All families / PF13334
PF13334: DUF4094
Domain of unknown function (DUF4094)
- Curation status
- SEEDED
- Seed status
- UNKNOWN CANDIDATE
- Characterization
- UNSCORED
Grounding
PF13334: Domain of unknown function (DUF4094)
IPR025298: integrated entry for Domain of unknown function (DUF4094)
Source description
This domain is found in plant proteins that often carry a galactosyltransferase domain, PF01762 (Pfam entry), at their C-terminus.
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
9 verified sequence examples. FASTA
| UniProt | Protein / organism | Sequence | Provenance |
|---|---|---|---|
| A8MRC7 | Probable beta-1,3-galactosyltransferase 2 Arabidopsis thaliana | 407 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
| Q5XEZ1 | Hydroxyproline O-galactosyltransferase HPGT3 Arabidopsis thaliana | 346 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q6NQB7 | Beta-1,3-galactosyltransferase 7 Arabidopsis thaliana | 393 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
| Q8LEJ9 | Probable beta-1,3-galactosyltransferase 4 Arabidopsis thaliana | 407 aa; version 1 UniProt 2026_03 | UNIPROT FETCH1 sibling references |
| Q94A05 | Hydroxyproline O-galactosyltransferase HPGT2 Arabidopsis thaliana | 345 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q94F27 | Hydroxyproline O-galactosyltransferase HPGT1 Arabidopsis thaliana | 338 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q9C809 | Probable beta-1,3-galactosyltransferase 8 Arabidopsis thaliana | 395 aa; version 1 UniProt 2026_03 | UNIPROT FETCH |
| Q9LM60 | Probable beta-1,3-galactosyltransferase 5 Arabidopsis thaliana | 398 aa; version 1 UniProt 2026_03 | UNIPROT FETCH2 sibling references |
| Q9MAP8 | Beta-1,6-galactosyltransferase GALT31A Arabidopsis thaliana | 399 aa; version 1 UniProt 2026_03 | UNIPROT FETCH2 sibling references |
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 5,074
- matches
- 5,097
- proteomes
- 381
- taxa
- 1,069
- structures
- 0
- alphafold models
- 4,046
- domain architectures
- 75
Classification basis
short name matches duf; name says unknown function; domain of unknown function
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| DUF4094 (PF13334) | ProteinTraitsMech | Golgi membrane | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | beta-1,3-galactosyltransferase activity | Q6NQB7 Beta-1,3-galactosyltransferase 7 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | beta-1,3-galactosyltransferase activity | Q9C809 Probable beta-1,3-galactosyltransferase 8 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | beta-1,3-galactosyltransferase activity | Q9LM60 Probable beta-1,3-galactosyltransferase 5 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | galactosyltransferase activity | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | hydroxyproline O-galactosyltransferase activity | Q5XEZ1 Hydroxyproline O-galactosyltransferase HPGT3 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | hydroxyproline O-galactosyltransferase activity | Q94A05 Hydroxyproline O-galactosyltransferase HPGT2 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | hydroxyproline O-galactosyltransferase activity | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | arabinogalactan protein metabolic process | Q5XEZ1 Hydroxyproline O-galactosyltransferase HPGT3 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | arabinogalactan protein metabolic process | Q94A05 Hydroxyproline O-galactosyltransferase HPGT2 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | arabinogalactan protein metabolic process | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | non-classical arabinogalactan protein metabolic process | Q9C809 Probable beta-1,3-galactosyltransferase 8 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | pollen wall assembly | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | protein O-linked glycosylation via galactose | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | A8MRC7 Probable beta-1,3-galactosyltransferase 2 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q5XEZ1 Hydroxyproline O-galactosyltransferase HPGT3 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q8LEJ9 Probable beta-1,3-galactosyltransferase 4 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q94A05 Hydroxyproline O-galactosyltransferase HPGT2 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q9C809 Probable beta-1,3-galactosyltransferase 8 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q9LM60 Probable beta-1,3-galactosyltransferase 5 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | Q9MAP8 Beta-1,6-galactosyltransferase GALT31A | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function DUF4094 | trait identifier | |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function (DUF4094) | Q5XEZ1 Hydroxyproline O-galactosyltransferase HPGT3 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function (DUF4094) | Q94A05 Hydroxyproline O-galactosyltransferase HPGT2 | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function (DUF4094) | Q9MAP8 Beta-1,6-galactosyltransferase GALT31A | canonical example family classification |
| DUF4094 (PF13334) | ProteinTraitsMech | Domain of unknown function (DUF4094) | trait identifier | |
| DUF4094 (PF13334) | ProteinTraitsMech | CATH homologous superfamily 3.90.550.50 | Q94F27 Hydroxyproline O-galactosyltransferase HPGT1 | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.