Cvt vesicle lumen
The Cvt vesicle compartment bounded by the Cvt vesicle membrane. [uniprot.location:SL-0323 — Cvt vesicle lumen]
Part of: Cvt vesicle (GO:0033107)
Xrefs: uniprot.location:SL-0323 — Cvt vesicle lumen
Taxonomic distribution
NCBITaxon:4932Saccharomyces cerevisiae — COMMON: Budding-yeast Cvt vesicles are double-membrane carriers whose bounded lumen encloses cytoplasm-to-vacuole targeting cargo before vacuolar delivery. [DOI:10.1091/mbc.e03-07-0479]
Canonical examples
NCBITaxon:4932Saccharomyces cerevisiae — Budding-yeast model used to characterize Cvt vesicle assembly and its early-secretory-pathway requirements. [DOI:10.1091/mbc.e03-07-0479]
Mechanism graphs
Cvt vesicle lumen topology (FUNCTION)
A Cvt vesicle membrane bounds the Cvt vesicle lumen inside the completed double-membrane Cvt vesicle.
| Subject | Predicate | Object | Evidence |
|---|---|---|---|
| Cvt vesicle lumen | is part of | Cvt vesicle |
|
| Cvt vesicle membrane | bounds | Cvt vesicle lumen |
|
Evidence
uniprot.location:SL-0323— Cvt vesicle lumen UniProt Subcellular Location entry SL-0323 identifies the Cvt vesicle lumen, places it under cytoplasmic vesicle lumen, and names it part of Cvt vesicle.GO:0060205Gene Ontology cellular-component parent term for cytoplasmic vesicle lumen.GO:0033107Gene Ontology cellular-component term for the enclosing Cvt vesicle.GO:0033110Gene Ontology cellular-component term for either Cvt vesicle membrane bilayer bounding the lumen.DOI:10.1091/mbc.e03-07-0479Reggiori et al. 2004, Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae, Molecular Biology of the Cell.
Curation history
2026-09-14T21:40:08Zcodex · CREATED_RECORD — Scaffolded by scripts/new_record.py2026-09-14T21:40:35Zcodex · EXPANDED_RECORD — Added cytoplasmic-vesicle-lumen parentage, Cvt-vesicle parthood, the UniProt SL-0323 xref, Saccharomyces scope, GO/UniProt/DOI evidence, and a nonmechanistic Cvt-vesicle-lumen topology graph.
Source: data/structures/membrane_organelle/cvt_vesicle_lumen.yaml