glyoxysomal membrane

GO:0046861 · Membrane organelle · Membrane · Proposed

The membrane surrounding the glyoxysome. [GO:0046861]

Synonyms: glyoxysome membrane

Part of: glyoxysome (GO:0009514)

Xrefs: uniprot.location:SL-0130 — Glyoxysome membrane

Components

Component	Type	Part of / acts on	Grounding	Genes	Stoichiometry	Essential	Role
glyoxysomal lipid bilayer	Lipid	part of	Reviewed label only (reviewed name; no accession asserted)			ESSENTIAL	Peroxisome-related lipid bilayer that surrounds the glyoxysome and separates the glyoxysomal matrix from the cytosol. `GO:0046861` GO:0046861 identifies the glyoxysomal membrane as the membrane surrounding a glyoxysome. `DOI:10.1007/BF00309930` de Zoysa and Connerton 1994 studied matrix-protein targeting into Neurospora crassa glyoxysomes.

NCBITaxon:5141 Neurospora crassa — COMMON: Neurospora crassa forms acetate-induced glyoxysomes whose membranes bound glyoxylate-cycle matrix compartments. [DOI:10.1007/BF00309930]

NCBITaxon:5141 Neurospora crassa — Filamentous-fungal model used to test import of matrix proteins across the glyoxysomal membrane under acetate-induced growth conditions. [DOI:10.1007/BF00309930]

glyoxysomal matrix boundary — The glyoxysomal membrane forms the boundary around the glyoxysomal matrix compartment that contains glyoxylate-cycle enzymes.
- GO:0046861 GO:0046861 identifies the glyoxysomal membrane as the membrane surrounding a glyoxysome.
- GO:0031908 GO:0031908 defines the glyoxysomal lumen as the matrix volume enclosed by the glyoxysome membrane.
- GO:0009514 GO:0009514 defines glyoxysomes as peroxisome specializations that contain glyoxylate-pathway enzymes.

The glyoxysomal membrane surrounds the organelle and encloses the glyoxylate-cycle matrix compartment.

Subject	Predicate	Object	Evidence
glyoxysomal membrane	is part of	glyoxysome	`GO:0046861` GO:0046861 identifies the glyoxysomal membrane as surrounding a glyoxysome. `uniprot.location:SL-0130` — Glyoxysome membrane UniProt SL-0130 places the glyoxysome membrane under the glyoxysome subcellular location.
glyoxysomal lumen	is enclosed by	glyoxysomal membrane	`GO:0031908` GO:0031908 defines the glyoxysomal lumen as the volume enclosed by the glyoxysome membrane. `GO:0046861` GO:0046861 identifies the membrane surrounding a glyoxysome. `uniprot.location:SL-0333` — Glyoxysome matrix UniProt SL-0333 maps the glyoxysome matrix to the glyoxysomal lumen.

CURATION_TODO (OPEN): Resolve an exact source-neutral grounding for the generic lipid constituent of the glyoxysomal membrane. The record is exactly grounded to GO:0046861, but no glyoxysome-specific lipid or lipid-bilayer CURIE was curated for the membrane constituent.

GO:0046861 Gene Ontology cellular-component term for glyoxysomal membrane.
GO:0005778 Gene Ontology cellular-component parent term for peroxisomal membrane.
GO:0009514 Gene Ontology cellular-component term for the containing glyoxysome.
GO:0031908 Gene Ontology cellular-component term for the glyoxysomal lumen bounded by the glyoxysomal membrane.
uniprot.location:SL-0130 — Glyoxysome membrane UniProt Subcellular Location entry SL-0130 maps Glyoxysome membrane to GO:0046861 and lists glyoxysomal membrane as an exact synonym.
uniprot.location:SL-0333 — Glyoxysome matrix UniProt Subcellular Location entry SL-0333 maps Glyoxysome matrix to GO:0031908 under the containing glyoxysome.
DOI:10.1007/BF00309930 de Zoysa and Connerton 1994, The function and specificity of the C-terminal tripeptide glyoxysomal targeting signal in Neurospora crassa, Current Genetics.

2026-09-13T17:01:22Z codex · CREATED_RECORD — Scaffolded by scripts/new_record.py
2026-09-13T17:01:46Z codex · EXPANDED_RECORD — Added the UniProt SL glyoxysome-membrane synonym and xref, peroxisomal-membrane parentage, glyoxysome parthood, a label-only lipid-bilayer component, Neurospora scope, a matrix-boundary function, GO/UniProt/DOI evidence, a nonmechanistic glyoxysomal-membrane topology graph, and a lipid-grounding TODO.