lividomycin A

CHEBI:71961 EXACT SEEDED antimycobacterial

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

A member of the class of lividomycins that is lividomycin B in which position 4 of the diamino-L-idopyranosyl moiety has been converted into its α-D-mannopyranoside.

Structure

Standard InChIKey	DBLVDAUGBTYDFR-SWMBIRFSSA-N
SMILES	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H](C[C@@H]([C@H](O2)CO)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O[C@@H]5[C@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)O)N)O)O)N
Stereochemistry	fully defined
Cross-references	pubchem:72394

Filing pathway

Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Streptomyces lividus NCBITaxon:282216	SOURCE_ASSERTION	mibig:BGC0000708	PMID:19362651

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Streptomyces lividus NCBITaxon:282216	LOTUS	DOI:10.7164/ANTIBIOTICS.24.333

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0000708	Streptomyces lividus NCBITaxon:282216	CLUSTER_UNSTATED	genbank:AJ748832.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Bioactivities 1

Entries preserve source qualifiers, targets and evidence. Repeated assay names or values are not independent replications; inspect source detail for differences.

Assay	Result	Target enzyme	Source detail
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database	ACTIVE	Not recorded	pubchem.aid:1195 assay DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database evidence reference pubchem.aid:1195 evidence type DATABASE_ASSERTION notes PubChem BioAssay AID 1195, deposited by EPA DSSTox; assay type Other. call ACTIVE

Elsewhere in the fleet

AntibioticMech — CHEBI:71961 (same structure, same inchikey)

Explore across X-Mech

AntibioticMech (lividomycin A) ↗ MediaIngredientMech (CHEBI:71961) ↗ TaxonMech: Streptomyces lividus (NCBITaxon:282216) ↗ PathwayMech (mibig:BGC0000708) ↗

Provenance

Source concept	Source	Version
BGC0000708	MIBIG	5
CHEBI:71961	CHEBI	3-star

This page is generated from data/natural_products/carbohydrates/lividomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.