coated vesicle membrane

GO:0030662 · Membrane organelle · Membrane · Proposed

The lipid bilayer surrounding a coated vesicle. [GO:0030662]

Part of: coated vesicle (GO:0030135)

Has part: vesicle coat (GO:0030120)

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
coated vesicle membrane lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Lipid-bilayer constituent of the coated vesicle membrane that surrounds a coated vesicle. `GO:0030662` GO:0030662 defines the coated vesicle membrane as the lipid bilayer surrounding a coated vesicle. `GO:0030665` GO:0030665 identifies the clathrin-coated vesicle membrane child of the coated vesicle membrane. `GO:0030663` GO:0030663 identifies the COPI-coated vesicle membrane child of the coated vesicle membrane. `GO:0012507` GO:0012507 identifies the ER-to-Golgi transport vesicle membrane child carried by COPII-coated vesicles.

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast forms COPII-coated ER-to-Golgi transport vesicles from endoplasmic-reticulum membranes using Sar1p, Sec23p, Sec24p, Sec13p, and Sec31p coat machinery. [PMID:8004676]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast COPII reconstitution model in which Sec proteins drive coated vesicle formation on chemically defined liposomes. [PMID:9568718]

The coated vesicle membrane is the lipid-bilayer boundary of a coated vesicle.

Subject	Predicate	Object	Evidence
coated vesicle membrane	is part of	coated vesicle	`GO:0030662` GO:0030662 identifies the coated vesicle membrane. `GO:0030135` GO:0030135 identifies the containing coated vesicle.
vesicle coat	is part of	coated vesicle membrane	`GO:0030120` GO:0030120 records vesicle coat as part of the coated vesicle membrane. `GO:0030662` GO:0030662 identifies the coated vesicle membrane.
coated vesicle membrane	bounds	coated vesicle	`GO:0030662` GO:0030662 defines the coated vesicle membrane as the lipid bilayer surrounding a coated vesicle.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for the lipid constituent of the coated vesicle membrane. The record is exactly grounded to GO:0030662, but the coated vesicle membrane lipid-bilayer constituent is intentionally left as reviewed-label-only until an exact source-neutral lipid or membrane-constituent CURIE is curated.
INTERPRETATION (RESOLVED): Keep the vesicle coat as a whole-vesicle part rather than as a lipid-bilayer membrane component. GO:0030662 denotes the lipid bilayer surrounding a coated vesicle, whereas GO:0030120 denotes the protein coat on the whole coated vesicle.

GO:0030662 Gene Ontology cellular-component term for the coated vesicle membrane.
GO:0030659 Gene Ontology cellular-component parent term for cytoplasmic vesicle membranes.
GO:0030135 Gene Ontology cellular-component term for the containing coated vesicle.
GO:0030665 Gene Ontology cellular-component child term for clathrin-coated vesicle membranes.
GO:0030663 Gene Ontology cellular-component child term for COPI-coated vesicle membranes.
GO:0012507 Gene Ontology cellular-component child term for ER-to-Golgi transport vesicle membranes.
GO:0030120 Gene Ontology cellular-component term for the protein vesicle coat.
PMID:8004676 Barlowe et al. 1994, COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum, Cell.
PMID:9568718 Matsuoka et al. 1998, COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes, Cell.

2026-09-16T03:41:02Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-16T03:41:51Z codex · EXPANDED_RECORD — Added cytoplasmic-vesicle membrane parentage, coated-vesicle parthood, a reviewed-label-only lipid-bilayer component, Saccharomyces scope, GO/DOI evidence, a nonmechanistic membrane topology graph, and lipid grounding plus coat-boundary discussions.
2026-09-16T03:52:50Z codex · ADDRESSED_PR_REVIEW — Resolved PR #1059 review issue #1060 by mirroring GO:0030120 vesicle coat parthood as has_part and as an evidence-backed topology edge while keeping coat proteins out of the lipid-bilayer component list.
2026-09-16T03:53:19Z codex · NORMALIZED_REVIEW_FIX_YAML — Moved has_part next to part_of after the PR #1059 review fix so mereology fields emit in the same order as nearby records.
2026-09-21T09:25:14Z codex · REPLACED_UNREADABLE_EVIDENCE — Resolved #1229 by routing Barlowe et al. 1994 COPII evidence through reachable PMID:8004676 instead of the unreadable Cell DOI.
2026-09-21T11:34:06Z codex · REPLACED_UNREADABLE_EVIDENCE — Resolved #1237 by routing Matsuoka et al. 1998 COPII liposome evidence through reachable PMID:9568718 instead of the unreadable Cell DOI.