bikaverin
CHEBI:3096 EXACT SEEDED antibacterial
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A organic heterotetracyclic compound that is 10H-benzo[b]xanthene-7,10,12-trione substituted by hydroxy groups at positions 6 and 11, methoxy groups at positions 3 and 8 and a methyl group at position 1.
Structure
| Standard InChIKey | ZOQMSOSJEWBMHP-UHFFFAOYSA-N |
|---|---|
| SMILES | CC1=CC(=CC2=C1C(=O)C3=C(O2)C(=C4C(=C3O)C(=O)C=C(C4=O)OC)O)OC |
| Stereochemistry | fully defined |
| Cross-references | pubchem:5281730 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fusarium fujikuroi IMI 58289 NCBITaxon:1279085 |
SOURCE_ASSERTION | mibig:BGC0000030 | DOI:10.1016/j.jbiosc.2013.09.017 |
Occurrences 8
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Fusarium vanettenii NCBITaxon:2747968 |
LOTUS | DOI:10.1016/J.JBIOSC.2013.09.017 |
| Fusarium sp. NCBITaxon:29916 |
CHEBI | PMID:24183988 |
| Fusarium fujikuroi NCBITaxon:5127 |
LOTUS | DOI:10.1007/BF02880192 |
| Fusarium fujikuroi NCBITaxon:5127 |
LOTUS | DOI:10.1016/J.JBIOSC.2013.09.017 |
| Fusarium fujikuroi NCBITaxon:5127 |
LOTUS | DOI:10.1111/J.1365-2672.2007.03581.X |
| Fusarium oxysporum NCBITaxon:5507 |
LOTUS | DOI:10.1016/J.JBIOSC.2013.09.017 |
| Fusarium oxysporum NCBITaxon:5507 |
LOTUS | DOI:10.1021/NP060394T |
| Fusarium oxysporum NCBITaxon:5507 |
LOTUS | DOI:10.7164/ANTIBIOTICS.29.1050 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000030 | Fusarium fujikuroi IMI 58289 NCBITaxon:1279085 |
CLUSTER_UNSTATED | genbank:HF679027.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — CHEBI:3096 (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000030 | MIBIG | 3 |
| CHEBI:3096 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/bikaverin.yaml, which is generated from the committed inventories. Neither is edited by hand.