lasalocid
CHEBI:92181 EXACT SEEDED antiparasitic
A polyether antibiotic used for prevention and treatment of coccidiosis in poultry.
Structure
| Standard InChIKey | BBMULGJBVDDDNI-OWKLGTHSSA-N |
|---|---|
| SMILES | [H][C@@](C)(CCC1=C(C(O)=O)C(O)=C(C)C=C1)[C@]([H])(O)[C@]([H])(C)C(=O)[C@]([H])(CC)[C@@]1([H])O[C@@](CC)(C[C@@H]1C)[C@@]1([H])CC[C@](O)(CC)[C@H](C)O1 |
| Stereochemistry | fully defined |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. NCBITaxon:1931 |
SOURCE_ASSERTION | mibig:BGC0001648 | PMID:19129623 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1039/C29700000071 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1271/BBB.80631 |
| Streptomyces lasalocidi NCBITaxon:324833 |
CHEBI | PMID:32228806 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001648 | Streptomyces sp. NCBITaxon:1931 |
CLUSTER_UNSTATED | genbank:KT591188.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:92181 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001648 | MIBIG | 5 |
| CHEBI:92181 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/lasalocid.yaml, which is generated from the committed inventories. Neither is edited by hand.