spindle pole body duplication plaque

cellstructuremech:spindle_pole_body_duplication_plaque · Cytoskeleton · Multiprotein complex · Proposed

A transient cytoplasmic plaque intermediate formed after spindle pole body satellite expansion during daughter spindle pole body assembly in budding yeast. [DOI:10.1146/annurev.cellbio.20.022003.114106]

Synonyms: SPB duplication plaque

UniProt location names: UniProt Consortium, CC BY 4.0. Reference label and route sources.

Taxonomic distribution

• NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast is the characterized model in which satellite expansion forms a duplication plaque during daughter SPB assembly. [DOI:10.1146/annurev.cellbio.20.022003.114106]

Canonical examples

• NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast reference system for the SPB duplication plaque that follows the satellite intermediate in daughter SPB assembly. [DOI:10.1083/jcb.145.4.809]

Functions

• daughter spindle pole body plaque intermediate — The duplication plaque is an intermediate plaque in the transition from the SPB satellite to an inserted daughter spindle pole body.
  • DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004 reviewed budding-yeast SPB duplication as a pathway in which the satellite expands to a duplication plaque before the daughter SPB forms.

Mechanism graphs

Duplication plaque transition during daughter SPB assembly (ASSEMBLY)

During budding-yeast SPB duplication, the satellite expands into a duplication plaque before an inserted daughter SPB forms.

Discussions

• INTERPRETATION (RESOLVED): Keep the SPB duplication plaque distinct from the preceding satellite and the mature daughter spindle pole body. The duplication plaque is modeled as the transient plaque produced after satellite expansion, not as an exact synonym of the earlier SPB satellite or the final GO:0005816 spindle pole body.
• CURATION_TODO (OPEN): Resolve exact source-neutral family groundings for SPB duplication plaque constituents. The first SPB duplication plaque record captures the transient intermediate without guessing exact InterPro, Pfam, NCBIfam, or Complex Portal groundings for budding-yeast plaque constituents.

Evidence

• GO:0032991 Gene Ontology cellular-component term for protein-containing complex, used as the broader parent because GO does not provide an exact SPB duplication plaque term.
• GO:0005816 Gene Ontology cellular-component term for the mature spindle pole body produced after the budding-yeast duplication plaque stage.
• cellstructuremech:spindle_pole_body_satellite CellStructureMech record for the satellite precursor that expands into the duplication plaque.
• DOI:10.1083/jcb.145.4.809 Adams and Kilmartin 1999, Localization of core spindle pole body components during spindle pole body duplication in Saccharomyces cerevisiae, Journal of Cell Biology.
• DOI:10.1534/genetics.111.128710 Winey and Bloom 2012, Mitotic spindle form and function, Genetics.
• DOI:10.1146/annurev.cellbio.20.022003.114106 Jaspersen and Winey 2004, The budding yeast spindle pole body: structure, duplication, and function, Annual Review of Cell and Developmental Biology.

Curation history

• 2026-09-29T11:35:12Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
• 2026-09-29T11:35:55Z codex · EXPANDED_RECORD — Added SPB duplication plaque synonymy, protein-containing-complex parentage, Saccharomyces scope, a daughter-SPB plaque-intermediate function, GO and literature evidence, a nonmechanistic duplication-plaque transition graph, and boundary/component discussions.
• 2026-09-29T11:50:45Z codex · ADDRESSED_REVIEW — Resolved PR #1780 review issue #1781 by tightening the SPB duplication plaque precursor edge evidence to mention the duplication plaque intermediate directly.

Source: data/structures/cytoskeleton/spindle_pole_body_duplication_plaque.yaml