All families / PF02656
PF02656: DUF202
Domain of unknown function (DUF202)
- Curation status
- SEEDED
- Seed status
- UNKNOWN CANDIDATE
- Characterization
- UNSCORED
Grounding
PF02656: Domain of unknown function (DUF202)
IPR003807: integrated entry for Domain of unknown function (DUF202)
Source description
This family consists of hypothetical proteins some of which are putative membrane proteins. No functional information or experimental verification of function is known. This domain is around 100 amino acids long.
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
6 verified sequence examples. FASTA
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 18,669
- matches
- 18,687
- proteomes
- 7,356
- taxa
- 11,815
- structures
- 3
- alphafold models
- 13,291
- domain architectures
- 173
Classification basis
short name matches duf; name says unknown function; domain of unknown function
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| DUF202 (PF02656) | ProteinTraitsMech | fungal-type vacuole membrane | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuolar transporter chaperone complex | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuolar transporter chaperone complex | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuolar transporter chaperone complex | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuolar transporter chaperone complex | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate kinase activity | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | engulfment of target by autophagosome | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | engulfment of target by autophagosome | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | engulfment of target by autophagosome | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | engulfment of target by autophagosome | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | microautophagy | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate biosynthetic process | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate biosynthetic process | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate biosynthetic process | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate biosynthetic process | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate metabolic process | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate metabolic process | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate metabolic process | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | polyphosphate metabolic process | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuolar transport | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | vacuole fusion, non-autophagic | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | PolyPPase_VTC4_like | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | PolyPPase_VTC2-3_like | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | PolyPPase_VTC2-3_like | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | SPX_VTC2_like | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | SPX_VTC2_like | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | SPX_VTC2_like | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | P0ADL6 Inner membrane protein YidG | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | P0ADM0 Inner membrane protein YidH | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function DUF202 | trait identifier | |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function (DUF202) | P40046 Vacuolar transporter chaperone complex subunit 1 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function (DUF202) | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function (DUF202) | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | Domain of unknown function (DUF202) | trait identifier | |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain superfamily | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain superfamily | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC domain superfamily | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC, catalytic tunnel domain | P43585 Vacuolar transporter chaperone complex subunit 2 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC, catalytic tunnel domain | P47075 Vacuolar transporter chaperone complex subunit 4 | canonical example family classification |
| DUF202 (PF02656) | ProteinTraitsMech | VTC, catalytic tunnel domain | Q02725 Vacuolar transporter chaperone 3 complex subunit 3 | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.