genome streamlining

Edge evidence

• oligotrophic environment selects for genome streamlining METPO:2007401

  Resource limitation and large Ne favor minimizing cellular cost via genome reduction.

  • DOI:10.1038/ismej.2014.60 Giovannoni et al. articulate streamlining theory for abundant oligotrophic microbes.
• reductive genome evolution causes genome streamlining biolink:causes

  Reductive evolution is the population-genetic process realizing the streamlined-genome phenotype.

  • DOI:10.1038/nrmicro3331 Batut et al. compare reductive genome evolution across the bacterial population-size spectrum.
• oligotrophic environment selects for smaller microbial genome size METPO:2007401

  Resource-poor oligotrophic waters select for smaller microbial genomes across free-living marine microbes.

  • DOI:10.1038/s41467-023-36988-x Ngugi 2023: "small microbial genomes in the resource-poor photic ocean"; broad comparative support across 364 marine metagenomes.
• genome streamlining associated with depletion of metabolic genes biolink:associated_with

  Streamlined genomes show a generalizable depletion of metabolic genes.

  • DOI:10.1038/s41467-024-50368-z Dong 2024: "reduced genome sizes associated with a depletion of metabolic genes"; generalizable signature of streamlined genomes under stress.
• genome streamlining promotes metabolic cross-feeding RO:0002213

  Streamlining and resulting auxotrophies promote metabolic cross-feeding in bacterioplankton communities.

  • DOI:10.1038/s41467-024-46374-w Giordano 2024: "genome streamlining and metabolic auxotrophies as central joint mechanisms shaping bacterioplankton community assembly".
• reduced cofactor/vitamin biosynthesis increases dependence on dependence on exogenous B-vitamin precursors

  Loss of cofactor/vitamin biosynthesis increases reliance on exogenous B-vitamin precursors and products.

  • DOI:10.1038/s41467-024-46374-w Giordano 2024: "reliance ... on exogenous B1 and B12 precursors/products"; Black Queen-like public-goods dependency.
• reductive genome evolution removes genes with marginal fitness benefit

  Selection in oligotrophic lineages removes genes with marginal fitness benefit, realizing genome reduction.

  • DOI:10.1093/femsre/fuac043 Diez 2023 review: "genome reduction was driven by selection removing genes with marginal fitness benefit"; classical streamlining theory.