All families / PF04862
PF04862: DUF642
Protein of unknown function (DUF642)
- Curation status
- SEEDED
- Seed status
- UNKNOWN CANDIDATE
- Characterization
- UNSCORED
Grounding
PF04862: Protein of unknown function (DUF642)
IPR006946: integrated entry for Protein of unknown function (DUF642)
Source description
This family represents a duplicated conserved region found in a number of uncharacterised plant proteins, potentially in the stem. There is a conserved CGP sequence motif.
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
5 verified sequence examples. FASTA
| UniProt | Protein / organism | Sequence | Provenance |
|---|---|---|---|
| O22940 | Protein TEEBE Arabidopsis thaliana | 370 aa; version 1 UniProt 2026_03 | PTM REGISTRY MIRROR |
| Q8LAR0 | Protein BIIDXI Arabidopsis thaliana | 365 aa; version 1 UniProt 2026_03 | UNIPROT FETCH14 sibling references
|
| Q94F20 | Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2 Arabidopsis thaliana | 369 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q9LYE7 | BIIDXI-like protein At5g11420 Arabidopsis thaliana | 366 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q9SSB7 | Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1 Arabidopsis thaliana | 370 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 4,558
- matches
- 8,102
- proteomes
- 970
- taxa
- 2,286
- structures
- 0
- alphafold models
- 3,516
- domain architectures
- 197
Classification basis
short name matches duf; name says unknown function
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| DUF642 (PF04862) | ProteinTraitsMech | plant-type cell wall | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | enzyme regulator activity | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | embryonic morphogenesis | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | gravitropism | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | negative regulation of unidimensional cell growth | O22940 Protein TEEBE | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | pectin biosynthetic process | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | plant-type cell wall organization | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | regulation of cell wall pectin metabolic process | O22940 Protein TEEBE | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | regulation of cell wall pectin metabolic process | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | regulation of cell wall pectin metabolic process | Q94F20 Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | regulation of cell wall pectin metabolic process | Q9LYE7 BIIDXI-like protein At5g11420 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | regulation of plant organ morphogenesis | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | reproductive structure development | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | response to gibberellin | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | seed germination | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | O22940 Protein TEEBE | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | Q94F20 Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | Q9LYE7 BIIDXI-like protein At5g11420 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | Q9SSB7 Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | DUF642 L-galactono-1,4-lactone-responsive gene 2-like domain | trait identifier | |
| DUF642 (PF04862) | ProteinTraitsMech | Protein of unknown function (DUF642) | O22940 Protein TEEBE | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Protein of unknown function (DUF642) | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Protein of unknown function (DUF642) | Q94F20 Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Protein of unknown function (DUF642) | trait identifier | |
| DUF642 (PF04862) | ProteinTraitsMech | Galactose-binding-like domain superfamily | O22940 Protein TEEBE | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Galactose-binding-like domain superfamily | Q8LAR0 Protein BIIDXI | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Galactose-binding-like domain superfamily | Q94F20 Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2 | canonical example family classification |
| DUF642 (PF04862) | ProteinTraitsMech | Galactose-binding-like domain superfamily | Q9LYE7 BIIDXI-like protein At5g11420 | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.