DUFMech

All families / PF06071

PF06071: YchF-GTPase_C

Protein of unknown function (DUF933)

Curation status
SEEDED
Seed status
EX DUF
Characterization
UNSCORED

Grounding

PF06071: Protein of unknown function (DUF933)
IPR013029: integrated entry for Protein of unknown function (DUF933)

Source description

This domain is found at the C terminus of the YchF GTP-binding protein (O13998 (UniProtKB protein)) and is possibly related to the ubiquitin-like and MoaD/ThiS superfamilies.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

8 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
P0ABU2Ribosome-binding ATPase YchF
Escherichia coli (strain K12)		363 aa; version 2
UniProt 2026_03		PTM REGISTRY MIRROR
2 sibling references
P37518Ribosome-binding ATPase YchF
Bacillus subtilis (strain 168)		366 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
P38219Obg-like ATPase 1
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)		394 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
P38746Obg-like ATPase homolog
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)		405 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
P91917Obg-like ATPase 1
Caenorhabditis elegans		395 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9CZ30Obg-like ATPase 1
Mus musculus		396 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9NTK5Obg-like ATPase 1
Homo sapiens		396 aa; version 2
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9SA73Obg-like ATPase 1
Arabidopsis thaliana		394 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
23,701
matches
23,716
proteomes
20,956
taxa
34,445
structures
12
alphafold models
16,566
domain architectures
137

Classification basis

name matches duf; name says unknown function; pfam previous unknown name

No scoring reasons supplied.

Related Mech records

FamilyMechRecordProteinLink basis
YchF-GTPase_C (PF06071)ProteinTraitsMechYchF, C-terminal domain
trait identifier
YchF-GTPase_C (PF06071)ProteinTraitsMechProtein of unknown function (DUF933)
trait identifier

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF06071.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.