sno(s)RNA-containing ribonucleoprotein complex

GO:0005732 · Ribonucleoprotein · Ribonucleoprotein complex · Proposed

A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA. [GO:0005732]

UniProt location names: UniProt Consortium, CC BY 4.0. Reference label and route sources.

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
sno(s)RNA	Rna	part of	Reviewed label only (reviewed name; no accession asserted)				Small nucleolar or small RNA-family RNA constituent that defines a sno(s)RNA-containing ribonucleoprotein complex. `GO:0005732` GO:0005732 defines sno(s)RNA-containing ribonucleoprotein complexes as containing a snoRNA-family RNA molecule and associated proteins.
sno(s)RNP-associated proteins	Protein	part of	Reviewed label only (reviewed name; no accession asserted)				Protein constituents associated with snoRNA-family RNAs in sno(s)RNA-containing ribonucleoprotein complexes. `GO:0005732` GO:0005732 defines sno(s)RNA-containing ribonucleoprotein complexes as containing associated proteins in addition to a snoRNA-family RNA molecule.

Mechanism graphs

sno(s)RNA and associated proteins form sno(s)RNPs (ASSEMBLY)

sno(s)RNA-containing ribonucleoprotein complexes contain an RNA of the snoRNA family together with associated proteins.

Subject	Predicate	Object	Evidence
sno(s)RNA	contributes constituents to	sno(s)RNA-containing ribonucleoprotein complex	`GO:0005732` GO:0005732 defines the complex as containing an RNA molecule of the snoRNA family.
sno(s)RNP-associated proteins	contributes constituents to	sno(s)RNA-containing ribonucleoprotein complex	`GO:0005732` GO:0005732 defines the complex as containing associated proteins.

Discussions

CURATION_TODO (OPEN): Resolve exact source-neutral RNA and protein-family boundaries for sno(s)RNA-containing RNP subclasses. The first GO:0005732 record captures only the GO-defined RNA and associated-protein cohorts. Exact box C/D, box H/ACA, telomerase-RNA and ribonuclease-MRP subfamily boundaries should be resolved before expanding the component list.

Evidence

GO:0005732 Gene Ontology cellular-component term for sno(s)RNA-containing ribonucleoprotein complex.
GO:1990904 Gene Ontology cellular-component parent term for ribonucleoprotein complex.

Curation history

2026-09-25T11:55:49Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-25T11:56:25Z codex · EXPANDED_RECORD — Added ribonucleoprotein-complex parentage, reviewed-label-only sno(s)RNA and sno(s)RNP-associated protein components, a conservative constituent graph and a TODO for exact sno(s)RNP subclass boundaries.

Source: data/structures/ribonucleoprotein/sno_s_rna_containing_ribonucleoprotein_complex.yaml