All families / PF20784
PF20784: DUF5575_C
DUF5575 C-terminal domain
- Curation status
- SEEDED
- Seed status
- KNOWN HISTORICAL DUF
- Characterization
- UNSCORED
Grounding
PF20784: DUF5575 C-terminal domain
IPR049218: integrated entry for DUF5575 C-terminal domain
Source description
This entry represents the C-terminal domain from a family of Chordate proteins that includes C19orf68. These proteins appear to be transposon related.
Evidence and references
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
2 verified sequence examples. FASTA
| UniProt | Protein / organism | Sequence | Provenance |
|---|---|---|---|
| Q6DI92 | Uncharacterized protein ZSWIM9 Mus musculus | 447 aa; version 2 UniProt 2026_03 | UNIPROT FETCH |
| Q86XI8 | Uncharacterized protein ZSWIM9 Homo sapiens | 627 aa; version 2 UniProt 2026_03 | UNIPROT FETCH |
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 368
- matches
- 436
- proteomes
- 193
- taxa
- 792
- structures
- 0
- alphafold models
- 251
- domain architectures
- 34
Classification basis
name matches duf
No scoring reasons supplied.
Related Mech records
| Family | Mech | Record | Protein | Link basis |
|---|---|---|---|---|
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575, C-terminal domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575, C-terminal domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575, C-terminal domain | trait identifier | |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575, N-terminal domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575, N-terminal domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | ZSWIM9, central RNaseH-like domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | ZSWIM9, central RNaseH-like domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 C-terminal domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 C-terminal domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 C-terminal domain | trait identifier | |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 N-terminal domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 N-terminal domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 central RNaseH like domain | Q6DI92 Uncharacterized protein ZSWIM9 | canonical example family classification |
| DUF5575_C (PF20784) | ProteinTraitsMech | DUF5575 central RNaseH like domain | Q86XI8 Uncharacterized protein ZSWIM9 | canonical example family classification |
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.