NaturalProductMech

lividomycin A

CHEBI:71961 EXACT SEEDED antimycobacterial

A member of the class of lividomycins that is lividomycin B in which position 4 of the diamino-L-idopyranosyl moiety has been converted into its α-D-mannopyranoside.

Structure

Standard InChIKeyDBLVDAUGBTYDFR-SWMBIRFSSA-N
SMILESC1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H](C[C@@H]([C@H](O2)CO)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O[C@@H]5[C@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)O)N)O)O)N
Stereochemistryfully defined
Cross-referencespubchem:72394

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces lividus
NCBITaxon:282216
SOURCE_ASSERTION mibig:BGC0000708 PMID:19362651

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces lividus
NCBITaxon:282216
LOTUS DOI:10.7164/ANTIBIOTICS.24.333

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000708 Streptomyces lividus
NCBITaxon:282216
CLUSTER_UNSTATED genbank:AJ748832.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Bioactivities 1

AssayResultReference
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose DatabaseACTIVEpubchem.aid:1195

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0000708MIBIG5
CHEBI:71961CHEBI3-star

This page is generated from data/natural_products/carbohydrates/lividomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.