic GO:0005881 class. It also differs from the GO:0005876 spindle microtubule class, which is defined by membership in a mitotic or meiotic spindle rather than by nuclear localization alone.
CURATION_TODO (OPEN): Resolve exact source-neutral groundings for nuclear microtubule-associated proteins and nucleation complexes. This first nuclear microtubule record captures the GO-backed tubulin-polymer subtype and defers taxon-specific motors, plus-end factors, and gamma-tubulin nucleation complexes.

GO:0005880 Gene Ontology cellular-component term for the nuclear microtubule.
GO:0005874 Gene Ontology cellular-component parent term for the microtubule.
GO:0005634 Gene Ontology cellular-component term for the nucleus.
GO:0005822 Gene Ontology cellular-component term for the budding-yeast SPB inner plaque that organizes nuclear microtubule nucleation.
GO:0005881 Gene Ontology cellular-component sibling term for cytoplasmic microtubules.
DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.

2026-09-29T13:34:12Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T13:35:16Z codex · EXPANDED_RECORD — Added GO microtubule parentage, nucleus parthood, Saccharomyces scope, a nuclear-array function, GO and literature evidence, a nonmechanistic SPB inner-plaque organization graph, and boundary/component discussions.