contractile vacuole lumen

cellstructuremech:contractile_vacuole_lumen · Membrane organelle · Subcellular region · Proposed

The contractile vacuole compartment bounded by the contractile vacuole membrane. [uniprot.location:SL-0320 — Contractile vacuole lumen]

Synonyms: contractile vacuolar lumen

Part of: contractile vacuole (GO:0000331)

Xrefs: uniprot.location:SL-0320 — Contractile vacuole lumen

Taxonomic distribution

NCBITaxon:2759 Eukaryota — RARE: Contractile-vacuole lumens occur in the patchy subset of unicellular freshwater and soil eukaryotes that build contractile vacuoles. [DOI:10.1016/j.ejop.2024.126078]

NCBITaxon:44030 Paramecium multimicronucleatum — Ciliate model in which microelectrodes placed in the contractile vacuole measured lumen-side membrane potential during the filling phase. [DOI:10.1242/jeb.205.20.3261]
NCBITaxon:3055 Chlamydomonas reinhardtii — Freshwater alga used to quantify contractile-vacuole volume changes and osmolarity-responsive filling and discharge cycles. [DOI:10.1128/EC.00163-14]

contractile-vacuole water accumulation — The contractile vacuole lumen expands as excess water enters the vacuole before periodic systolic discharge.
- DOI:10.1016/S0074-7696(02)15015-7 Allen and Naitoh 2002 review fluid filling and discharge as phases of the contractile-vacuole cycle.
- DOI:10.1128/EC.00163-14 Komsic-Buchmann et al. 2014 measured contractile vacuole volume and contraction interval changes in Chlamydomonas under altered osmolarity.

The contractile vacuole lumen is the water-filled compartment inside a contractile vacuole and bounded by the contractile vacuolar membrane.

Subject	Predicate	Object	Evidence
contractile vacuole lumen	is part of	contractile vacuole	`uniprot.location:SL-0320` — Contractile vacuole lumen UniProt SL-0320 places the contractile vacuole lumen under the contractile vacuole subcellular location. `GO:0000331` GO:0000331 identifies the containing contractile vacuole.
contractile vacuolar membrane	bounds	contractile vacuole lumen	`uniprot.location:SL-0320` — Contractile vacuole lumen UniProt SL-0320 defines the contractile vacuole lumen as bounded by the contractile vacuole membrane. `GO:0031164` GO:0031164 identifies the membrane surrounding the contractile vacuole.

INTERPRETATION (RESOLVED): Represent the contractile vacuolar membrane as the boundary of the lumen rather than as a lumen component. UniProt SL-0320 denotes the contractile vacuole compartment bounded by the contractile vacuole membrane, whereas GO:0031164 denotes the surrounding lipid bilayer.

uniprot.location:SL-0320 — Contractile vacuole lumen UniProt Subcellular Location entry SL-0320 identifies the contractile vacuole lumen, lists contractile vacuolar lumen as an exact synonym, and places the lumen under the contractile vacuole.
GO:0005775 Gene Ontology cellular-component term for the broader vacuolar lumen class.
GO:0000331 Gene Ontology cellular-component term for the containing contractile vacuole.
GO:0031164 Gene Ontology cellular-component term for the contractile vacuolar membrane that bounds this lumen.
DOI:10.1016/S0074-7696(02)15015-7 Allen and Naitoh 2002, Osmoregulation and contractile vacuoles of protozoa, International Review of Cytology.
DOI:10.1128/EC.00163-14 Komsic-Buchmann, Wostehoff and Becker 2014, The contractile vacuole as a key regulator of cellular water flow in Chlamydomonas reinhardtii, Eukaryotic Cell.
DOI:10.1242/jeb.205.20.3261 Gronlien et al. 2002, Relationship between the membrane potential of the contractile vacuole complex and its osmoregulatory activity in Paramecium multimicronucleatum, Journal of Experimental Biology.
DOI:10.1016/j.ejop.2024.126078 More et al. 2024, Contractile vacuoles: a rapidly expanding and occasionally diminishing understanding, European Journal of Protistology.

2026-09-13T17:47:03Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-13T17:47:56Z codex · EXPANDED_RECORD — Added the UniProt SL synonym and xref, vacuolar-lumen parentage, contractile-vacuole parthood, eukaryotic distribution with Paramecium and Chlamydomonas examples, a water-accumulation function, GO/UniProt/DOI evidence, a nonmechanistic lumen-topology graph, and a resolved boundary interpretation.