endocytic vesicle membrane

GO:0030666 · Membrane organelle · Membrane · Proposed

The lipid bilayer surrounding an endocytic vesicle. [GO:0030666]

Part of: endocytic vesicle (GO:0030139)

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
endocytic vesicle membrane lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Lipid-bilayer constituent of the endocytic vesicle membrane that surrounds an endocytic vesicle. `GO:0030666` GO:0030666 identifies the membrane surrounding an endocytic vesicle.

NCBITaxon:4932 Saccharomyces cerevisiae — COMMON: Budding yeast recruits clathrin and adaptor proteins to cortical actin-based endocytic sites. [DOI:10.1016/j.devcel.2005.04.014]

NCBITaxon:4932 Saccharomyces cerevisiae — Budding-yeast model in which cortical endocytic modules defined the timing of endocytic vesicle membrane coat assembly and internalization. [DOI:10.1016/j.cell.2005.09.024]

The endocytic vesicle membrane is the lipid-bilayer boundary that surrounds an endocytic vesicle and encloses its lumen.

Subject	Predicate	Object	Evidence
endocytic vesicle membrane	is part of	endocytic vesicle	`GO:0030666` GO:0030666 records the endocytic vesicle membrane as part of GO:0030139. `GO:0030139` GO:0030139 identifies the containing endocytic vesicle.
endocytic vesicle membrane	bounds	endocytic vesicle	`GO:0030666` GO:0030666 records a bounding-layer relationship to GO:0030139. `GO:0098588` GO:0098588 identifies organelle bounding membranes.
endocytic vesicle membrane	bounds	endocytic vesicle lumen	`GO:0030666` GO:0030666 identifies the membrane surrounding an endocytic vesicle. `GO:0071682` GO:0071682 defines the lumen by enclosure within the endocytic vesicle membrane.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for endocytic vesicle membrane lipids. GO:0030666 exactly grounds the endocytic vesicle membrane, but the generic lipid-bilayer constituent is intentionally left reviewed-label-only until an exact lipid or membrane-constituent CURIE is curated.
INTERPRETATION (RESOLVED): Keep the clathrin coat off the generic endocytic vesicle membrane record. GO:0030666 spans the membrane around endocytic vesicles, while GO:0030128 is a coat part of the narrower GO:0030669 clathrin-coated endocytic vesicle membrane child.

GO:0030666 Gene Ontology cellular-component term for the endocytic vesicle membrane.
GO:0030659 Gene Ontology cellular-component parent term for cytoplasmic vesicle membranes.
GO:0098588 Gene Ontology cellular-component parent term for organelle bounding membranes.
GO:0030139 Gene Ontology cellular-component term for the whole endocytic vesicle.
GO:0071682 Gene Ontology cellular-component term for the endocytic vesicle lumen.
GO:0030669 Gene Ontology cellular-component child term for clathrin-coated endocytic vesicle membranes.
GO:0030128 Gene Ontology cellular-component term for the clathrin coat of an endocytic vesicle.
DOI:10.1016/j.devcel.2005.04.014 Newpher et al. 2005, In Vivo Dynamics of Clathrin and Its Adaptor-Dependent Recruitment to the Actin-Based Endocytic Machinery in Yeast, Developmental Cell.
DOI:10.1016/j.cell.2005.09.024 Kaksonen, Toret and Drubin 2005, A Modular Design for the Clathrin- and Actin-Mediated Endocytosis Machinery, Cell.

2026-09-16T10:25:31Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-16T10:25:50Z codex · EXPANDED_RECORD — Added cytoplasmic-vesicle-membrane and bounding-membrane parentage, whole endocytic vesicle parthood, a reviewed-label-only lipid-bilayer component, Saccharomyces endocytic-site scope, GO/DOI evidence, a nonmechanistic endocytic-vesicle membrane topology graph, and lipid-grounding plus clathrin-coat boundary discussions.
2026-09-16T10:37:30Z codex · ADDRESSED_PR_REVIEW — Resolved issue #1087 by narrowing the Saccharomyces cerevisiae taxonomic-distribution note to adaptor and clathrin recruitment at cortical endocytic sites.