All families / PF01865
PF01865: PhoU_div
Protein of unknown function DUF47
- Curation status
- SEEDED
- Seed status
- EX DUF
- Characterization
- UNSCORED
Grounding
PF01865: Protein of unknown function DUF47
IPR018445: integrated entry for Protein of unknown function DUF47
Source description
This family includes prokaryotic proteins of unknown function, as well as a protein annotated as the pit accessory protein from Sinorhizobium meliloti O30498 (UniProtKB protein). However, the function of this protein is also unknown (Pit stands for Phosphate transport). It is probably distantly related to PF01895 (PhoU domain) (personal obs:Yeats C).
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
2 verified sequence examples. FASTA
| UniProt | Protein / organism | Sequence | Provenance |
|---|---|---|---|
| O34454 | UPF0111 protein YkaA Bacillus subtilis (strain 168) | 205 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q58046 | UPF0111 protein MJ0629 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | 214 aa; version 1 UniProt 2026_03 | PTM REGISTRY MIRROR |
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 9,082
- matches
- 9,082
- proteomes
- 8,245
- taxa
- 11,416
- structures
- 3
- alphafold models
- 5,897
- domain architectures
- 10
Classification basis
name matches duf; name says unknown function; description says unknown function; pfam previous unknown name
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| PhoU_div (PF01865) | ProteinTraitsMech | TIGR00153 family protein | Q58046 UPF0111 protein MJ0629 | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | Protein of unknown function DUF47 | O34454 UPF0111 protein YkaA | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | Protein of unknown function DUF47 | Q58046 UPF0111 protein MJ0629 | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | Protein of unknown function DUF47 | trait identifier | |
| PhoU_div (PF01865) | ProteinTraitsMech | PhoU-like domain superfamily | O34454 UPF0111 protein YkaA | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | PhoU-like domain superfamily | Q58046 UPF0111 protein MJ0629 | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | Phosphate transport system protein phou homolog 2; domain 2 | O34454 UPF0111 protein YkaA | canonical example family classification |
| PhoU_div (PF01865) | ProteinTraitsMech | Phosphate transport system protein phou homolog 2; domain 2 | Q58046 UPF0111 protein MJ0629 | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.