COPI-coated vesicle lumen

cellstructuremech:copi_coated_vesicle_lumen · Membrane organelle · Subcellular region · Proposed

The COPI-coated vesicle compartment bounded by the COPI-coated vesicle membrane. [uniprot.location:SL-0321 — COPI-coated vesicle lumen]

Part of: COPI-coated vesicle (GO:0030137)

Xrefs: uniprot.location:SL-0321 — COPI-coated vesicle lumen

Taxonomic distribution

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast has coatomer-dependent COPI-coated vesicles that carry early secretory cargo for retrograde retrieval. [DOI:10.1091/mbc.e02-11-0736]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast model in which coatomer mutants established COPI roles in Golgi-to-ER retrieval and early secretory trafficking. [DOI:10.1091/mbc.e02-11-0736]

The COPI-coated vesicle membrane bounds the COPI-coated vesicle lumen inside the coated vesicle.

Subject	Predicate	Object	Evidence
COPI-coated vesicle lumen	is part of	COPI-coated vesicle	`uniprot.location:SL-0321` — COPI-coated vesicle lumen UniProt SL-0321 places the COPI-coated vesicle lumen under the COPI-coated vesicle. `GO:0030137` GO:0030137 identifies the enclosing COPI-coated vesicle.
COPI-coated vesicle membrane	bounds	COPI-coated vesicle lumen	`uniprot.location:SL-0321` — COPI-coated vesicle lumen UniProt SL-0321 describes the lumen as bounded by the COPI-coated vesicle membrane. `GO:0030663` GO:0030663 identifies the surrounding COPI-coated vesicle membrane.

uniprot.location:SL-0321 — COPI-coated vesicle lumen UniProt Subcellular Location entry SL-0321 identifies the COPI-coated vesicle lumen, places it under cytoplasmic vesicle lumen, and names it part of COPI-coated vesicle.
GO:0060205 Gene Ontology cellular-component parent term for cytoplasmic vesicle lumen.
GO:0030137 Gene Ontology cellular-component term for the enclosing COPI-coated vesicle.
GO:0030663 Gene Ontology cellular-component term for the COPI-coated vesicle membrane bounding the lumen.
DOI:10.1091/mbc.e02-11-0736 Sandmann et al. 2003, Suppression of Coatomer Mutants by a New Protein Family with COPI and COPII Binding Motifs in Saccharomyces cerevisiae, Molecular Biology of the Cell.

2026-09-14T22:00:01Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-14T22:00:49Z codex · EXPANDED_RECORD — Added cytoplasmic-vesicle-lumen parentage, COPI-coated-vesicle parthood, the UniProt SL-0321 xref, Saccharomyces scope, GO/UniProt/DOI evidence, and a nonmechanistic COPI-coated-vesicle lumen topology graph.
2026-09-21T11:01:21Z codex · REPLACED_UNREADABLE_EVIDENCE — Resolved #1235 by replacing unreadable Letourneur COPI evidence with reachable Sandmann et al. 2003 Golgi-to-ER retrieval evidence.