ribostamycin
CHEBI:45257 EXACT SEEDED antibacterial
An amino cyclitol glycoside that is 4,6-diaminocyclohexane-1,2,3-triol having a 2,6-diamino-2,6-dideoxy-α-D-glucosyl residue attached at position 1 and a β-D-ribosyl residue attached at position 2. It is an antibiotic produced by Streptomyces ribosidificus (formerly S. thermoflavus).
Structure
| Standard InChIKey | NSKGQURZWSPSBC-VVPCINPTSA-N |
|---|---|
| SMILES | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O)N |
| Stereochemistry | fully defined |
| Cross-references | pubchem:33042 |
Filing pathway
Carbohydrates — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces ribosidificus NCBITaxon:80859 |
SOURCE_ASSERTION | mibig:BGC0000713 | PMID:16258246 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces fradiae NCBITaxon:1906 |
LOTUS | DOI:10.1016/S0021-9673(00)94512-6 |
| Streptomyces ribosidificus NCBITaxon:80859 |
LOTUS | DOI:10.1016/0378-1119(88)90031-5 |
| Streptomyces ribosidificus NCBITaxon:80859 |
LOTUS | DOI:10.1271/BBB1961.39.1593 |
| Streptomyces ribosidificus NCBITaxon:80859 |
LOTUS | DOI:10.7164/ANTIBIOTICS.23.173 |
| Streptomyces ribosidificus NCBITaxon:80859 |
LOTUS | DOI:10.7164/ANTIBIOTICS.28.42 |
| Streptomyces ribosidificus NCBITaxon:80859 |
LOTUS | DOI:10.7164/ANTIBIOTICS.45.1167 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000713 | Streptomyces ribosidificus NCBITaxon:80859 |
CLUSTER_UNSTATED | genbank:AJ748131.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:45257 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000713 | MIBIG | 5 |
| CHEBI:45257 | CHEBI | 3-star |
This page is generated from data/natural_products/carbohydrates/ribostamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.