All families / PF10035
PF10035: DUF2179
Uncharacterized protein conserved in bacteria (DUF2179)
- Curation status
- SEEDED
- Seed status
- KNOWN HISTORICAL DUF
- Characterization
- UNSCORED
Grounding
PF10035: Uncharacterized protein conserved in bacteria (DUF2179)
IPR019264: integrated entry for Uncharacterized protein conserved in bacteria (DUF2179)
Source description
This domain, found in various hypothetical bacterial proteins, has no known function.
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
9 verified sequence examples. FASTA
| UniProt | Protein / organism | Sequence | Provenance |
|---|---|---|---|
| A1SUM3 | UPF0316 protein Ping_1367 Psychromonas ingrahamii (strain DSM 17664 / CCUG 51855 / 37) | 179 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
| A8MLK3 | UPF0316 protein Clos_0555 Alkaliphilus oremlandii (strain OhILAs) | 172 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
| O34624 | UPF0316 protein YebE Bacillus subtilis (strain 168) | 184 aa; version 2 UniProt 2026_03 | PTM REGISTRY MIRROR |
| O34792 | UPF0750 membrane protein YvjA Bacillus subtilis (strain 168) | 281 aa; version 1 UniProt 2026_03 | PTM REGISTRY MIRROR |
| P39803 | UPF0750 membrane protein YitT Bacillus subtilis (strain 168) | 280 aa; version 2 UniProt 2026_03 | UNIPROT FETCH |
| P42978 | UPF0750 membrane protein YpjC Bacillus subtilis (strain 168) | 290 aa; version 2 UniProt 2026_03 | UNIPROT FETCH |
| P54478 | UPF0750 membrane protein YqfU Bacillus subtilis (strain 168) | 293 aa; version 2 UniProt 2026_03 | UNIPROT FETCH |
| P94357 | UPF0750 membrane protein YxkD Bacillus subtilis (strain 168) | 278 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| P96672 | UPF0750 membrane protein YdeO Bacillus subtilis (strain 168) | 290 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 15,886
- matches
- 15,886
- proteomes
- 5,206
- taxa
- 8,097
- structures
- 1
- alphafold models
- 10,419
- domain architectures
- 11
Classification basis
short name matches duf
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| DUF2179 (PF10035) | ProteinTraitsMech | hypothetical protein | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | O34792 UPF0750 membrane protein YvjA | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | P39803 UPF0750 membrane protein YitT | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | P42978 UPF0750 membrane protein YpjC | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | P54478 UPF0750 membrane protein YqfU | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | P94357 UPF0750 membrane protein YxkD | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C | P96672 UPF0750 membrane protein YdeO | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | YitT_C_like_1 | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | O34792 UPF0750 membrane protein YvjA | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | P39803 UPF0750 membrane protein YitT | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | P42978 UPF0750 membrane protein YpjC | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | P54478 UPF0750 membrane protein YqfU | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | P94357 UPF0750 membrane protein YxkD | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | P96672 UPF0750 membrane protein YdeO | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF2179 | trait identifier | |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function DUF5698 | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterized protein conserved in bacteria (DUF2179) | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterized protein conserved in bacteria (DUF2179) | O34792 UPF0750 membrane protein YvjA | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterized protein conserved in bacteria (DUF2179) | P39803 UPF0750 membrane protein YitT | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterized protein conserved in bacteria (DUF2179) | trait identifier | |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function (DUF5698) | A1SUM3 UPF0316 protein Ping_1367 | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function (DUF5698) | A8MLK3 UPF0316 protein Clos_0555 | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Domain of unknown function (DUF5698) | O34624 UPF0316 protein YebE | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | O34792 UPF0750 membrane protein YvjA | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | P39803 UPF0750 membrane protein YitT | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | P42978 UPF0750 membrane protein YpjC | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | P54478 UPF0750 membrane protein YqfU | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | P94357 UPF0750 membrane protein YxkD | canonical example family classification |
| DUF2179 (PF10035) | ProteinTraitsMech | Uncharacterised 5xTM membrane BCR, YitT family COG1284 | P96672 UPF0750 membrane protein YdeO | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.