outer plaque of spindle pole body

GO:0005824 · Cytoskeleton · Multiprotein complex · Proposed

One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm. [GO:0005824]

Part of: spindle pole body (GO:0005816)

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: The outer plaque is directly evidenced as the cytoplasmic lamina of the budding-yeast spindle pole body; no broader fungal distribution is asserted in this first record. [DOI:10.1146/annurev.cellbio.20.022003.114106]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast reference system in which the layered spindle pole body and its cytoplasmic outer plaque have been characterized. [DOI:10.1146/annurev.cellbio.20.022003.114106]

cytoplasmic microtubule organization — The outer plaque is the cytoplasmic face of the budding-yeast SPB that organizes cytoplasmic microtubule nucleation.
- DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004 reviewed the budding-yeast SPB outer plaque as the cytoplasmic site for microtubule nucleation.

The outer plaque is the cytoplasmic laminate of the budding-yeast spindle pole body and organizes cytoplasmic microtubule nucleation.

Subject	Predicate	Object	Evidence
outer plaque of spindle pole body	is part of	spindle pole body	`GO:0005824` GO:0005824 defines the outer plaque as one of the laminate structures that form the spindle pole body.
outer plaque of spindle pole body	organizes	cytoplasmic microtubule	`DOI:10.1146/annurev.cellbio.20.022003.114106` Jaspersen and Winey 2004 reviewed the budding-yeast SPB outer plaque as the cytoplasmic site for microtubule nucleation.

INTERPRETATION (RESOLVED): Keep the spindle-pole-body outer plaque distinct from the prospore membrane attachment site and from the sporulation-specific meiotic outer plaque. GO:0005824 denotes a cytoplasmic laminate structure of the spindle pole body. The meiotic outer plaque nucleates prospore membrane formation in Saccharomyces, and GO:0070057 denotes the separate region of the prospore membrane to which the SPB is anchored.
CURATION_TODO (OPEN): Resolve exact source-neutral family groundings and the meiotic remodeling boundary for outer-plaque constituents. The first GO-backed outer-plaque record captures the lamina as a named SPB substructure without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for the budding-yeast plaque proteins and associated gamma-tubulin complexes.

GO:0005824 Gene Ontology cellular-component term for the outer plaque of the spindle pole body.
GO:0005816 Gene Ontology cellular-component term for the spindle pole body that includes the outer plaque.
GO:0005881 Gene Ontology cellular-component term for cytoplasmic microtubule, the structure organized by the outer plaque in the topology graph.
GO:0070057 Gene Ontology cellular-component term for the separate prospore membrane spindle pole body attachment site.
DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.
DOI:10.1093/emboj/19.14.3657 Knop and Strasser 2000, Role of the spindle pole body of yeast in mediating assembly of the prospore membrane during meiosis, The EMBO Journal.

2026-09-29T06:55:29Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-29T06:56:34Z codex · EXPANDED_RECORD — Added spindle-pole-body parthood, Saccharomyces scope, cytoplasmic microtubule-organization function, GO and literature evidence, a nonmechanistic topology graph, and plaque-boundary discussions.
2026-09-29T07:11:23Z codex · ADDRESSED_REVIEW — Resolved PR #1768 review issue #1769 by grounding the cytoplasmic microtubule graph node to GO:0005881 and using GO's canonical label.