U7 snRNP
A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs. [GO:0005683]
Synonyms: snRNP U7
Components
| Component | Type | Part of / acts on | Grounding | Genes | Stoichiometry | Essential | Role |
|---|---|---|---|---|---|---|---|
| U7 snRNA | Rna | part of | SO:0002338 | U7 small nuclear RNA constituent named in the U7 snRNP definition and grounded to the U7 snRNA Sequence Ontology term.
|
Mechanism graphs
U7 snRNA is a U7 snRNP constituent (ASSEMBLY)
The U7 snRNP contains U7 small nuclear RNA.
| Subject | Predicate | Object | Evidence |
|---|---|---|---|
| U7 snRNA | contributes constituents to | U7 snRNP |
|
Discussions
- CURATION_TODO (OPEN): Resolve exact source-neutral protein components that form the U7 snRNP. The first GO:0005683 record captures U7 snRNA, which defines the U7 snRNP in GO. Protein-family and subcomplex boundaries should be resolved before expanding this component list.
Evidence
GO:0005683Gene Ontology cellular-component term for the U7 snRNP and its exact synonym.GO:0030532Gene Ontology cellular-component parent term for small nuclear ribonucleoprotein complex.SO:0002338Sequence Ontology term for U7 snRNA.DOI:10.1073/pnas.1533509100Dominski, Yang, Purdy and Marzluff 2003, Cloning and characterization of the Drosophila U7 small nuclear RNA, Proceedings of the National Academy of Sciences of the United States of America.PMID:12872004PubMed identifier for Dominski, Yang, Purdy and Marzluff 2003 as reported by NCBI E-utilities.
Curation history
2026-09-25T03:08:30Zcodex · CREATED_RECORD — Scaffolded by scripts/new_record.py2026-09-25T03:09:06Zcodex · EXPANDED_RECORD — Added the GO exact synonym, small nuclear RNP parentage, the SO-grounded U7 snRNA component, Dominski/Yang/Purdy/Marzluff U7 snRNA evidence, a minimal U7 snRNA constituent graph and a protein-component grounding TODO.