DUFMech

All families / PF04862

PF04862: DUF642

Protein of unknown function (DUF642)

Curation status
SEEDED
Seed status
UNKNOWN CANDIDATE
Characterization
UNSCORED

Grounding

PF04862: Protein of unknown function (DUF642)
IPR006946: integrated entry for Protein of unknown function (DUF642)

Source description

This family represents a duplicated conserved region found in a number of uncharacterised plant proteins, potentially in the stem. There is a conserved CGP sequence motif.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

5 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
O22940Protein TEEBE
Arabidopsis thaliana
370 aa; version 1
UniProt 2026_03
PTM REGISTRY MIRROR
6 sibling references
Q8LAR0Protein BIIDXI
Arabidopsis thaliana
365 aa; version 1
UniProt 2026_03
UNIPROT FETCH
14 sibling references
Q94F20Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
Arabidopsis thaliana
369 aa; version 1
UniProt 2026_03
UNIPROT FETCH
4 sibling references
Q9LYE7BIIDXI-like protein At5g11420
Arabidopsis thaliana
366 aa; version 1
UniProt 2026_03
UNIPROT FETCH
3 sibling references
Q9SSB7Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1
Arabidopsis thaliana
370 aa; version 1
UniProt 2026_03
UNIPROT FETCH
1 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
4,558
matches
8,102
proteomes
970
taxa
2,286
structures
0
alphafold models
3,516
domain architectures
197

Classification basis

short name matches duf; name says unknown function

No scoring reasons supplied.

Related Mech records

FamilyMechRecordProteinLink basis
DUF642 (PF04862)ProteinTraitsMechplant-type cell wallQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechenzyme regulator activityQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechembryonic morphogenesisQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechgravitropismQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechnegative regulation of unidimensional cell growthO22940
Protein TEEBE
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechpectin biosynthetic processQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechplant-type cell wall organizationQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechregulation of cell wall pectin metabolic processO22940
Protein TEEBE
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechregulation of cell wall pectin metabolic processQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechregulation of cell wall pectin metabolic processQ94F20
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechregulation of cell wall pectin metabolic processQ9LYE7
BIIDXI-like protein At5g11420
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechregulation of plant organ morphogenesisQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechreproductive structure developmentQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechresponse to gibberellinQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechseed germinationQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domainO22940
Protein TEEBE
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domainQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domainQ94F20
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domainQ9LYE7
BIIDXI-like protein At5g11420
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domainQ9SSB7
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechDUF642 L-galactono-1,4-lactone-responsive gene 2-like domain
trait identifier
DUF642 (PF04862)ProteinTraitsMechProtein of unknown function (DUF642)O22940
Protein TEEBE
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechProtein of unknown function (DUF642)Q8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechProtein of unknown function (DUF642)Q94F20
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechProtein of unknown function (DUF642)
trait identifier
DUF642 (PF04862)ProteinTraitsMechGalactose-binding-like domain superfamilyO22940
Protein TEEBE
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechGalactose-binding-like domain superfamilyQ8LAR0
Protein BIIDXI
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechGalactose-binding-like domain superfamilyQ94F20
Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
canonical example family classification
DUF642 (PF04862)ProteinTraitsMechGalactose-binding-like domain superfamilyQ9LYE7
BIIDXI-like protein At5g11420
canonical example family classification

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF04862.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.