DUFMech

All families / PF02641

PF02641: DUF190

Uncharacterized ACR, COG1993

Curation status
SEEDED
Seed status
KNOWN HISTORICAL DUF
Characterization
UNSCORED

Grounding

PF02641: Uncharacterized ACR, COG1993
IPR003793: integrated entry for Uncharacterized ACR, COG1993

Source description

No description supplied.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

3 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
Q9FC38UPF0166 protein SCO7045
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)		114 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9V0X3UPF0166 protein PYRAB06660
Pyrococcus abyssi (strain GE5 / Orsay)		127 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9WXM9UPF0166 protein TM_0021
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)		102 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
3,378
matches
3,851
proteomes
2,906
taxa
4,805
structures
2
alphafold models
2,250
domain architectures
13

Classification basis

short name matches duf

No scoring reasons supplied.

Related Mech records

FamilyMechRecordProteinLink basis
DUF190 (PF02641)ProteinTraitsMechUncharacterized ACR, COG1993Q9FC38
UPF0166 protein SCO7045		canonical example family classification
DUF190 (PF02641)ProteinTraitsMechUncharacterized ACR, COG1993Q9V0X3
UPF0166 protein PYRAB06660		canonical example family classification
DUF190 (PF02641)ProteinTraitsMechUncharacterized ACR, COG1993Q9WXM9
UPF0166 protein TM_0021		canonical example family classification
DUF190 (PF02641)ProteinTraitsMechUncharacterized ACR, COG1993
trait identifier

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF02641.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.